GPR109A is a G-protein–coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon M Thangaraju, GA Cresci, K Liu, S Ananth, JP Gnanaprakasam, ... Cancer research 69 (7), 2826-2832, 2009 | 727 | 2009 |
DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis R Pathania, S Ramachandran, S Elangovan, R Padia, P Yang, S Cinghu, ... Nature communications 6 (1), 6910, 2015 | 251 | 2015 |
SLC6A14 (ATB0,+) protein, a highly concentrative and broad specific amino acid transporter, is a novel and effective drug target for treatment of estrogen receptor-positive … S Karunakaran, S Ramachandran, V Coothankandaswamy, S Elangovan, ... Journal of Biological Chemistry 286 (36), 31830-31838, 2011 | 218 | 2011 |
SIRT1 is essential for oncogenic signaling by estrogen/estrogen receptor α in breast cancer S Elangovan, S Ramachandran, N Venkatesan, S Ananth, ... Cancer research 71 (21), 6654-6664, 2011 | 175 | 2011 |
Cloning and functional characterization of human SMCT2 (SLC5A12) and expression pattern of the transporter in kidney E Gopal, NS Umapathy, PM Martin, S Ananth, JP Gnana-Prakasam, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1768 (11), 2690-2697, 2007 | 114 | 2007 |
Hepcidin expression in mouse retina and its regulation via lipopolysaccharide/Toll-like receptor-4 pathway independent of Hfe JP Gnana-Prakasam, PM Martin, BA Mysona, P Roon, SB Smith, ... Biochemical Journal 411 (1), 79-88, 2008 | 106 | 2008 |
Deletion of the amino acid transporter Slc6a14 suppresses tumour growth in spontaneous mouse models of breast cancer E Babu, YD Bhutia, S Ramachandran, JP Gnanaprakasam, PD Prasad, ... Biochemical Journal 469 (1), 17-23, 2015 | 85 | 2015 |
Cloning and functional characterization of the proton-coupled electrogenic folate transporter and analysis of its expression in retinal cell types NS Umapathy, JP Gnana-Prakasam, PM Martin, B Mysona, Y Dun, ... Investigative ophthalmology & visual science 48 (11), 5299-5305, 2007 | 82 | 2007 |
Expression, subcellular localization, and regulation of sigma receptor in retinal muller cells G Jiang, B Mysona, Y Dun, JP Gnana-Prakasam, N Pabla, W Li, Z Dong, ... Investigative ophthalmology & visual science 47 (12), 5576-5582, 2006 | 79 | 2006 |
Expression and function of iron‐regulatory proteins in retina JP Gnana‐Prakasam, PM Martin, SB Smith, V Ganapathy IUBMB life 62 (5), 363-370, 2010 | 64 | 2010 |
Iron overload accelerates the progression of diabetic retinopathy in association with increased retinal renin expression K Chaudhary, W Promsote, S Ananth, R Veeranan-Karmegam, A Tawfik, ... Scientific reports 8 (1), 3025, 2018 | 61 | 2018 |
Absence of iron-regulatory protein Hfe results in hyperproliferation of retinal pigment epithelium: role of cystine/glutamate exchanger JP Gnana-Prakasam, M Thangaraju, K Liu, Y Ha, PM Martin, SB Smith, ... Biochemical Journal 424 (2), 243-252, 2009 | 57 | 2009 |
Expression and iron-dependent regulation of succinate receptor GPR91 in retinal pigment epithelium JP Gnana-Prakasam, S Ananth, PD Prasad, M Zhang, SS Atherton, ... Investigative ophthalmology & visual science 52 (6), 3751-3758, 2011 | 52 | 2011 |
Regulation of the cholesterol efflux transporters ABCA1 and ABCG1 in retina in hemochromatosis and by the endogenous siderophore 2, 5-dihydroxybenzoic acid S Ananth, JP Gnana-Prakasam, YD Bhutia, R Veeranan-Karmegam, ... Biochimica Et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (4), 603-612, 2014 | 50 | 2014 |
Expression and polarized localization of the hemochromatosis gene product HFE in retinal pigment epithelium PM Martin, JP Gnana-Prakasam, P Roon, RG Smith, SB Smith, ... Investigative ophthalmology & visual science 47 (10), 4238-4244, 2006 | 45 | 2006 |
Amino acid metabolism inhibits antibody-driven kidney injury by inducing autophagy K Chaudhary, R Shinde, H Liu, JP Gnana-Prakasam, ... The Journal of Immunology 194 (12), 5713-5724, 2015 | 44 | 2015 |
Iron-mediated retinal degeneration in haemojuvelin-knockout mice JP Gnana-Prakasam, A Tawfik, M Romej, S Ananth, PM Martin, SB Smith, ... Biochemical Journal 441 (2), 599-608, 2012 | 40 | 2012 |
Renal iron accelerates the progression of diabetic nephropathy in the HFE gene knockout mouse model of iron overload K Chaudhary, A Chilakala, S Ananth, A Mandala, R Veeranan-Karmegam, ... American Journal of Physiology-Renal Physiology 317 (2), F512-F517, 2019 | 35 | 2019 |
Chronic exposure to excess iron promotes EMT and cancer via p53 loss in pancreatic cancer YD Bhutia, J Ogura, PJ Grippo, C Torres, T Sato, M Wachtel, ... Asian journal of pharmaceutical sciences 15 (2), 237-251, 2020 | 31 | 2020 |
Polarized distribution of heme transporters in retinal pigment epithelium and their regulation in the iron-overload disease hemochromatosis JP Gnana-Prakasam, SK Reddy, R Veeranan-Karmegam, SB Smith, ... Investigative Ophthalmology & Visual Science 52 (12), 9279-9286, 2011 | 31 | 2011 |