A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing Y Zhao, G Lang, S Ito, J Bonnet, E Metzger, S Sawatsubashi, E Suzuki, ... Molecular cell 29 (1), 92-101, 2008 | 417 | 2008 |
MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties X Le Guezennec, M Vermeulen, AB Brinkman, WAM Hoeijmakers, ... Molecular and cellular biology 26 (3), 843-851, 2006 | 398 | 2006 |
WIP1 phosphatase at the crossroads of cancer and aging X Le Guezennec, DV Bulavin Trends in biochemical sciences 35 (2), 109-114, 2010 | 155 | 2010 |
Wip1-dependent regulation of autophagy, obesity, and atherosclerosis X Le Guezennec, A Brichkina, YF Huang, E Kostromina, W Han, ... Cell metabolism 16 (1), 68-80, 2012 | 151 | 2012 |
p38MAPK controls expression of multiple cell cycle inhibitors and islet proliferation with advancing age ESM Wong, X Le Guezennec, ON Demidov, NT Marshall, ST Wang, ... Developmental cell 17 (1), 142-149, 2009 | 117 | 2009 |
The human SPT20-containing SAGA complex plays a direct role in the regulation of endoplasmic reticulum stress-induced genes Z Nagy, A Riss, C Romier, X Le Guezennec, AR Dongre, M Orpinell, ... Molecular and cellular biology 29 (6), 1649-1660, 2009 | 82 | 2009 |
Wip1 promotes RUNX2-dependent apoptosis in p53-negative tumors and protects normal tissues during treatment with anticancer agents AR Goloudina, K Tanoue, A Hammann, E Fourmaux, X Le Guezennec, ... Proceedings of the National Academy of Sciences 109 (2), E68-E75, 2012 | 53 | 2012 |
Molecular characterization of Sin3 PAH-domain interactor specificity and identification of PAH partners X Le Guezennec, M Vermeulen, HG Stunnenberg Nucleic acids research 34 (14), 3929-3937, 2006 | 53 | 2006 |
A feed-forward repression mechanism anchors the Sin3/histone deacetylase and N-CoR/SMRT corepressors on chromatin M Vermeulen, W Walter, X Le Guezennec, J Kim, RS Edayathumangalam, ... Molecular and cellular biology 26 (14), 5226-5236, 2006 | 34 | 2006 |
Myeloid transforming protein Evi1 interacts with methyl-CpG binding domain protein 3 and inhibits in vitro histone deacetylation by Mbd3/Mi-2/NuRD D Spensberger, M Vermeulen, X Le Guezennec, R Beekman, ... Biochemistry 47 (24), 6418-6426, 2008 | 27 | 2008 |
Transferring Luminex® cytokine assays to a wall-less plate technology: Validation and comparison study with plasma and cell culture supernatants L Versteeg, X Le Guezennec, B Zhan, Z Liu, M Angagaw, JD Woodhouse, ... Journal of immunological methods 440, 74-82, 2017 | 26 | 2017 |
ER-resident oxidoreductases are glycosylated and trafficked to the cell surface to promote matrix degradation by tumour cells M Ros, AT Nguyen, J Chia, S Le Tran, X Le Guezennec, R McDowall, ... Nature cell biology 22 (11), 1371-1381, 2020 | 25 | 2020 |
Human tear analysis with miniaturized multiplex cytokine assay on “wall-less” 96-well plate X Le Guezennec, J Quah, L Tong, N Kim Molecular Vision 21, 1151, 2015 | 24 | 2015 |
Molecular determinants of the interaction of Mad with the PAH2 domain of mSin3 X Le Guezennec, G Vriend, HG Stunnenberg Journal of Biological Chemistry 279 (24), 25823-25829, 2004 | 13 | 2004 |
Targeted discovery tools: proteomics and chromatin immunoprecipitation‐on‐chip X Le Guezennec, AB Brinkman, M Vermeulen, SÏG Denissov, C Gazziola, ... BJU international 96, 16-22, 2005 | 9 | 2005 |
Digging deep into Golgi phenotypic diversity with unsupervised machine learning S Hussain, X Le Guezennec, W Yi, H Dong, J Chia, K Yiping, LK Khoon, ... Molecular Biology of the Cell 28 (25), 3686-3698, 2017 | 8 | 2017 |
Miniaturization of mitotic index cell-based assay using “wall-less” plate technology X Le Guezennec, M Phong, L Nor, N Kim ASSAY and Drug Development Technologies 12 (2), 129-135, 2014 | 4 | 2014 |
Internalisation of integrin-bound extracellular matrix modulates invasive carcinoma cell migration M Llanses Martinez, K Nan, Z Bao, R Bacchetti, S Yuan, J Tyler, ... bioRxiv, 2024.01. 11.575153, 2024 | 1 | 2024 |
Improving Bead-Based Multiplexing in Bodily Fluids: Novel System Enhances Bead-Based Multiplexing Assays Using Less Sample and Reagent While Achieving Optimal Cytokine Sensitivity X Le Guezennec, M Lye Genetic Engineering & Biotechnology News 36 (2), 12-13, 2016 | 1 | 2016 |
Internalisation of integrin-bound extracellular matrix modulates invasive carcinoma cell migration K Nan, Z Bao, R Bacchetti, S Yuan, J Tyler, X Le Guezennec, FA Bard, ... | | 2024 |