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Matthew L Fidler
Matthew L Fidler
Verified email at novartis.com
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Nonlinear mixed‐effects model development and simulation using nlmixr and related R open‐source packages
M Fidler, JJ Wilkins, R Hooijmaijers, TM Post, R Schoemaker, MN Trame, ...
CPT: pharmacometrics & systems pharmacology 8 (9), 621-633, 2019
522019
Pharmacodynamic attainment of the synergism of meropenem and fosfomycin combination against Pseudomonas aeruginosa producing metallo-β-lactamase
J Albiero, J Mazucheli, JPR Barros, MMA Szczerepa, SAB Nishiyama, ...
Antimicrobial Agents and Chemotherapy 63 (6), 10.1128/aac. 00126-19, 2019
342019
Flexible interaction model for complex interactions of multiple anesthetics
M Fidler, SE Kern
The Journal of the American Society of Anesthesiologists 105 (2), 286-296, 2006
342006
Ranibizumab population pharmacokinetics and free VEGF pharmacodynamics in preterm infants with retinopathy of prematurity in the RAINBOW trial
M Fidler, BW Fleck, A Stahl, N Marlow, JE Chastain, J Li, D Lepore, ...
Translational Vision Science & Technology 9 (8), 43-43, 2020
332020
Effect of initial subcellular localization of progesterone receptor on import kinetics and transcriptional activity
H Li, ML Fidler, CS Lim
Molecular pharmaceutics 2 (6), 509-518, 2005
292005
RxODE: facilities for simulating from ODE-based models
M Fidler, M Hallow, J Wilkins, W Wang
R package version 1 (9), 2019
192019
nlmixr: Nonlinear mixed effects models in population pharmacokinetics and pharmacodynamics
M Fidler, Y Xiong, R Schoemaker, J Wilkins, M Trame, T Post, W Wang
R package version 2 (1), 2021
112021
Performance of the SAEM and FOCEI algorithms in the open‐source, nonlinear mixed effect modeling tool nlmixr
R Schoemaker, M Fidler, C Laveille, JJ Wilkins, R Hooijmaijers, TM Post, ...
CPT: Pharmacometrics & Systems Pharmacology 8 (12), 923-930, 2019
92019
R and nlmixr as a gateway between statistics and pharmacometrics
M Fidler, R Hooijmaijers, R Schoemaker, JJ Wilkins, Y Xiong, W Wang
CPT: Pharmacometrics & Systems Pharmacology 10 (4), 283, 2021
62021
nlmixr: Nonlinear Mixed Effects Models in Population Pharmacokinetics and Pharmacodynamics, 2018, r package version 1.0. 0-7
M Fidler, Y Xiong, R Schoemaker, J Wilkins, M Trame, T Post, W Wang
6
Projected 24-hour post-dose ocular itching scores post-treatment with olopatadine 0.7% versus 0.2%
ML Fidler, A Ogundele, D Covert, R Sarangapani
Journal of Pharmacokinetics and Pharmacodynamics 45, 593-605, 2018
42018
Modelling the interaction of propofol and remifentanil by means of an adaptive neuro fuzzy inference system (ANFIS): A-514
P Gambús, E Jensen, GM Palli, M Fidler, S Kern
European Journal of Anaesthesiology| EJA 23, 134, 2006
32006
Package ‘RxODE’
M Hallow, ML Fidler, W Wang
12017
Package ‘lbfgsb3c’
ML Fidler, JC Nash, C Zhu, R Byrd, J Nocedal, JL Morales
2024
Package ‘rxode2’
MML Fidler, M Hallow, W Wang, MW Wang
2024
Pharmacodynamic Model to Predict Ocular Itching Outcomes at 24 Hours Post-Treatment with Olopatadine (0.77% or 0.2%)
ML Fidler, M Stat, A Narvekar, D Covert, R Sarangapani
Journal of Allergy and Clinical Immunology 137 (2), AB257, 2016
2016
A Model-Based Approach to Describe Olopatadine Itching in Ocular Allergy Patients for a CAC Study
M Fidler, A Narvekar, R Sarangapani
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 41, S63-S64, 2014
2014
A Model-based Approach to Support Once-a-day Formulation Development for Topically Administered Brinzolamide in Glaucoma Patients
M Fidler, A Weber, R Sarangapani
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 40, S69-S70, 2013
2013
Modeling interactions of low dose propfol and remifentanil: A-511
ML Fidler, PL Gambus, X Barba, EW Jensen, S Kern
European Journal of Anaesthesiology| EJA 23, 133, 2006
2006
Statistically testable parameter drug interaction modeling
ML Fidler
The University of Utah, 2006
2006
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