Structure of the HIV-1 RNA packaging signal SC Keane, X Heng, K Lu, S Kharytonchyk, V Ramakrishnan, G Carter, ... Science 348 (6237), 917-921, 2015 | 283 | 2015 |
Coronavirus N protein N-terminal domain (NTD) specifically binds the transcriptional regulatory sequence (TRS) and melts TRS-cTRS RNA duplexes NE Grossoehme, L Li, SC Keane, P Liu, CE Dann III, JL Leibowitz, ... Journal of molecular biology 394 (3), 544-557, 2009 | 155 | 2009 |
Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences JL Meagher, M Takata, D Gonçalves-Carneiro, SC Keane, A Rebendenne, ... Proceedings of the National Academy of Sciences 116 (48), 24303-24309, 2019 | 116 | 2019 |
Structure of the 30 kDa HIV-1 RNA dimerization signal by a hybrid cryo-EM, NMR, and molecular dynamics approach K Zhang, SC Keane, Z Su, RN Irobalieva, M Chen, V Van, CA Sciandra, ... Structure 26 (3), 490-498. e3, 2018 | 64 | 2018 |
NMR detection of intermolecular interaction sites in the dimeric 5′-leader of the HIV-1 genome SC Keane, V Van, HM Frank, CA Sciandra, S McCowin, J Santos, X Heng, ... Proceedings of the National Academy of Sciences 113 (46), 13033-13038, 2016 | 61 | 2016 |
Functional transcriptional regulatory sequence (TRS) RNA binding and helix destabilizing determinants of murine hepatitis virus (MHV) nucleocapsid (N) protein SC Keane, P Liu, JL Leibowitz, DP Giedroc Journal of Biological Chemistry 287 (10), 7063-7073, 2012 | 60 | 2012 |
Mouse hepatitis virus stem-loop 2 adopts a uYNMG (U) a-like tetraloop structure that is highly functionally tolerant of base substitutions P Liu, L Li, SC Keane, D Yang, JL Leibowitz, DP Giedroc Journal of virology 83 (23), 12084-12093, 2009 | 54 | 2009 |
Regio‐selective chemical‐enzymatic synthesis of pyrimidine nucleotides facilitates RNA structure and dynamics studies LJ Alvarado, RM LeBlanc, AP Longhini, SC Keane, N Jain, ZF Yildiz, ... ChemBioChem 15 (11), 1573-1577, 2014 | 52 | 2014 |
NMR studies of the structure and function of the HIV-1 5′-leader SC Keane, MF Summers Viruses 8 (12), 338, 2016 | 49 | 2016 |
Solution structure of mouse hepatitis virus (MHV) nsp3a and determinants of the interaction with MHV nucleocapsid (N) protein SC Keane, DP Giedroc Journal of virology 87 (6), 3502-3515, 2013 | 47 | 2013 |
Reconstitution of selective HIV-1 RNA packaging in vitro by membrane-bound Gag assemblies LA Carlson, Y Bai, SC Keane, JA Doudna, JH Hurley Elife 5, e14663, 2016 | 46 | 2016 |
Advanced approaches for elucidating structures of large RNAs using NMR spectroscopy and complementary methods A Kotar, HN Foley, KM Baughman, SC Keane Methods 183, 93-107, 2020 | 36 | 2020 |
Advances that facilitate the study of large RNA structure and dynamics by nuclear magnetic resonance spectroscopy H Zhang, SC Keane Wiley Interdisciplinary Reviews: RNA 10 (5), e1541, 2019 | 36 | 2019 |
Anomalous reverse transcription through chemical modifications in polyadenosine stretches W Kladwang, VV Topkar, B Liu, R Rangan, TL Hodges, SC Keane, ... Biochemistry 59 (23), 2154-2170, 2020 | 10 | 2020 |
NMR chemical shift assignments of RNA oligonucleotides to expand the RNA chemical shift database Y Liu, A Kotar, TL Hodges, K Abdallah, MH Taleb, BA Bitterman, S Jaime, ... Biomolecular NMR Assignments 15 (2), 479-490, 2021 | 7 | 2021 |
pH dependence of C• A, G• A and A• A mismatches in the stem of precursor microRNA-31 A Kotar, S Ma, SC Keane Biophysical chemistry 283, 106763, 2022 | 6 | 2022 |
Solution structure of NPSL2, a regulatory element in the oncomiR-1 RNA Y Liu, A Munsayac, I Hall, SC Keane Journal of molecular biology 434 (18), 167688, 2022 | 4 | 2022 |
A tale of two transitions: The unfolding mechanism of the prfA RNA thermosensor H Zhang, I Hall, AJ Nissley, K Abdallah, SC Keane Biochemistry 59 (48), 4533-4545, 2020 | 4 | 2020 |
Structure of pre-miR-31 reveals an active role in Dicer–TRBP complex processing S Ma, A Kotar, I Hall, S Grote, S Rouskin, SC Keane Proceedings of the National Academy of Sciences 120 (39), e2300527120, 2023 | 2 | 2023 |
1H, 13C, 15N resonance assignments of murine hepatitis virus nonstructural protein 3a SC Keane, DP Giedroc Biomolecular NMR assignments 8, 15-17, 2014 | 2 | 2014 |