| A reversible and highly selective inhibitor of the proteasomal ubiquitin receptor rpn13 is toxic to multiple myeloma cells DJ Trader, S Simanski, T Kodadek Journal of the American Chemical Society 137 (19), 6312-6319, 2015 | 85 | 2015 |
| Integrated Metabolomics Approach Facilitates Discovery of an Unpredicted Natural Product Suite from Streptomyces coelicolor M145 AM Sidebottom, AR Johnson, JA Karty, DJ Trader, EE Carlson ACS chemical biology 8 (9), 2009-2016, 2013 | 80 | 2013 |
| Establishment of a suite of assays that support the discovery of proteasome stimulators DJ Trader, S Simanski, P Dickson, T Kodadek Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (4), 892-899, 2017 | 61 | 2017 |
| Chemoselective hydroxyl group transformation: an elusive target DJ Trader, EE Carlson Molecular BioSystems 8 (10), 2484-2493, 2012 | 59 | 2012 |
| Chemoselective enrichment for natural products discovery AY Odendaal, DJ Trader, EE Carlson Chemical science 2 (4), 760-764, 2011 | 48 | 2011 |
| Designing chimeric molecules for drug discovery by leveraging chemical biology C Borsari, DJ Trader, A Tait, MP Costi Journal of medicinal chemistry 63 (5), 1908-1928, 2020 | 43 | 2020 |
| Development and application of a sensitive peptide reporter to discover 20S proteasome stimulators RA Coleman, DJ Trader ACS Combinatorial Science 20 (5), 269-276, 2018 | 42 | 2018 |
| The immunoproteasome: an emerging target in cancer and autoimmune and neurological disorders BL Zerfas, ME Maresh, DJ Trader Journal of Medicinal Chemistry 63 (5), 1841-1858, 2019 | 41 | 2019 |
| Rubiscolins are naturally occurring G protein-biased delta opioid receptor peptides RJ Cassell, KL Mores, BL Zerfas, AH Mahmoud, MA Lill, DJ Trader, ... European Neuropsychopharmacology 29 (3), 450-456, 2019 | 35 | 2019 |
| Hyperexcitability and pharmacological responsiveness of cortical neurons derived from human iPSCs carrying epilepsy-associated sodium channel Nav1. 2-L1342P genetic variant Z Que, MI Olivero-Acosta, J Zhang, M Eaton, AM Tukker, X Chen, J Wu, ... Journal of Neuroscience 41 (49), 10194-10208, 2021 | 29 | 2021 |
| Siloxyl ether functionalized resins for chemoselective enrichment of carboxylic acids DJ Trader, EE Carlson Organic letters 13 (20), 5652-5655, 2011 | 29 | 2011 |
| Fluorescent probes with unnatural amino acids to monitor proteasome activity in real-time BL Zerfas, RA Coleman, AF Salazar-Chaparro, NJ Macatangay, ... ACS chemical biology 15 (9), 2588-2596, 2020 | 28 | 2020 |
| Monitoring the immunoproteasome in live cells using an activity-based peptide–peptoid hybrid probe BL Zerfas, DJ Trader Journal of the American Chemical Society 141 (13), 5252-5260, 2019 | 25 | 2019 |
| Analysis of chain length, substitution patterns, and unsaturation of AM-404 derivatives as 20S proteasome stimulators RA Coleman, CS Muli, Y Zhao, A Bhardwaj, TR Newhouse, DJ Trader Bioorganic & medicinal chemistry letters 29 (3), 420-423, 2019 | 24 | 2019 |
| All about the core: a therapeutic strategy to prevent protein accumulation with proteasome core particle stimulators RA Coleman, DJ Trader ACS Pharmacology & Translational Science 1 (2), 140-142, 2018 | 23 | 2018 |
| Taming of a superbase for selective phenol desilylation and natural product isolation DJ Trader, EE Carlson The Journal of organic chemistry 78 (14), 7349-7355, 2013 | 22 | 2013 |
| Methods to discover and evaluate proteasome small molecule stimulators RA Coleman, DJ Trader Molecules 24 (12), 2341, 2019 | 18 | 2019 |
| Protein degradation profile reveals dynamic nature of 20S proteasome small molecule stimulation RA Coleman, R Mohallem, UK Aryal, DJ Trader RSC Chemical Biology 2 (2), 636-644, 2021 | 13 | 2021 |
| Discovery of a small molecule probe of Rpn-6, an essential subunit of the 26S proteasome W Tian, DJ Trader ACS Chemical Biology 15 (2), 554-561, 2019 | 13 | 2019 |
| Small‐Molecule Inhibitors of the Proteasome's Regulatory Particle CS Muli, W Tian, DJ Trader ChemBioChem 20 (14), 1739-1753, 2019 | 12 | 2019 |
Ashley M. SidebottomPlatform Director DFI HMMF, The University of ChicagoVerified email at uchicago.edu
