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Leif Smith
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Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature
PG Arnison, MJ Bibb, G Bierbaum, AA Bowers, TS Bugni, G Bulaj, ...
Natural product reports 30 (1), 108-160, 2013
20172013
An alternative bactericidal mechanism of action for lantibiotic peptides that target lipid II
HE Hasper, NE Kramer, JL Smith, JD Hillman, C Zachariah, OP Kuipers, ...
Science 313 (5793), 1636-1637, 2006
6022006
Occidiofungin, a Unique Antifungal Glycopeptide Produced by a Strain of Burkholderia contaminans
SE Lu, J Novak, FW Austin, G Gu, D Ellis, M Kirk, S Wilson-Stanford, ...
Biochemistry 48 (35), 8312-8321, 2009
1492009
Therapeutic potential of type A (I) lantibiotics, a group of cationic peptide antibiotics
L Smith, JD Hillman
Current opinion in microbiology 11 (5), 401-408, 2008
1022008
Oxidation of lanthionines renders the lantibiotic nisin inactive
S Wilson-Stanford, A Kalli, K Håkansson, J Kastrantas, RS Orugunty, ...
Applied and Environmental Microbiology 75 (5), 1381-1387, 2009
882009
Elucidation of the antimicrobial mechanism of mutacin 1140
L Smith, H Hasper, E Breukink, J Novak, J Čerkasov, JD Hillman, ...
Biochemistry 47 (10), 3308-3314, 2008
872008
Two flavoenzymes catalyze the post-translational generation of 5-chlorotryptophan and 2-aminovinyl-cysteine during NAI-107 biosynthesis
MA Ortega, DP Cogan, S Mukherjee, N Garg, B Li, GN Thibodeaux, ...
ACS chemical biology 12 (2), 548-557, 2017
832017
Biosynthesis of an antifungal oligopeptide in Burkholderia contaminans strain MS14
G Gu, L Smith, N Wang, H Wang, SE Lu
Biochemical and biophysical research communications 380 (2), 328-332, 2009
742009
Genetic and biochemical map for the biosynthesis of occidiofungin, an antifungal produced by Burkholderia contaminans strain MS14
G Gu, L Smith, A Liu, SE Lu
Applied and Environmental Microbiology 77 (17), 6189-6198, 2011
732011
Structure and dynamics of the lantibiotic mutacin 1140
L Smith, C Zachariah, R Thirumoorthy, J Rocca, J Novák, JD Hillman, ...
Biochemistry 42 (35), 10372-10384, 2003
682003
Covalent structure of mutacin 1140 and a novel method for the rapid identification of lantibiotics
L Smith, J Novák, J Rocca, S McClung, JD Hillman, AS Edison
European journal of biochemistry 267 (23), 6810-6816, 2000
652000
Evolution of lantibiotic salivaricins: new weapons to fight infectious diseases
A Barbour, P Wescombe, L Smith
Trends in microbiology 28 (7), 578-593, 2020
562020
Site-directed mutations in the lanthipeptide mutacin 1140
S Chen, S Wilson-Stanford, W Cromwell, JD Hillman, A Guerrero, ...
Applied and environmental microbiology 79 (13), 4015-4023, 2013
562013
Comparative genome‐wide analysis reveals that Burkholderia contaminans MS14 possesses multiple antimicrobial biosynthesis genes but not major genetic loci …
P Deng, X Wang, SM Baird, KC Showmaker, L Smith, DG Peterson, S Lu
Microbiologyopen 5 (3), 353-369, 2016
542016
Occidiofungin's Chemical Stability and In Vitro Potency against Candida Species
D Ellis, J Gosai, C Emrick, R Heintz, L Romans, D Gordon, SE Lu, F Austin, ...
Antimicrobial agents and chemotherapy 56 (2), 765-769, 2012
542012
The antifungal occidiofungin triggers an apoptotic mechanism of cell death in yeast
D Emrick, A Ravichandran, J Gosai, S Lu, DM Gordon, L Smith
Journal of natural products 76 (5), 829-838, 2013
532013
IA3, an Aspartic Proteinase Inhibitor from Saccharomyces cerevisiae, Is Intrinsically Unstructured in Solution
TB Green, O Ganesh, K Perry, L Smith, LH Phylip, TM Logan, SJ Hagen, ...
Biochemistry 43 (14), 4071-4081, 2004
512004
AmbR1 is a key transcriptional regulator for production of antifungal activity of Burkholderia contaminans strain MS14
G Gu, N Wang, N Chaney, L Smith, SE Lu
FEMS microbiology letters 297 (1), 54-60, 2009
422009
Occidiofungin is an important component responsible for the antifungal activity of Burkholderia pyrrocinia strain Lyc2
XQ Wang, AX Liu, A Guerrero, J Liu, XQ Yu, P Deng, L Ma, SM Baird, ...
Journal of applied microbiology 120 (3), 607-618, 2016
412016
A Novel Actin Binding Drug with In Vivo Efficacy
A Ravichandran, M Geng, KG Hull, J Li, D Romo, SE Lu, A Albee, C Nutter, ...
Antimicrobial agents and chemotherapy 63 (1), 10.1128/aac. 01585-18, 2019
342019
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