| Compound Optimization in Early- and Late-Phase Drug Discovery: Physiochemical, Pharmacokinetic, Drug Metabolism and Toxicologic Assessments - Editor - Volume 1(4) GW Caldwell Current Topics in Medicinal Chemistry 1 (4), 233-351, 2001 | 882* | 2001 |
| Compound Optimization in Early- and Late-Phase Drug Discovery: Physiochemical, Pharmacokinetic, Drug Metabolism and Toxicologic Assessments - Editor - Volume 1(5) GW Caldwell Current Topics in Medicinal Chemistry 1 (5), 353-471, 2001 | 582* | 2001 |
| Methods in pharmacology and toxicology: Optimization in Drug Discovery: In vitro Methods - Volume 1 - Editor Z Yan, GW Caldwell New Jersey: Humana Press 1, 1-404, 2004 | 330* | 2004 |
| Metabolism profiling, and cytochrome P450 inhibition & induction in drug discovery Z Yan, GW Caldwell Current topics in medicinal chemistry 1 (5), 403-425, 2001 | 250 | 2001 |
| Frontiers in Drug Design and Discovery V3- Editor GW Caldwell, Atta-ur-Rahman, MR Player, MI Chowdhary Bentham Science Publishers 3, 1-610, 2007 | 249* | 2007 |
| SN2 reactions in the gas phase. Temperature dependence of the rate constants and energies of the transition states. Comparison with solution G Caldwell, TF Magnera, P Kebarle Journal of the American Chemical Society 106 (4), 959-966, 1984 | 214 | 1984 |
| The new pre-preclinical paradigm: compound optimization in early and late phase drug discovery GW Caldwell, DM Ritchie, JA Masucci, W Hageman, Z Yan Current topics in medicinal chemistry 1 (5), 353-366, 2001 | 200 | 2001 |
| Methods in Pharmacology and Toxicology, Optimization in Drug Discovery: In Vitro Methods -Volume 2 - Editor GW Caldwell, Z Yan Springer 2, 1-592, 2014 | 184* | 2014 |
| Gas phase acidities of aliphatic carboxylic acids, based on measurements of proton transfer equilibria G Caldwell, R Renneboog, P Kebarle Canadian Journal of Chemistry 67 (4), 611-618, 1989 | 171 | 1989 |
| Stable-isotope trapping and high-throughput screenings of reactive metabolites using the isotope MS signature Z Yan, GW Caldwell Analytical Chemistry 76 (23), 6835-6847, 2004 | 165 | 2004 |
| Metabolomics - Editor GW Caldwell Current topics in medicinal chemistry 17 (24), 2715-2715, 2017 | 163* | 2017 |
| Frontiers in Drug Design & Discovery V1- Editor GW Caldwell, Atta-ur-Rahman, BA Springer Bentham Science Publishers 1, 1-347, 2005 | 154* | 2005 |
| Allometric scaling of pharmacokinetic parameters in drug discovery: Can human CL, Vss and t1/2 be predicted fromin-vivo rat data? GW Caldwell, JA Masucci, Z Yan, W Hageman European journal of drug metabolism and pharmacokinetics 29, 133-143, 2004 | 134 | 2004 |
| The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and-2 J Qi, W Lang, JG Geisler, P Wang, I Petrounia, S Mai, C Smith, H Askari, ... Journal of lipid research 53 (6), 1106-1116, 2012 | 128 | 2012 |
| Electron affinities from electron-transfer equilibria: A-+ B= A+ B EP Grimsrud, G Caldwell, S Chowdhury, P Kebarle Journal of the American Chemical Society 107 (16), 4627-4634, 1985 | 127 | 1985 |
| [99mTc] tricine: a useful precursor complex for the radiolabeling of hydrazinonicotinate protein conjugates SK Larsen, HF Solomon, G Caldwell, MJ Abrams Bioconjugate chemistry 6 (5), 635-638, 1995 | 121 | 1995 |
| Detection of a novel reactive metabolite of diclofenac: evidence for CYP2C9-mediated bioactivation via arene oxides Z Yan, J Li, N Huebert, GW Caldwell, Y Du, H Zhong Drug Metabolism and Disposition 33 (6), 706-713, 2005 | 109 | 2005 |
| Compound optimization in early-and late-phase drug discovery: acceptable pharmacokinetic properties utilizing combined physicochemical, in vitro and in vivo screens GW Caldwell Current Opinion in Drug Discovery and Development 3 (1), 30-41, 2000 | 107 | 2000 |
| Evaluation of the immobilized artificial membrane phosphatidylcholine: Drug discovery column for high-performance liquid chromatographic screening of drug–membrane interactions GW Caldwell, JA Masucci, M Evangelisto, R White Journal of Chromatography A 800 (2), 161-169, 1998 | 99 | 1998 |
| The hydrogen bond energies of the bihalide ions XHX− and YHX− G Caldwell, P Kebarle Canadian journal of chemistry 63 (7), 1399-1406, 1985 | 96 | 1985 |
John A. MasucciJanssen Research and Development, LLCVerified email at its.jnj.com
