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Zhi Yang
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mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants
Z Wang, F Schmidt, Y Weisblum, F Muecksch, CO Barnes, S Finkin, ...
Nature 592 (7855), 616-622, 2021
14522021
Detection and characterization of the SARS-CoV-2 lineage B. 1.526 in New York
AP West Jr, JO Wertheim, JC Wang, TI Vasylyeva, JL Havens, ...
Nature communications 12 (1), 4886, 2021
1012021
Partially open HIV-1 envelope structures exhibit conformational changes relevant for coreceptor binding and fusion
H Wang, CO Barnes, Z Yang, MC Nussenzweig, PJ Bjorkman
Cell Host & Microbe 24 (4), 579-592. e4, 2018
982018
Construction, characterization, and immunization of nanoparticles that display a diverse array of influenza HA trimers
AA Cohen, Z Yang, P Gnanapragasam, S Ou, KM Dam, H Wang, ...
50*2020
Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody
Z Yang, H Wang, AZ Liu, HB Gristick, PJ Bjorkman
Nature structural & molecular biology 26 (12), 1167-1175, 2019
432019
Electron tomography visualization of HIV-1 fusion with target cells using fusion inhibitors to trap the pre-hairpin intermediate
MS Ladinsky, PNP Gnanapragasam, Z Yang, AP West, MS Kay, ...
Elife 9, e58411, 2020
412020
Nanoparticles presenting clusters of CD4 expose a universal vulnerability of HIV-1 by mimicking target cells
MAG Hoffmann, Y Bar-On, Z Yang, HB Gristick, PNP Gnanapragasam, ...
Proceedings of the National Academy of Sciences 117 (31), 18719-18728, 2020
262020
Sequential immunization of macaques elicits heterologous neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env
A Escolano, HB Gristick, R Gautam, AT DeLaitsch, ME Abernathy, Z Yang, ...
Science translational medicine 13 (621), eabk1533, 2021
242021
Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer
Z Yang, KMA Dam, MD Bridges, MAG Hoffmann, AT DeLaitsch, ...
Nature communications 13 (1), 732, 2022
192022
ESCRT recruitment to SARS-CoV-2 spike induces virus-like particles that improve mRNA vaccines
MAG Hoffmann, Z Yang, KE Huey-Tubman, AA Cohen, ...
Cell 186 (11), 2380-2391. e9, 2023
112023
CD4 binding site immunogens elicit heterologous anti–HIV-1 neutralizing antibodies in transgenic and wild-type animals
HB Gristick, H Hartweger, M Loewe, J van Schooten, V Ramos, ...
Science Immunology 8 (80), eade6364, 2023
82023
Antibody recognition of CD4-induced open HIV-1 Env trimers
Z Yang, KMA Dam, JM Gershoni, S Zolla-Pazner, PJ Bjorkman
Journal of virology 96 (24), e01082-22, 2022
62022
Intermediate conformations of CD4-bound HIV-1 Env heterotrimers
KMA Dam, C Fan, Z Yang, PJ Bjorkman
Nature 623 (7989), 1017-1025, 2023
42023
mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants. Nature 10
Z Wang, F Schmidt, Y Weisblum, F Muecksch, CO Barnes, S Finkin, ...
4*2021
Structural characterization of HIV-1 Env heterotrimers bound to one or two CD4 receptors reveals intermediate Env conformations
KMA Dam, C Fan, Z Yang, PJ Bjorkman
bioRxiv, 2023
22023
ESCRT recruitment to mRNA-encoded SARS-CoV-2 spike induces virus-like particles and enhanced antibody responses
MAG Hoffmann, Z Yang, KE Huey-Tubman, AA Cohen, ...
BioRxiv, 2022
12022
Publisher Correction: Intermediate conformations of CD4-bound HIV-1 Env heterotrimers
KMA Dam, C Fan, Z Yang, PJ Bjorkman
Nature 626 (7998), E7, 2024
2024
ESCRT recruitment to mRNA-encoded SARS-CoV-2 spike induces virus-like particles and enhanced antibody responses (preprint)
MAG Hoffmann, Z Yang, KE Huey-Tubman, AA Cohen, ...
2022
Electron tomography visualization of HIV-1 inhibitors to trap the pre-hairpin intermediate 2
MS Ladinsky, PNP Gnanapragasam, Z Yang, AP West Jr, S Michael, ...
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