Large cardiac muscle patches engineered from human induced-pluripotent stem cell–derived cardiac cells improve recovery from myocardial infarction in swine L Gao, ZR Gregorich, W Zhu, S Mattapally, Y Oduk, X Lou, R Kannappan, ... Circulation 137 (16), 1712-1730, 2018 | 393 | 2018 |
Top‐down proteomics in health and disease: Challenges and opportunities ZR Gregorich, Y Ge Proteomics 14 (10), 1195-1210, 2014 | 237 | 2014 |
MASH suite pro: a comprehensive software tool for top-down proteomics W Cai, H Guner, ZR Gregorich, AJ Chen, S Ayaz-Guner, Y Peng, ... Molecular & Cellular Proteomics 15 (2), 703-714, 2016 | 139 | 2016 |
Top-down proteomics reveals concerted reductions in myofilament and Z-disc protein phosphorylation after acute myocardial infarction Y Peng, ZR Gregorich, SG Valeja, H Zhang, W Cai, YC Chen, H Guner, ... Molecular & Cellular Proteomics 13 (10), 2752-2764, 2014 | 116 | 2014 |
Top-down proteomics: technology advancements and applications to heart diseases W Cai, TM Tucholski, ZR Gregorich, Y Ge Expert review of proteomics 13 (8), 717-730, 2016 | 107 | 2016 |
Proteomics in heart failure: top-down or bottom-up? ZR Gregorich, YH Chang, Y Ge Pflügers Archiv-European Journal of Physiology 466, 1199-1209, 2014 | 104 | 2014 |
MASH Suite: a user-friendly and versatile software interface for high-resolution mass spectrometry data interpretation and visualization H Guner, PL Close, W Cai, H Zhang, Y Peng, ZR Gregorich, Y Ge Journal of The American Society for Mass Spectrometry 25 (3), 464-470, 2014 | 94 | 2014 |
Three dimensional liquid chromatography coupling ion exchange chromatography/hydrophobic interaction chromatography/reverse phase chromatography for effective protein … SG Valeja, L Xiu, ZR Gregorich, H Guner, S Jin, Y Ge Analytical chemistry 87 (10), 5363-5371, 2015 | 86 | 2015 |
New mass-spectrometry-compatible degradable surfactant for tissue proteomics YH Chang, ZR Gregorich, AJ Chen, L Hwang, H Guner, D Yu, J Zhang, ... Journal of proteome research 14 (3), 1587-1599, 2015 | 86 | 2015 |
Distinct hypertrophic cardiomyopathy genotypes result in convergent sarcomeric proteoform profiles revealed by top-down proteomics T Tucholski, W Cai, ZR Gregorich, EF Bayne, SD Mitchell, SJ McIlwain, ... Proceedings of the National Academy of Sciences 117 (40), 24691-24700, 2020 | 76 | 2020 |
Specific enrichment of phosphoproteins using functionalized multivalent nanoparticles L Hwang, S Ayaz-Guner, ZR Gregorich, W Cai, SG Valeja, S Jin, Y Ge Journal of the American Chemical Society 137 (7), 2432-2435, 2015 | 70 | 2015 |
An unbiased proteomics method to assess the maturation of human pluripotent stem cell–derived cardiomyocytes W Cai, J Zhang, WJ de Lange, ZR Gregorich, H Karp, ET Farrell, ... Circulation research 125 (11), 936-953, 2019 | 68 | 2019 |
In-depth proteomic analysis of human tropomyosin by top-down mass spectrometry Y Peng, D Yu, Z Gregorich, X Chen, AM Beyer, DD Gutterman, Y Ge Journal of muscle research and cell motility 34, 199-210, 2013 | 54 | 2013 |
Top-down targeted proteomics reveals decrease in myosin regulatory light-chain phosphorylation that contributes to sarcopenic muscle dysfunction ZR Gregorich, Y Peng, W Cai, Y Jin, L Wei, AJ Chen, SH McKiernan, ... Journal of proteome research 15 (8), 2706-2716, 2016 | 53 | 2016 |
Novel sarcopenia-related alterations in sarcomeric protein post-translational modifications (PTMs) in skeletal muscles identified by top-down proteomics L Wei, ZR Gregorich, Z Lin, W Cai, Y Jin, SH McKiernan, S McIlwain, ... Molecular & Cellular Proteomics 17 (1), 134-145, 2018 | 37 | 2018 |
Distinct sequences and post-translational modifications in cardiac atrial and ventricular myosin light chains revealed by top-down mass spectrometry ZR Gregorich, W Cai, Z Lin, AJ Chen, Y Peng, T Kohmoto, Y Ge Journal of molecular and cellular cardiology 107, 13-21, 2017 | 36 | 2017 |
Comprehensive assessment of chamber-specific and transmural heterogeneity in myofilament protein phosphorylation by top-down mass spectrometry ZR Gregorich, Y Peng, NM Lane, JJ Wolff, S Wang, W Guo, H Guner, ... Journal of molecular and cellular cardiology 87, 102-112, 2015 | 31 | 2015 |
Impact of phosphorylation on the mass spectrometry quantification of intact phosphoproteins Z Wu, TN Tiambeng, W Cai, B Chen, Z Lin, ZR Gregorich, Y Ge Analytical chemistry 90 (8), 4935-4939, 2018 | 26 | 2018 |
Quantitative proteomics and immunohistochemistry reveal insights into cellular and molecular processes in the infarct border zone one month after myocardial infarction L Yang, ZR Gregorich, W Cai, P Zhang, B Young, Y Gu, J Zhang, Y Ge Journal of proteome research 16 (5), 2101-2112, 2017 | 26 | 2017 |
High sensitivity top–down proteomics captures single muscle cell heterogeneity in large proteoforms JA Melby, KA Brown, ZR Gregorich, DS Roberts, EA Chapman, LE Ehlers, ... Proceedings of the National Academy of Sciences 120 (19), e2222081120, 2023 | 23 | 2023 |