| Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes H Shimano, N Yahagi, M Amemiya-Kudo, AH Hasty, J Osuga, Y Tamura, ... Journal of Biological Chemistry 274 (50), 35832-35839, 1999 | 838 | 1999 |
| Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter T Yoshikawa, H Shimano, M Amemiya-Kudo, N Yahagi, AH Hasty, ... Molecular and cellular biology, 2001 | 629 | 2001 |
| Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance T Matsuzaka, H Shimano, N Yahagi, T Kato, A Atsumi, T Yamamoto, ... Nature medicine 13 (10), 1193-1202, 2007 | 585 | 2007 |
| Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lepob/Lepob mice N Yahagi, H Shimano, AH Hasty, T Matsuzaka, T Ide, T Yoshikawa, ... Journal of Biological Chemistry 277 (22), 19353-19357, 2002 | 468 | 2002 |
| Transcriptional activities of nuclear SREBP-1a,-1c, and-2 to different target promoters of lipogenic and cholesterogenic genes M Amemiya-Kudo, H Shimano, AH Hasty, N Yahagi, T Yoshikawa, ... Journal of lipid research 43 (8), 1220-1235, 2002 | 450 | 2002 |
| A crucial role of sterol regulatory element-binding protein-1 in the regulation of lipogenic gene expression by polyunsaturated fatty acids N Yahagi, H Shimano, AH Hasty, M Amemiya-Kudo, H Okazaki, Y Tamura, ... Journal of Biological Chemistry 274 (50), 35840-35844, 1999 | 448 | 1999 |
| Macrophage infiltration into adipose tissue: initiation, propagation and remodeling B Surmi, A Hasty Future lipidology 3 (5), 545-556, 2008 | 378 | 2008 |
| Direct effect of cholesterol on insulin secretion: a novel mechanism for pancreatic β-cell dysfunction M Hao, WS Head, SC Gunawardana, AH Hasty, DW Piston Diabetes 56 (9), 2328-2338, 2007 | 365 | 2007 |
| Increased atherosclerosis in mice reconstituted with apolipoprotein E null macrophages S Fazio, VR Babaev, AB Murray, AH Hasty, KJ Carter, LA Gleaves, ... Proceedings of the National Academy of Sciences 94 (9), 4647-4652, 1997 | 362 | 1997 |
| Dual regulation of mouse Δ5-and Δ6-desaturase gene expression by SREBP-1 and PPARα T Matsuzaka, H Shimano, N Yahagi, M Amemiya-Kudo, T Yoshikawa, ... Journal of lipid research 43 (1), 107-114, 2002 | 355 | 2002 |
| Mouse models of the metabolic syndrome AJ Kennedy, KLJ Ellacott, VL King, AH Hasty Disease models & mechanisms 3 (3-4), 156-166, 2010 | 345 | 2010 |
| Cross-talk between peroxisome proliferator-activated receptor (PPAR) α and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol … T Yoshikawa, T Ide, H Shimano, N Yahagi, M Amemiya-Kudo, ... Molecular Endocrinology 17 (7), 1240-1254, 2003 | 343 | 2003 |
| Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene M Amemiya-Kudo, H Shimano, T Yoshikawa, N Yahagi, AH Hasty, ... Journal of Biological Chemistry 275 (40), 31078-31085, 2000 | 299 | 2000 |
| Severe hypercholesterolemia, hypertriglyceridemia, and atherosclerosis in mice lacking both leptin and the low density lipoprotein receptor AH Hasty, H Shimano, J Osuga, I Namatame, A Takahashi, N Yahagi, ... Journal of Biological Chemistry 276 (40), 37402-37408, 2001 | 272 | 2001 |
| Impact of increased adipose tissue mass on inflammation, insulin resistance, and dyslipidemia DA Gutierrez, MJ Puglisi, AH Hasty Current diabetes reports 9 (1), 26-32, 2009 | 264 | 2009 |
| Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets T Kato, H Shimano, T Yamamoto, M Ishikawa, S Kumadaki, T Matsuzaka, ... Diabetes 57 (9), 2382-2392, 2008 | 257 | 2008 |
| A decade of progress in adipose tissue macrophage biology AA Hill, W Reid Bolus, AH Hasty Immunological reviews 262 (1), 134-152, 2014 | 253 | 2014 |
| Cloning and characterization of a mammalian fatty acyl-CoA elongase as a lipogenic enzyme regulated by SREBPs T Matsuzaka, H Shimano, N Yahagi, T Yoshikawa, M Amemiya-Kudo, ... Journal of lipid research 43 (6), 911-920, 2002 | 248 | 2002 |
| Insulin-independent induction of sterol regulatory element-binding protein-1c expression in the livers of streptozotocin-treated mice T Matsuzaka, H Shimano, N Yahagi, M Amemiya-Kudo, H Okazaki, ... Diabetes 53 (3), 560-569, 2004 | 241 | 2004 |
| Obesity induced by a high-fat diet is associated with increased immune cell entry into the central nervous system LB Buckman, AH Hasty, DK Flaherty, CT Buckman, MM Thompson, ... Brain, behavior, and immunity 35, 33-42, 2014 | 234 | 2014 |
Naoya YahagiAssociate Professor, Faculty of Medicine, University of TsukubaVerified email at umin.ac.jp
