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Sarah C Keane
Sarah C Keane
Verified email at umich.edu
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Year
Structure of the HIV-1 RNA packaging signal
SC Keane, X Heng, K Lu, S Kharytonchyk, V Ramakrishnan, G Carter, ...
Science 348 (6237), 917-921, 2015
2832015
Coronavirus N protein N-terminal domain (NTD) specifically binds the transcriptional regulatory sequence (TRS) and melts TRS-cTRS RNA duplexes
NE Grossoehme, L Li, SC Keane, P Liu, CE Dann III, JL Leibowitz, ...
Journal of molecular biology 394 (3), 544-557, 2009
1552009
Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences
JL Meagher, M Takata, D Gonçalves-Carneiro, SC Keane, A Rebendenne, ...
Proceedings of the National Academy of Sciences 116 (48), 24303-24309, 2019
1162019
Structure of the 30 kDa HIV-1 RNA dimerization signal by a hybrid cryo-EM, NMR, and molecular dynamics approach
K Zhang, SC Keane, Z Su, RN Irobalieva, M Chen, V Van, CA Sciandra, ...
Structure 26 (3), 490-498. e3, 2018
642018
NMR detection of intermolecular interaction sites in the dimeric 5′-leader of the HIV-1 genome
SC Keane, V Van, HM Frank, CA Sciandra, S McCowin, J Santos, X Heng, ...
Proceedings of the National Academy of Sciences 113 (46), 13033-13038, 2016
612016
Functional transcriptional regulatory sequence (TRS) RNA binding and helix destabilizing determinants of murine hepatitis virus (MHV) nucleocapsid (N) protein
SC Keane, P Liu, JL Leibowitz, DP Giedroc
Journal of Biological Chemistry 287 (10), 7063-7073, 2012
602012
Mouse hepatitis virus stem-loop 2 adopts a uYNMG (U) a-like tetraloop structure that is highly functionally tolerant of base substitutions
P Liu, L Li, SC Keane, D Yang, JL Leibowitz, DP Giedroc
Journal of virology 83 (23), 12084-12093, 2009
542009
Regio‐selective chemical‐enzymatic synthesis of pyrimidine nucleotides facilitates RNA structure and dynamics studies
LJ Alvarado, RM LeBlanc, AP Longhini, SC Keane, N Jain, ZF Yildiz, ...
ChemBioChem 15 (11), 1573-1577, 2014
522014
NMR studies of the structure and function of the HIV-1 5′-leader
SC Keane, MF Summers
Viruses 8 (12), 338, 2016
492016
Solution structure of mouse hepatitis virus (MHV) nsp3a and determinants of the interaction with MHV nucleocapsid (N) protein
SC Keane, DP Giedroc
Journal of virology 87 (6), 3502-3515, 2013
472013
Reconstitution of selective HIV-1 RNA packaging in vitro by membrane-bound Gag assemblies
LA Carlson, Y Bai, SC Keane, JA Doudna, JH Hurley
Elife 5, e14663, 2016
462016
Advanced approaches for elucidating structures of large RNAs using NMR spectroscopy and complementary methods
A Kotar, HN Foley, KM Baughman, SC Keane
Methods 183, 93-107, 2020
362020
Advances that facilitate the study of large RNA structure and dynamics by nuclear magnetic resonance spectroscopy
H Zhang, SC Keane
Wiley Interdisciplinary Reviews: RNA 10 (5), e1541, 2019
362019
Anomalous reverse transcription through chemical modifications in polyadenosine stretches
W Kladwang, VV Topkar, B Liu, R Rangan, TL Hodges, SC Keane, ...
Biochemistry 59 (23), 2154-2170, 2020
102020
NMR chemical shift assignments of RNA oligonucleotides to expand the RNA chemical shift database
Y Liu, A Kotar, TL Hodges, K Abdallah, MH Taleb, BA Bitterman, S Jaime, ...
Biomolecular NMR Assignments 15 (2), 479-490, 2021
72021
pH dependence of C• A, G• A and A• A mismatches in the stem of precursor microRNA-31
A Kotar, S Ma, SC Keane
Biophysical chemistry 283, 106763, 2022
62022
Solution structure of NPSL2, a regulatory element in the oncomiR-1 RNA
Y Liu, A Munsayac, I Hall, SC Keane
Journal of molecular biology 434 (18), 167688, 2022
42022
A tale of two transitions: The unfolding mechanism of the prfA RNA thermosensor
H Zhang, I Hall, AJ Nissley, K Abdallah, SC Keane
Biochemistry 59 (48), 4533-4545, 2020
42020
Structure of pre-miR-31 reveals an active role in Dicer–TRBP complex processing
S Ma, A Kotar, I Hall, S Grote, S Rouskin, SC Keane
Proceedings of the National Academy of Sciences 120 (39), e2300527120, 2023
22023
1H, 13C, 15N resonance assignments of murine hepatitis virus nonstructural protein 3a
SC Keane, DP Giedroc
Biomolecular NMR assignments 8, 15-17, 2014
22014
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