Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus MA Ansari, V Pedergnana, C LC Ip, A Magri, A Von Delft, D Bonsall, ... Nature genetics 49 (5), 666-673, 2017 | 126 | 2017 |
Resistance analysis of genotype 3 hepatitis C virus indicates subtypes inherently resistant to nonstructural protein 5A inhibitors D Smith, A Magri, D Bonsall, CLC Ip, A Trebes, A Brown, P Piazza, ... Hepatology 69 (5), 1861-1872, 2019 | 78 | 2019 |
Efficacy of NS5A inhibitors against unusual and potentially difficult-to-treat HCV subtypes commonly found in sub-Saharan Africa and South East Asia D Nguyen, D Smith, A Vaughan-Jackson, A Magri, E Barnes, P Simmonds, ... Journal of Hepatology 73 (4), 794-799, 2020 | 36 | 2020 |
An immune dysfunction score for stratification of patients with acute infection based on whole-blood gene expression E Cano-Gamez, KL Burnham, C Goh, A Allcock, ZH Malick, L Overend, ... Science translational medicine 14 (669), eabq4433, 2022 | 31 | 2022 |
Amino acid substitutions in genotype 3a hepatitis C virus polymerase protein affect responses to sofosbuvir PAC Wing, M Jones, M Cheung, S DaSilva, C Bamford, WYJ Lee, ... Gastroenterology 157 (3), 692-704. e9, 2019 | 30 | 2019 |
Interpreting viral deep sequencing data with GLUE JB Singer, EC Thomson, J Hughes, E Aranday-Cortes, J McLauchlan, ... Viruses 11 (4), 323, 2019 | 28 | 2019 |
Real world SOF/VEL/VOX retreatment outcomes and viral resistance analysis for HCV patients with prior failure to DAA therapy DA Smith, D Bradshaw, JL Mbisa, CF Manso, DF Bibby, JB Singer, ... Journal of Viral Hepatitis 28 (9), 1256-1264, 2021 | 24 | 2021 |
Electronic health informatics data to describe clearance dynamics of hepatitis B surface antigen (HBsAg) and e antigen (HBeAg) in chronic hepatitis B virus infection LO Downs, DA Smith, SF Lumley, M Patel, AL McNaughton, J Mokaya, ... MBio 10 (3), 10.1128/mbio. 00699-19, 2019 | 23 | 2019 |
Treatment advantage in HBV/HIV coinfection compared to HBV monoinfection in a South African cohort TG Maponga, AL McNaughton, M Van Schalkwyk, S Hugo, C Nwankwo, ... Journal of Infection 81 (1), 121-130, 2020 | 22 | 2020 |
Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure DA Smith, C Fernandez-Antunez, A Magri, R Bowden, N Chaturvedi, ... Nature communications 12 (1), 6105, 2021 | 13 | 2021 |
Hepatitis B virus (HBV) viral load, liver and renal function in adults treated with tenofovir disoproxil fumarate (TDF) vs. untreated: a retrospective longitudinal UK cohort study T Wang, DA Smith, C Campbell, J Mokaya, O Freeman, H Salih, ... BMC infectious diseases 21 (1), 610, 2021 | 12 | 2021 |
National Institute for Health Research Health Informatics Collaborative: development of a pipeline to collate electronic clinical data for viral hepatitis research DA Smith, T Wang, O Freeman, C Crichton, H Salih, PC Matthews, ... BMJ health & care informatics 27 (3), 2020 | 12* | 2020 |
Bimodal distribution and set point HBV DNA viral loads in chronic infection: retrospective analysis of cohorts from the UK and South Africa LO Downs, S Vawda, PA Bester, KA Lythgoe, T Wang, AL McNaughton, ... Wellcome Open Research 5, 2020 | 12 | 2020 |
Longitudinal analysis of the utility of liver biochemistry as prognostic markers in hospitalized patients with corona virus disease 2019 T Wang, DA Smith, C Campbell, S Harris, H Salih, KA Várnai, K Woods, ... Hepatology Communications 5 (9), 1586-1604, 2021 | 10 | 2021 |
Cohort Profile: The National Institute for Health Research Health Informatics Collaborative: Hepatitis B Virus (NIHR HIC HBV) research dataset T Wang, DA Smith, C Campbell, O Freeman, Z Moysova, T Noble, ... International Journal of Epidemiology 52 (1), e27-e37, 2023 | 9 | 2023 |
Strategic treatment optimization for HCV (STOPHCV1): a randomised controlled trial of ultrashort duration therapy for chronic hepatitis C GS Cooke, S Pett, L McCabe, C Jones, R Gilson, S Verma, SD Ryder, ... Wellcome Open Research 6, 2021 | 9 | 2021 |
High cure rates for hepatitis c virus genotype 6 in advanced liver fibrosis with 12 weeks sofosbuvir and daclatasvir: the vietnam SEARCH study B Flower, L McCabe, C Le Ngoc, H Le Manh, P Le Thanh, T Dang Trong, ... Open forum infectious diseases 8 (7), ofab267, 2021 | 8 | 2021 |
Characterization of hepatitis C virus resistance to grazoprevir reveals complex patterns of mutations following on-treatment breakthrough that are not observed at relapse D Bonsall, S Black, AYM Howe, R Chase, P Ingravallo, I Pak, A Brown, ... Infection and Drug Resistance, 1119-1135, 2018 | 7 | 2018 |
High number of SARS-CoV-2 persistent infections uncovered through genetic analysis of samples from a large community-based surveillance study M Ghafari, M Hall, T Golubchik, D Ayoubkhani, T House, ... medRxiv, 2023.01. 29.23285160, 2023 | 4 | 2023 |
Impact of the COVID-19 pandemic on routine surveillance for adults with chronic hepatitis B virus (HBV) infection in the UK C Campbell, T Wang, DA Smith, O Freeman, T Noble, KA Várnai, S Harris, ... Wellcome Open Research 7, 2022 | 4 | 2022 |