The m6A RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor Y Xiao, KN Thakkar, H Zhao, J Broughton, Y Li, JA Seoane, AN Diep, ... Proceedings of the National Academy of Sciences 117 (35), 21441-21449, 2020 | 75 | 2020 |
Establishment of peripheral blood mononuclear cell-derived humanized lung cancer mouse models for studying efficacy of PD-L1/PD-1 targeted immunotherapy S Lin, G Huang, L Cheng, Z Li, Y Xiao, Q Deng, Y Jiang, B Li, S Lin, ... MAbs 10 (8), 1301-1311, 2018 | 71 | 2018 |
Metabolic profiling reveals a dependency of human metastatic breast cancer on mitochondrial serine and one-carbon unit metabolism AM Li, GS Ducker, Y Li, JA Seoane, Y Xiao, S Melemenidis, Y Zhou, L Liu, ... Molecular Cancer Research 18 (4), 599-611, 2022 | 70 | 2022 |
Cancer-associated mesothelial cells promote ovarian cancer chemoresistance through paracrine osteopontin signaling J Qian, BL LeSavage, KM Hubka, C Ma, S Natarajan, JT Eggold, Y Xiao, ... The Journal of Clinical Investigation 131 (16), 2021 | 68 | 2021 |
A new strategy to target acute myeloid leukemia stem and progenitor cells using chidamide, a histone deacetylase inhibitor Y Li, K Chen, Y Zhou, Y Xiao, M Deng, Z Jiang, W Ye, X Wang, X Wei, J Li, ... Current cancer drug targets 15 (6), 493-503, 2015 | 66 | 2015 |
Quantitative evaluation of the immunodeficiency of a mouse strain by tumor engraftments W Ye, Z Jiang, GX Li, Y Xiao, S Lin, Y Lai, S Wang, B Li, B Jia, Y Li, ... Journal of hematology & oncology 8, 1-13, 2015 | 48 | 2015 |
S100A10 is a critical mediator of GAs6/AXL–induced angiogenesis in renal cell carcinoma Y Xiao, H Zhao, L Tian, R Nolley, AN Diep, A Ernst, KC Fuh, YR Miao, ... Cancer research 79 (22), 5758-5768, 2019 | 44 | 2019 |
Neutralization of PD-L2 is essential for overcoming immune checkpoint blockade resistance in ovarian cancer YR Miao, KN Thakkar, J Qian, MS Kariolis, W Huang, S Nandagopal, ... Clinical cancer research 27 (15), 4435-4448, 2021 | 43 | 2021 |
ANGPTL7 regulates the expansion and repopulation of human hematopoietic stem and progenitor cells Y Xiao, Z Jiang, Y Li, W Ye, B Jia, M Zhang, Y Xu, D Wu, L Lai, Y Chen, ... haematologica 100 (5), 585, 2015 | 40 | 2015 |
High expression of TACC3 in esophageal squamous cell carcinoma correlates with poor prognosis ZL Huang, ZR Lin, YR Xiao, X Cao, LC Zhu, MS Zeng, Q Zhong, ZS Wen Oncotarget 6 (9), 6850, 2015 | 33 | 2015 |
GZD824 suppresses the growth of human B cell precursor acute lymphoblastic leukemia cells by inhibiting the SRC kinase and PI3K/AKT pathways W Ye, Z Jiang, X Lu, X Ren, M Deng, S Lin, Y Xiao, S Lin, S Wang, B Li, ... Oncotarget 8 (50), 87002, 2017 | 27 | 2017 |
Loss of Angiopoietin-like 7 diminishes the regeneration capacity of hematopoietic stem and progenitor cells Y Xiao, X Wei, Z Jiang, X Wang, W Ye, X Liu, M Zhang, Y Xu, D Wu, L Lai, ... Journal of hematology & oncology 8, 1-5, 2015 | 21 | 2015 |
Eliminating hypoxic tumor cells improves response to PARP inhibitors in homologous recombination–deficient cancer models M Mehibel, Y Xu, CG Li, EJ Moon, KN Thakkar, AN Diep, RK Kim, ... The Journal of clinical investigation 131 (11), 2021 | 19 | 2021 |
Repulsive guidance molecule B inhibits metastasis and is associated with decreased mortality in non-small cell lung cancer J Li, L Ye, X Shi, J Chen, F Feng, Y Chen, Y Xiao, J Shen, P Li, WG Jiang, ... Oncotarget 7 (13), 15678, 2016 | 19 | 2016 |
Heterogeneity of CD34 and CD38 expression in acute B lymphoblastic leukemia cells is reversible and not hierarchically organized Z Jiang, M Deng, X Wei, W Ye, Y Xiao, S Lin, S Wang, B Li, X Liu, ... Journal of Hematology & Oncology 9, 1-5, 2016 | 16 | 2016 |
Mechanisms determining the fate of hematopoietic stem cells S Lin, R Zhao, Y Xiao, P Li Stem cell investigation 2, 2015 | 12 | 2015 |
CD215+ myeloid cells respond to interleukin 15 stimulation and promote tumor progression S Lin, G Huang, Y Xiao, W Sun, Y Jiang, Q Deng, M Peng, X Wei, W Ye, ... Frontiers in Immunology 8, 1713, 2017 | 8 | 2017 |
Neutralizing PD-L1 and PD-L2 Enhances the Efficacy of Immune Checkpoint Inhibitors in Ovarian Cancer YR Miao, KN Thakkar, J Qian, MS Kariolis, H Wei, S Nandagopal, T Yang, ... bioRxiv, 2020.01. 19.911941, 2020 | 2 | 2020 |
Modulating the tumor microenvironment to enhance efficacy of PARP inhibitors. M Mehibel, J Xu, A Diep, K Thakkar, CG Li, Y Xiao, E Rankin, A Giaccia Journal of Clinical Oncology 37 (15_suppl), e14715-e14715, 2019 | 2 | 2019 |
Using mouse models to study function of transcriptional factors in T cell development P Li, Y Xiao, Z Liu, P Liu Cell Regeneration 1, 1-13, 2012 | 2 | 2012 |