| A mild and efficient route to Schiff base derivatives of amino acids MJ O'Donnell, RL Polt The Journal of Organic Chemistry 47 (13), 2663-2666, 1982 | 497 | 1982 |
| Glycopeptide enkephalin analogues produce analgesia in mice: evidence for penetration of the blood-brain barrier. R Polt, F Porreca, LZ Szabo, EJ Bilsky, P Davis, TJ Abbruscato, TP Davis, ... Proceedings of the National Academy of Sciences 91 (15), 7114-7118, 1994 | 304 | 1994 |
| Acidities of glycine Schiff bases and alkylation of their conjugate bases MJ O'Donnell, WD Bennett, WA Bruder, WN Jacobsen, K Knuth, B LeClef, ... Journal of the American Chemical Society 110 (25), 8520-8525, 1988 | 202 | 1988 |
| Solid-phase synthesis of O-linked glycopeptide analogues of enkephalin SA Mitchell, MR Pratt, VJ Hruby, R Polt The Journal of Organic Chemistry 66 (7), 2327-2342, 2001 | 177 | 2001 |
| General methods for. alpha.-or. beta.-O-Ser/Thr glycosides and glycopeptides. Solid-phase synthesis of O-glycosyl cyclic enkephalin analogs R Polt, L Szabo, J Treiberg, Y Li, VJ Hruby Journal of the American Chemical Society 114 (26), 10249-10258, 1992 | 162 | 1992 |
| Enkephalin glycopeptide analogues produce analgesia with reduced dependence liability EJ Bilsky, RD Egleton, SA Mitchell, MM Palian, P Davis, JD Huber, ... Journal of medicinal chemistry 43 (13), 2586-2590, 2000 | 147 | 2000 |
| Improved bioavailability to the brain of glycosylated Met-enkephalin analogs RD Egleton, SA Mitchell, JD Huber, J Janders, D Stropova, R Polt, ... Brain research 881 (1), 37-46, 2000 | 143 | 2000 |
| Aluminoxy acetals from. alpha.-amino esters: chirality transfer via sequential addition of hydride and C-nucleophiles. 2-Amino alcohols and sphingosines R Polt, MA Peterson, L DeYoung The Journal of Organic Chemistry 57 (20), 5469-5480, 1992 | 140 | 1992 |
| A systematic study of glycolaldehyde in Sagittarius B2 (N) at 2 and 3 mm: Criteria for detecting large interstellar molecules DT Halfen, AJ Apponi, N Woolf, R Polt, LM Ziurys The Astrophysical Journal 639 (1), 237, 2006 | 137 | 2006 |
| Improved blood-brain barrier penetration and enhanced analgesia of an opioid peptide by glycosylation RD Egleton, SA Mitchell, JD Huber, MM Palian, R Polt, TP Davis Journal of Pharmacology and Experimental Therapeutics 299 (3), 967-972, 2001 | 127 | 2001 |
| Assessment of an in vitro blood-brain barrier model using several [Met5] enkephalin opioid analogs. SJ Weber, TJ Abbruscato, EA Brownson, AW Lipkowski, R Polt, A Misicka, ... Journal of Pharmacology and Experimental Therapeutics 266 (3), 1649-1655, 1993 | 105 | 1993 |
| In vivo characterization of MMP-2200, a mixed δ/μ opioid agonist, in mice JJ Lowery, TJ Raymond, D Giuvelis, JM Bidlack, R Polt, EJ Bilsky Journal of pharmacology and experimental therapeutics 336 (3), 767-778, 2011 | 91 | 2011 |
| Glycosylated neuropeptides: a new vista for neuropsychopharmacology? R Polt, M Dhanasekaran, CM Keyari Medicinal research reviews 25 (5), 557-585, 2005 | 91 | 2005 |
| Antinociceptive structure-activity studies with enkephalin-based opioid glycopeptides NO Elmagbari, RD Egleton, MM Palian, JJ Lowery, WR Schmid, P Davis, ... Journal of Pharmacology and Experimental Therapeutics 311 (1), 290-297, 2004 | 74 | 2004 |
| Stereoselective alkylation of glycine units in dipeptide derivatives." Chirality transfer" via a pivalaldehyde N, N-acetal center R Polt, D Seebach Journal of the American Chemical Society 111 (7), 2622-2632, 1989 | 72 | 1989 |
| Catalysis by amino acid-derived tetracoordinate complexes: enantioselective addition of dialkylzincs to aliphatic and aromatic aldehydes BD Dangel, R Polt Organic Letters 2 (19), 3003-3006, 2000 | 67 | 2000 |
| Amino acid-derived ligands for transition metals: Catalysis via a minimalist interpretation of a metalloprotein B Dangel, M Clarke, J Haley, D Sames, R Polt Journal of the American Chemical Society 119 (44), 10865-10866, 1997 | 67 | 1997 |
| Glycopeptide-membrane interactions: glycosyl enkephalin analogues adopt turn conformations by NMR and CD in amphipathic media MM Palian, VI Boguslavsky, DF O'Brie, R Polt Journal of the American Chemical Society 125 (19), 5823-5831, 2003 | 66 | 2003 |
| Opioid glycopeptide analgesics derived from endogenous enkephalins and endorphins Y Li, MR Lefever, D Muthu, JM Bidlack, EJ Bilsky, R Polt Future medicinal chemistry 4 (2), 205-226, 2012 | 62 | 2012 |
| Asymmetric Syntheses of (−)-8-epi-Swainsonine Triacetate and (+)-1,2-Di-epi-swainsonine. Carbonyl Addition Thwarted by an Unprecedented Aza-Pinacol … H Razavi, R Polt The Journal of Organic Chemistry 65 (18), 5693-5706, 2000 | 62 | 2000 |
Edward BilskyPacific Northwest UniversityVerified email at pnwu.edu
