Detection of a low-grade enteroviral infection in the islets of langerhans of living patients newly diagnosed with type 1 diabetes L Krogvold, B Edwin, T Buanes, G Frisk, O Skog, M Anagandula, ... Diabetes 64 (5), 1682-1687, 2015 | 347 | 2015 |
Differential insulitic profiles determine the extent of β-cell destruction and the age at onset of type 1 diabetes P Leete, A Willcox, L Krogvold, K Dahl-Jørgensen, AK Foulis, ... Diabetes 65 (5), 1362-1369, 2016 | 298 | 2016 |
Islet cell hyperexpression of HLA class I antigens: a defining feature in type 1 diabetes SJ Richardson, T Rodriguez-Calvo, IC Gerling, CE Mathews, JS Kaddis, ... Diabetologia 59 (11), 2448-2458, 2016 | 283 | 2016 |
Blood and islet phenotypes indicate immunological heterogeneity in type 1 diabetes S Arif, P Leete, V Nguyen, K Marks, NM Nor, M Estorninho, ... Diabetes 63 (11), 3835-3845, 2014 | 232 | 2014 |
PDL1 is expressed in the islets of people with type 1 diabetes and is up-regulated by interferons-α and-γ via IRF1 induction ML Colli, JLE Hill, L Marroquí, J Chaffey, RS Dos Santos, P Leete, ... EBioMedicine 36, 367-375, 2018 | 158 | 2018 |
Expression of the enteroviral capsid protein VP1 in the islet cells of patients with type 1 diabetes is associated with induction of protein kinase R and downregulation of Mcl-1 SJ Richardson, P Leete, AJ Bone, AK Foulis, NG Morgan Diabetologia 56, 185-193, 2013 | 151 | 2013 |
Studies of insulin and proinsulin in pancreas and serum support the existence of aetiopathological endotypes of type 1 diabetes associated with age at diagnosis P Leete, RA Oram, TJ McDonald, BM Shields, C Ziller, ... Diabetologia 63, 1258-1267, 2020 | 122 | 2020 |
HLA class II antigen processing and presentation pathway components demonstrated by transcriptome and protein analyses of islet β-cells from donors with type 1 diabetes MA Russell, SD Redick, DM Blodgett, SJ Richardson, P Leete, L Krogvold, ... Diabetes 68 (5), 988-1001, 2019 | 108 | 2019 |
C-peptide decline in type 1 diabetes has two phases: an initial exponential fall and a subsequent stable phase BM Shields, TJ McDonald, R Oram, A Hill, M Hudson, P Leete, ... Diabetes care 41 (7), 1486-1492, 2018 | 103 | 2018 |
Abnormal neutrophil signature in the blood and pancreas of presymptomatic and symptomatic type 1 diabetes F Vecchio, NL Buono, A Stabilini, L Nigi, MJ Dufort, S Geyer, PM Rancoita, ... JCI insight 3 (18), 2018 | 92 | 2018 |
Islet inflammation in human type 1 diabetes mellitus NG Morgan, P Leete, AK Foulis, SJ Richardson IUBMB life 66 (11), 723-734, 2014 | 83 | 2014 |
Unexpected subcellular distribution of a specific isoform of the Coxsackie and adenovirus receptor, CAR-SIV, in human pancreatic beta cells E Ifie, MA Russell, S Dhayal, P Leete, G Sebastiani, L Nigi, F Dotta, ... Diabetologia 61, 2344-2355, 2018 | 71 | 2018 |
Induction of an antiviral state and attenuated coxsackievirus replication in type III interferon-treated primary human pancreatic islets K Lind, SJ Richardson, P Leete, NG Morgan, O Korsgren, ... Journal of virology 87 (13), 7646-7654, 2013 | 53 | 2013 |
The effect of age on the progression and severity of type 1 diabetes: potential effects on disease mechanisms P Leete, R Mallone, SJ Richardson, JM Sosenko, MJ Redondo, ... Current diabetes reports 18, 1-8, 2018 | 46 | 2018 |
Evaluation of the fidelity of immunolabelling obtained with clone 5D8/1, a monoclonal antibody directed against the enteroviral capsid protein, VP1, in human pancreas SJ Richardson, P Leete, S Dhayal, MA Russell, M Oikarinen, JE Laiho, ... Diabetologia 57, 392-401, 2014 | 38 | 2014 |
Altered β-cell prohormone processing and secretion in type 1 diabetes T Rodriguez-Calvo, YC Chen, CB Verchere, L Haataja, P Arvan, P Leete, ... Diabetes 70 (5), 1038-1050, 2021 | 25 | 2021 |
Detection of antiviral tissue responses and increased cell stress in the pancreatic islets of newly diagnosed type 1 diabetes patients: results from the DiViD study L Krogvold, P Leete, IM Mynarek, MA Russell, IC Gerling, NI Lenchik, ... Frontiers in Endocrinology 13, 881997, 2022 | 14 | 2022 |
Circulating C-peptide levels in living children and young people and pancreatic β-cell loss in pancreas donors across type 1 diabetes disease duration ALJ Carr, JRJ Inshaw, CS Flaxman, P Leete, RC Wyatt, LA Russell, ... Diabetes 71 (7), 1591-1596, 2022 | 14 | 2022 |
Detection of enterovirus in the islet cells of patients with type 1 diabetes: what do we learn from immunohistochemistry? Reply to Hansson SF, Korsgren S, Pontén F et al SJ Richardson, P Leete, S Dhayal, MA Russell, M Oikarinen, JE Laiho, ... Diabetologia 57, 647-649, 2014 | 12 | 2014 |
Footprints of immune cells in the pancreas in type 1 diabetes; to “B” or not to “B”: is that still the question? P Leete, NG Morgan Frontiers in Endocrinology 12, 617437, 2021 | 11 | 2021 |