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Allan Haldane
Allan Haldane
Verified email at temple.edu
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Year
Array programming with NumPy
CR Harris, KJ Millman, SJ Van Der Walt, R Gommers, P Virtanen, ...
Nature 585 (7825), 357-362, 2020
156852020
del R’ıo
CR Harris, KJ Millman, SJ Van Der Walt, R Gommers, P Virtanen, ...
JF, Wiebe, M., Peterson, P., G’erard-Marchant, P., Sheppard, K., Reddy, T …, 2020
972020
Potts Hamiltonian models of protein co-variation, free energy landscapes, and evolutionary fitness
RM Levy, A Haldane, WF Flynn
Current opinion in structural biology 43, 55-62, 2017
822017
Structural propensities of kinase family proteins from a Potts model of residue co‐variation
A Haldane, WF Flynn, P He, RSK Vijayan, RM Levy
Protein Science 25 (8), 1378-1384, 2016
592016
Inference of epistatic effects leading to entrenchment and drug resistance in HIV-1 protease
WF Flynn, A Haldane, BE Torbett, RM Levy
Molecular biology and evolution 34 (6), 1291-1306, 2017
562017
Biophysical fitness landscapes for transcription factor binding sites
A Haldane, M Manhart, AV Morozov
PLoS computational biology 10 (7), e1003683, 2014
362014
The generative capacity of probabilistic protein sequence models
F McGee, S Hauri, Q Novinger, S Vucetic, RM Levy, V Carnevale, ...
Nature communications 12 (1), 6302, 2021
332021
Epistasis and entrenchment of drug resistance in HIV-1 subtype B
A Biswas, A Haldane, E Arnold, RM Levy
Elife 8, e50524, 2019
302019
Influence of multiple-sequence-alignment depth on Potts statistical models of protein covariation
A Haldane, RM Levy
Physical Review E 99 (3), 032405, 2019
252019
Coevolutionary landscape of kinase family proteins: sequence probabilities and functional motifs
A Haldane, WF Flynn, P He, RM Levy
Biophysical journal 114 (1), 21-31, 2018
202018
Mi3-GPU: MCMC-based inverse ising inference on GPUs for protein covariation analysis
A Haldane, RM Levy
Computer Physics Communications 260, 107312, 2021
182021
Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants
M Li, D Oliveira Passos, Z Shan, SJ Smith, Q Sun, A Biswas, I Choudhuri, ...
Science Advances 9 (29), eadg5953, 2023
152023
A universal scaling law determines time reversibility and steady state of substitutions under selection
M Manhart, A Haldane, AV Morozov
Theoretical population biology 82 (1), 66-76, 2012
142012
Evolutionary divergence in the conformational landscapes of tyrosine vs serine/threonine kinases
J Gizzio, A Thakur, A Haldane, RM Levy
Elife 11, e83368, 2022
82022
Limits to detecting epistasis in the fitness landscape of HIV
A Biswas, A Haldane, RM Levy
Plos one 17 (1), e0262314, 2022
72022
Unique features of different classes of G‐protein‐coupled receptors revealed from sequence coevolutionary and structural analysis
HN Do, A Haldane, RM Levy, Y Miao
Proteins: Structure, Function, and Bioinformatics 90 (2), 601-614, 2022
52022
Contingency and entrenchment of drug-resistance mutations in HIV viral proteins
I Choudhuri, A Biswas, A Haldane, RM Levy
The Journal of Physical Chemistry B 126 (50), 10622-10636, 2022
42022
The role of epistasis in determining the fitness landscape of HIV proteins
A Biswas, A Haldane, RM Levy
bioRxiv, 2021.06. 16.448646, 2021
22021
Kinetic coevolutionary models predict the temporal emergence of HIV-1 resistance mutations under drug selection pressure
A Biswas, I Choudhuri, E Arnold, D Lyumkis, A Haldane, RM Levy
Proceedings of the National Academy of Sciences 121 (15), e2316662121, 2024
2024
Evolutionary sequence and structural basis for the distinct conformational landscapes of Tyr and Ser/Thr kinases
J Gizzio, A Thakur, A Haldane, R Levy
bioRxiv, 2024.03. 08.584161, 2024
2024
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