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Thomas M Carlile
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Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells
TM Carlile, MF Rojas-Duran, B Zinshteyn, H Shin, KM Bartoli, WV Gilbert
Nature 515 (7525), 143-146, 2014
9282014
Meiosis I is established through division-specific translational control of a cyclin
TM Carlile, A Amon
Cell 133 (2), 280-291, 2008
2412008
Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis–emphysema
SE Stanley, DL Gable, CL Wagner, TM Carlile, VS Hanumanthu, ...
Science Translational Medicine 8 (351), 351ra107-351ra107, 2016
2032016
Regulated Formation of an Amyloid-like Translational Repressor Governs Gametogenesis
LE Berchowitz, G Kabachinski, MR Walker, TM Carlile, WV Gilbert, ...
Cell 163 (2), 406-418, 2015
1722015
mRNA structure determines modification by pseudouridine synthase 1
TM Carlile, NM Martinez, C Schaening, A Su, TA Bell, B Zinshteyn, ...
Nature chemical biology 15 (10), 966-974, 2019
1072019
Burkholderia cenocepacia phage BcepMu and a family of Mu-like phages encoding potential pathogenesis factors
EJ Summer, CF Gonzalez, T Carlisle, LM Mebane, AM Cass, CG Savva, ...
Journal of molecular biology 340 (1), 49-65, 2004
1052004
Aneuploid yeast strains exhibit defects in cell growth and passage through START
RR Thorburn, C Gonzalez, GA Brar, S Christen, TM Carlile, NT Ingolia, ...
Molecular biology of the cell 24 (9), 1274-1289, 2013
1022013
Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis
FG Lafaille, O Harschnitz, YS Lee, P Zhang, ML Hasek, G Kerner, Y Itan, ...
Nature Medicine 25 (12), 1873-1884, 2019
992019
Divergence and Mosaicism among Virulent Soil Phages of the Burkholderia cepacia Complex
EJ Summer, CF Gonzalez, M Bomer, T Carlile, A Embry, AM Kucherka, ...
Journal of Bacteriology 188 (1), 255-268, 2006
752006
Pseudo-Seq: genome-wide detection of pseudouridine modifications in RNA
TM Carlile, MF Rojas-Duran, WV Gilbert
Methods in enzymology 560, 219-245, 2015
592015
Genomes and characterization of phages Bcep22 and BcepIL02, founders of a novel phage type in Burkholderia cenocepacia
JJ Gill, EJ Summer, WK Russell, SM Cologna, TM Carlile, AC Fuller, ...
Journal of bacteriology 193 (19), 5300-5313, 2011
542011
Organotypic brain slice culture microglia exhibit molecular similarity to acutely-isolated adult microglia and provide a platform to study neuroinflammation
ARD Delbridge, D Huh, M Brickelmaier, JC Burns, C Roberts, R Challa, ...
Frontiers in cellular neuroscience 14, 592005, 2020
422020
MOG autoantibodies trigger a tightly-controlled FcR and BTK-driven microglia proliferative response
K Pellerin, SJ Rubino, JC Burns, BA Smith, CA McCarl, J Zhu, L Jandreski, ...
Brain 144 (8), 2361-2374, 2021
332021
Conserved Methyltransferase Spb1 Targets mRNAs for Regulated Modification with 2′-O-Methyl Ribose
KM Bartoli, C Schaening, T Carlile, WV Gilbert
bioRxiv, 271916, 2018
242018
Transcriptome‐Wide Identification of Pseudouridine Modifications Using Pseudo‐seq
TM Carlile, MF Rojas‐Duran, WV Gilbert
Current protocols in molecular biology 112 (1), 4.25. 1-4.25. 24, 2015
212015
Next‐generation Bruton's tyrosine kinase inhibitor BIIB091 selectively and potently inhibits B cell and Fc receptor signaling and downstream functions in B cells and myeloid cells
E Bame, H Tang, JC Burns, M Arefayene, K Michelsen, B Ma, I Marx, ...
Clinical & translational immunology 10 (6), e1295, 2021
172021
In vivo genome editing using novel AAV-PHP variants rescues motor function deficits and extends survival in a SOD1-ALS mouse model
YA Chen, MW Kankel, S Hana, SK Lau, MI Zavodszky, O McKissick, ...
Gene Therapy 30 (5), 443-454, 2023
72023
SCD Inhibition Protects from α-Synuclein-Induced Neurotoxicity But Is Toxic to Early Neuron Cultures
JW Nicholatos, J Groot, S Dhokai, D Tran, L Hrdlicka, TM Carlile, ...
Eneuro 8 (4), 2021
52021
Benchmarking and optimization of a high‐throughput sequencing based method for transgene sequence variant analysis in biotherapeutic cell line development
J Groot, Y Zhou, E Marshall, P Cullen, T Carlile, D Lin, CF Xu, J Crisafulli, ...
Biotechnology Journal 16 (8), 2000548, 2021
22021
Efficacy and safety of a SOD1-targeting artificial miRNA delivered by AAV9 in mice are impacted by miRNA scaffold selection
SK Chen, ZCE Hawley, MI Zavodszky, S Hana, D Ferretti, B Grubor, ...
Molecular Therapy-Nucleic Acids 34, 2023
12023
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