| Structure-based discovery of nonopioid analgesics acting through the α2A-adrenergic receptor EA Fink, J Xu, H Hübner, JM Braz, P Seemann, C Avet, V Craik, D Weikert, ... Science 377 (6614), eabn7065, 2022 | 65 | 2022 |
| Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer K Bhuripanyo, Y Wang, X Liu, L Zhou, R Liu, D Duong, B Zhao, Y Bi, ... Science advances 4 (1), e1701393, 2018 | 48 | 2018 |
| Predicting mutational effects on receptor binding of the spike protein of SARS-CoV-2 variants C Bai, J Wang, G Chen, H Zhang, K An, P Xu, Y Du, RD Ye, A Saha, ... Journal of the American Chemical Society 143 (42), 17646-17654, 2021 | 44 | 2021 |
| Structural basis for recognition of N-formyl peptides as pathogen-associated molecular patterns G Chen, X Wang, Q Liao, Y Ge, H Jiao, Q Chen, Y Liu, W Lyu, L Zhu, ... Nature communications 13 (1), 5232, 2022 | 23 | 2022 |
| Activation and allosteric regulation of the orphan GPR88-Gi1 signaling complex G Chen, J Xu, A Inoue, MF Schmidt, C Bai, Q Lu, P Gmeiner, Z Liu, Y Du Nature communications 13 (1), 2375, 2022 | 16 | 2022 |
| Structural insights into ligand recognition, activation, and signaling of the α2A adrenergic receptor J Xu, S Cao, H Hübner, D Weikert, G Chen, Q Lu, D Yuan, P Gmeiner, ... Science advances 8 (9), eabj5347, 2022 | 15 | 2022 |
| G protein-coupled receptors in neurodegenerative diseases and psychiatric disorders TS Wong, G Li, S Li, W Gao, G Chen, S Gan, M Zhang, H Li, S Wu, Y Du Signal Transduction and Targeted Therapy 8 (1), 177, 2023 | 14 | 2023 |
| Cryo-EM structure of activated bile acids receptor TGR5 in complex with stimulatory G protein G Chen, X Wang, Y Ge, L Ma, Q Chen, H Liu, Y Du, RD Ye, H Hu, R Ren Signal Transduction and Targeted Therapy 5 (1), 142, 2020 | 13 | 2020 |
| Cryo‐EM structure of G‐protein‐coupled receptor GPR17 in complex with inhibitory G protein F Ye, TS Wong, G Chen, Z Zhang, B Zhang, S Gan, W Gao, J Li, Z Wu, ... MedComm 3 (4), e159, 2022 | 12 | 2022 |
| Regulation of the endocytosis and prion-chaperoning machineries by yeast E3 ubiquitin ligase Rsp5 as revealed by orthogonal ubiquitin transfer Y Wang, S Fang, G Chen, R Ganti, TA Chernova, L Zhou, D Duong, ... Cell chemical biology 28 (9), 1283-1297. e8, 2021 | 10 | 2021 |
| Calcineurin-fusion facilitates Cryo-EM structure determination of a family A GPCR J Xu, G Chen, H Wang, S Cao, J Heng, X Deupi, Y Du, BK Kobilka BioRxiv, 2022.03. 27.485993, 2022 | 9 | 2022 |
| Cryo‐EM structure of orphan G protein‐coupled receptor GPR21 TS Wong, W Gao, G Chen, C Qiu, G He, F Ye, Z Wu, Z Zeng, Y Du MedComm 4 (1), e205, 2023 | 7 | 2023 |
| Cryo-EM structure of the human chemerin receptor 1–Gi protein complex bound to the C-terminal nonapeptide of chemerin J Wang, G Chen, Q Liao, W Lyu, A Liu, L Zhu, Y Du, RD Ye Proceedings of the National Academy of Sciences 120 (11), e2214324120, 2023 | 6 | 2023 |
| Structural and functional characterization of the endogenous agonist for orphan receptor GPR3 G Chen, N Staffen, Z Wu, X Xu, J Pan, A Inoue, T Shi, P Gmeiner, Y Du, ... Cell Research, 1-4, 2024 | 1 | 2024 |
| Structural insights into ligand recognition and selectivity of the human hydroxycarboxylic acid receptor HCAR2 X Pan, F Ye, P Ning, Z Zhang, X Li, B Zhang, Q Wang, G Chen, W Gao, ... Cell Discovery 9 (1), 118, 2023 | 1 | 2023 |
| Profiling and verifying the substrates of E3 ubiquitin ligase Rsp5 in yeast cells S Fang, G Chen, Y Wang, R Ganti, TA Chernova, L Zhou, SE Jacobs, ... STAR protocols 4 (3), 102489, 2023 | 1 | 2023 |
| Identification of a Sialosides binding pocket in early-lineage SARS-CoV-2 via an optimized STD NMR method: a novel explanation for coronavirus virulence and zoonosis G Chen, W Gao, Y Du Molecular Biomedicine 3 (1), 32, 2022 | | 2022 |
Yang DuThe Chinese University of Hong Kong, ShenzhenVerified email at cuhk.edu.cn
