C-BERST: defining subnuclear proteomic landscapes at genomic elements with dCas9–APEX2 XD Gao, LC Tu, A Mir, T Rodriguez, Y Ding, J Leszyk, J Dekker, ... Nature methods 15 (6), 433-436, 2018 | 119 | 2018 |
An engineered ScCas9 with broad PAM range and high specificity and activity P Chatterjee, N Jakimo, J Lee, N Amrani, T Rodríguez, SRT Koseki, ... Nature Biotechnology 38 (10), 1154-1158, 2020 | 114 | 2020 |
A split prime editor with untethered reverse transcriptase and circular RNA template B Liu, X Dong, H Cheng, C Zheng, Z Chen, TC Rodríguez, SQ Liang, ... Nature Biotechnology 40 (9), 1388-1393, 2022 | 93 | 2022 |
Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo R Ibraheim, PWL Tai, A Mir, N Javeed, J Wang, TC Rodríguez, ... Nature communications 12 (1), 6267, 2021 | 63 | 2021 |
CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease E Tsagkaraki, SM Nicoloro, T DeSouza, J Solivan-Rivera, A Desai, ... Nature Communications 12 (1), 6931, 2021 | 44 | 2021 |
CRISPR/Cas9-mediated excision of ALS/FTD-causing hexanucleotide repeat expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro KE Meijboom, A Abdallah, NP Fordham, H Nagase, T Rodriguez, C Kraus, ... Nature communications 13 (1), 6286, 2022 | 35 | 2022 |
Adenine Base Editing In Vivo with a Single Adeno-Associated Virus Vector H Zhang, N Bamidele, P Liu, O Ojelabi, XD Gao, T Rodriguez, H Cheng, ... GEN biotechnology 1 (3), 285-299, 2022 | 30 | 2022 |
Pathogen infection and cholesterol deficiency activate the C. elegans p38 immune pathway through a TIR-1/SARM1 phase transition ND Peterson, JD Icso, JE Salisbury, T Rodríguez, PR Thompson, ... Elife 11, e74206, 2022 | 30 | 2022 |
Intratracheally administered LNA gapmer antisense oligonucleotides induce robust gene silencing in mouse lung fibroblasts M Shin, IL Chan, Y Cao, AM Gruntman, J Lee, J Sousa, TC Rodríguez, ... Nucleic Acids Research 50 (15), 8418-8430, 2022 | 15 | 2022 |
Androgen activity is associated with PD-L1 downregulation in thyroid cancer TJ O’Connell, S Dadafarin, M Jones, T Rodríguez, A Gupta, E Shin, ... Frontiers in Cell and Developmental Biology 9, 663130, 2021 | 14 | 2021 |
Genome-wide detection and analysis of CRISPR-Cas off-targets TC Rodríguez, S Dadafarin, HE Pratt, PP Liu, N Amrani, LJ Zhu Progress in molecular biology and translational science 181, 31-43, 2021 | 14 | 2021 |
YAP1 withdrawal in hepatoblastoma drives therapeutic differentiation of tumor cells to functional hepatocyte‐like cells JL Smith, TC Rodríguez, H Mou, SY Kwan, H Pratt, XO Zhang, Y Cao, ... Hepatology 73 (3), 1011-1027, 2021 | 13 | 2021 |
PAM-flexible genome editing with an engineered chimeric Cas9 L Zhao, SRT Koseki, RA Silverstein, N Amrani, C Peng, C Kramme, ... Nature Communications 14 (1), 6175, 2023 | 7 | 2023 |
Adapting dCas9-APEX2 for subnuclear proteomic profiling XD Gao, TC Rodríguez, EJ Sontheimer Methods in enzymology 616, 365-383, 2019 | 7 | 2019 |
MEG3 Expression Indicates Lymph Node Metastasis and Presence of Cancer-Associated Fibroblasts in Papillary Thyroid Cancer S Dadafarin, TC Rodríguez, MA Carnazza, RK Tiwari, A Moscatello, ... Cells 11 (19), 3181, 2022 | 5 | 2022 |
Dorsal column stimulation and cannabinoids in the treatment of chronic nociceptive and neuropathic pain: a review of the clinical and pre-clinical data CA Odonkor, T AlFarra, P Adekoya, V Orhurhu, T Rodríguez, E Sottosanti, ... Current pain and headache reports 26 (2), 103-118, 2022 | 4 | 2022 |
Precision Cas9 Genome Editing in vivo with All-in-one, Self-targeting AAV Vectors R Ibraheim, PWL Tai, A Mir, N Javeed, J Wang, T Rodríguez, S Nelson, ... bioRxiv, 2020.10. 09.333997, 2020 | 2 | 2020 |
PAM-Flexible genome editing with an engineered chimeric Cas9 S Koseki, L Hong, V Yudistyra, T Stan, E Tysinger, R Silverstein, ... Research Square, 2023 | 1 | 2023 |
Multiomics characterization of mouse hepatoblastoma identifies yes-associated protein 1 target genes. TC Rodríguez, SY Kwan, JL Smith, S Dadafarin, CH Wu, EJ Sontheimer, ... Hepatology (Baltimore, Md.) 78 (1), 58-71, 2022 | 1 | 2022 |
Sterol scarcity primes p38 immune defenses through a TIR-1/SARM1 phase transition ND Peterson, JD Icso, JE Salisbury, T Rodríguez, PR Thompson, ... bioRxiv, 2021.08. 05.455128, 2021 | 1 | 2021 |