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Kenneth C  Bedi Jr.
Kenneth C Bedi Jr.
Verified email at pennmedicine.upenn.edu
Title
Cited by
Cited by
Year
Evidence for intramyocardial disruption of lipid metabolism and increased myocardial ketone utilization in advanced human heart failure
KC Bedi Jr, NW Snyder, J Brandimarto, M Aziz, C Mesaros, AJ Worth, ...
Circulation 133 (8), 706-716, 2016
5322016
Targeting cardiac fibrosis with engineered T cells
H Aghajanian, T Kimura, JG Rurik, AS Hancock, MS Leibowitz, L Li, ...
Nature 573 (7774), 430-433, 2019
4872019
Transcriptional and cellular diversity of the human heart
NR Tucker, M Chaffin, SJ Fleming, AW Hall, VA Parsons, KC Bedi Jr, ...
Circulation 142 (5), 466-482, 2020
3572020
Suppression of detyrosinated microtubules improves cardiomyocyte function in human heart failure
CY Chen, MA Caporizzo, K Bedi, A Vite, AI Bogush, P Robison, JG Heffler, ...
Nature medicine 24 (8), 1225-1233, 2018
2122018
Mitochondrial protein hyperacetylation in the failing heart
JL Horton, OJ Martin, L Lai, NM Riley, AL Richards, RB Vega, TC Leone, ...
JCI insight 1 (2), 2016
2052016
Myocardial gene expression signatures in human heart failure with preserved ejection fraction
VS Hahn, H Knutsdottir, X Luo, K Bedi, KB Margulies, SM Haldar, ...
Circulation 143 (2), 120-134, 2021
1502021
Single-nucleus profiling of human dilated and hypertrophic cardiomyopathy
M Chaffin, I Papangeli, B Simonson, AD Akkad, MC Hill, A Arduini, ...
Nature 608 (7921), 174-180, 2022
1372022
Myocyte-Specific Upregulation of ACE2 in Cardiovascular Disease: Implications for SARS-CoV-2–Mediated Myocarditis
NR Tucker, M Chaffin, KC Bedi Jr, I Papangeli, AD Akkad, A Arduini, ...
Circulation 142 (7), 708-710, 2020
1102020
Cardiomyocyte‐specific telomere shortening is a distinct signature of heart failure in humans
M Sharifi‐Sanjani, NM Oyster, ED Tichy, KC Bedi Jr, O Harel, ...
Journal of the American Heart Association 6 (9), e005086, 2017
962017
C-type natriuretic peptide co-ordinates cardiac structure and function
AJ Moyes, SM Chu, AA Aubdool, MS Dukinfield, KB Margulies, KC Bedi Jr, ...
European heart journal 41 (9), 1006-1020, 2020
702020
Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes
PP Shah, W Lv, JH Rhoades, A Poleshko, D Abbey, MA Caporizzo, ...
Cell Stem Cell 28 (5), 938-954. e9, 2021
692021
Nuclear deformation guides chromatin reorganization in cardiac development and disease
B Seelbinder, S Ghosh, SE Schneider, AK Scott, AG Berman, CJ Goergen, ...
Nature biomedical engineering 5 (12), 1500-1516, 2021
512021
Truncated titin proteins in dilated cardiomyopathy
Q McAfee, CY Chen, Y Yang, MA Caporizzo, M Morley, A Babu, S Jeong, ...
Science translational medicine 13 (618), eabd7287, 2021
472021
Quantitative subcellular acyl-CoA analysis reveals distinct nuclear metabolism and isoleucine-dependent histone propionylation
S Trefely, K Huber, J Liu, M Noji, S Stransky, J Singh, MT Doan, CD Lovell, ...
Molecular cell 82 (2), 447-462. e6, 2022
462022
Myocardial metabolomics of human heart failure with preserved ejection fraction
VS Hahn, C Petucci, MS Kim, KC Bedi Jr, H Wang, S Mishra, N Koleini, ...
Circulation 147 (15), 1147-1161, 2023
452023
Depletion of vasohibin 1 speeds contraction and relaxation in failing human cardiomyocytes
CY Chen, AK Salomon, MA Caporizzo, S Curry, NA Kelly, K Bedi, ...
Circulation research 127 (2), e14-e27, 2020
382020
Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure
D Murashige, JW Jung, MD Neinast, MG Levin, Q Chu, JP Lambert, ...
Cell metabolism 34 (11), 1749-1764. e7, 2022
332022
Integrated landscape of cardiac metabolism in end-stage human nonischemic dilated cardiomyopathy
E Flam, C Jang, D Murashige, Y Yang, MP Morley, S Jung, DS Kantner, ...
Nature cardiovascular research 1 (9), 817-829, 2022
322022
S-nitrosylation of histone deacetylase 2 by neuronal nitric oxide synthase as a mechanism of diastolic dysfunction
S Yoon, M Kim, H Lee, G Kang, K Bedi, KB Margulies, R Jain, KI Nam, ...
Circulation 143 (19), 1912-1925, 2021
302021
Cardiomyocyte d-dopachrome tautomerase protects against heart failure
Y Ma, KN Su, D Pfau, VS Rao, X Wu, X Hu, L Leng, X Du, M Piecychna, ...
JCI insight 4 (17), 2019
282019
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