Structural mechanism of cytosolic DNA sensing by cGAS F Civril, T Deimling, CC de Oliveira Mann, A Ablasser, M Moldt, G Witte, ... Nature 498 (7454), 332-337, 2013 | 752 | 2013 |
cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein–DNA ladders L Andreeva, B Hiller, D Kostrewa, C Lässig, CC de Oliveira Mann, ... Nature 549 (7672), 394-398, 2017 | 396 | 2017 |
Bacterial cGAS-like enzymes synthesize diverse nucleotide signals AT Whiteley, JB Eaglesham, CC de Oliveira Mann, BR Morehouse, ... Nature 567 (7747), 194-199, 2019 | 301 | 2019 |
Structure of the human cGAS–DNA complex reveals enhanced control of immune surveillance W Zhou, AT Whiteley, CC de Oliveira Mann, BR Morehouse, RP Nowak, ... Cell 174 (2), 300-311. e11, 2018 | 279 | 2018 |
Structural basis for sequestration and autoinhibition of cGAS by chromatin S Michalski, CC de Oliveira Mann, CA Stafford, G Witte, J Bartho, ... Nature 587 (7835), 678-682, 2020 | 180 | 2020 |
Modular architecture of the STING C-terminal tail allows interferon and NF-κB signaling adaptation CC de Oliveira Mann, MH Orzalli, DS King, JC Kagan, ASY Lee, ... Cell reports 27 (4), 1165-1175. e5, 2019 | 161 | 2019 |
ATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA C Lässig, S Matheisl, KMJ Sparrer, CC de Oliveira Mann, M Moldt, ... Elife 4, e10859, 2015 | 105 | 2015 |
Hedycaryol synthase in complex with nerolidol reveals terpene cyclase mechanism P Baer, P Rabe, CA Citron, CC de Oliveira Mann, N Kaufmann, M Groll, ... ChemBioChem 15 (2), 213-216, 2014 | 76 | 2014 |
cGAS conducts micronuclei DNA surveillance CC de Oliveira Mann, PJ Kranzusch Trends in cell biology 27 (10), 697-698, 2017 | 56 | 2017 |
Structural and biochemical characterization of the cell fate determining nucleotidyltransferase fold protein MAB21L1 CC de Oliveira Mann, R Kiefersauer, G Witte, KP Hopfner Scientific reports 6 (1), 27498, 2016 | 45 | 2016 |
Nuclear cGAS: guard or prisoner? CC de Oliveira Mann, KP Hopfner The EMBO Journal 40 (16), e108293, 2021 | 40 | 2021 |
Impact of heterogeneity and lattice bond strength on DNA triangle crystal growth E Stahl, F Praetorius, CC de Oliveira Mann, KP Hopfner, H Dietz ACS nano 10 (10), 9156-9164, 2016 | 36 | 2016 |
Molecular mechanisms of nonself nucleic acid recognition by the innate immune system CC de Oliveira Mann, V Hornung European journal of immunology 51 (8), 1897-1910, 2021 | 34 | 2021 |
cGLRs are a diverse family of pattern recognition receptors in innate immunity Y Li, KM Slavik, HC Toyoda, BR Morehouse, CC de Oliveira Mann, A Elek, ... Cell 186 (15), 3261-3276. e20, 2023 | 26 | 2023 |
Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation CA Stafford, AM Gassauer, CC de Oliveira Mann, MC Tanzer, E Fessler, ... Nature 609 (7927), 590-596, 2022 | 22 | 2022 |
OAS1/RNase L executes RIG-I ligand–dependent tumor cell apoptosis DFR Boehmer, S Formisano, CC de Oliveira Mann, SA Mueller, M Kluge, ... Science Immunology 6 (61), eabe2550, 2021 | 22 | 2021 |
Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing N Kessler, SF Viehmann, C Krollmann, K Mai, KM Kirschner, H Luksch, ... Journal of Experimental Medicine 219 (10), e20220759, 2022 | 12 | 2022 |
ARF1 prevents aberrant type I interferon induction by regulating STING activation and recycling M Hirschenberger, A Lepelley, U Rupp, S Klute, V Hunszinger, L Koepke, ... Nature Communications 14 (1), 6770, 2023 | 6 | 2023 |
UNC93B1 variants underlie TLR7-dependent autoimmunity C Wolf, EL Lim, M Mokhtari, B Kind, A Odainic, E Lara-Villacanas, S Koss, ... Science immunology, eadi9769, 2024 | 5 | 2024 |
cGLRs are a diverse family of pattern recognition receptors in animal innate immunity Y Li, KM Slavik, BR Morehouse, CC de Oliveira Mann, K Mears, J Liu, ... bioRxiv, 2023 | 3 | 2023 |