| The revolution continues: newly discovered systems expand the CRISPR-Cas toolkit K Murugan, K Babu, R Sundaresan, R Rajan, DG Sashital Molecular cell 68 (1), 15-25, 2017 | 207 | 2017 |
| CRISPR-Cas12a has widespread off-target and dsDNA-nicking effects K Murugan, AS Seetharam, AJ Severin, DG Sashital Journal of Biological Chemistry 295 (17), 5538-5553, 2020 | 103 | 2020 |
| High-frequency random DNA insertions upon co-delivery of CRISPR-Cas9 ribonucleoprotein and selectable marker plasmid in rice R Banakar, AL Eggenberger, K Lee, DA Wright, K Murugan, S Zarecor, ... Scientific Reports 9 (19902), 2019 | 78 | 2019 |
| Systematic in vitro specificity profiling reveals nicking defects in natural and engineered CRISPR–Cas9 variants K Murugan, SK Suresh, AS Seetharam, AJ Severin, DG Sashital Nucleic Acids Research 49 (7), 4037-4053, 2021 | 13 | 2021 |
| Comparative analysis of CRISPR off-target discovery tools following ex vivo editing of CD34+ hematopoietic stem and progenitor cells MK Cromer, KR Majeti, GR Rettig, K Murugan, GL Kurgan, NM Bode, ... Molecular Therapy 31 (4), 1074-1087, 2023 | 6 | 2023 |
| Enzymatic anti-CRISPRs improve the bacteriophage arsenal SK Suresh, K Murugan, DG Sashital Nature structural & molecular biology 26 (4), 250-251, 2019 | 6 | 2019 |
| CRISPR–Cas molecular beacons as tool for studies of assembly of CRISPR–Cas effector complexes and their interactions with DNA V Mekler, K Kuznedelov, L Minakhin, K Murugan, DG Sashital, ... Methods in enzymology 616, 337-363, 2019 | 6 | 2019 |
| Pervasive off-target and double-stranded DNA nicking by CRISPR-Cas12a K Murugan, AS Seetharam, AJ Severin, DG Sashital BioRxiv, 657791, 2019 | 4 | 2019 |
| Comparative analysis of CRISPR off-target activity discovery tools following ex vivo editing of CD34+ hematopoietic stem and progenitor cells MK Cromer, KR Majeti, GR Rettig, K Murugan, GL Kurgan, JP Hampton, ... BioRxiv, 2022.09. 09.507306, 2022 | 3 | 2022 |
| High-throughput in vitro specificity profiling of natural and high-fidelity CRISPR-Cas9 variants K Murugan, AS Seetharam, AJ Severin, DG Sashital bioRxiv, 2020.05. 12.091991, 2020 | 1 | 2020 |
| Characterizing the specificity and nicking activity of CRISPR endonucleases, Cas9 and Cas12a K Murugan Iowa State University, 2020 | 1 | 2020 |
| Improved methods for large hdr knock-ins using ALT-R (TM) HDR donor blocks and ALT-R HDR enhancer V2 J Woodley, B Thommandru, R Nath, A Brunet, L Krueger, A Morris, ... TRANSGENIC RESEARCH 31 (SUPPL 1), 15-15, 2022 | | 2022 |
| Improved Methods for Large HDR Knock-Ins Using Alt-RT HDR Donor Blocks and Alt-R (TM) HDR Enhancer V2 J Woodley, R Turk, B Thommandru, M Schubert, K Murugan, G Kurgan, ... MOLECULAR THERAPY 30 (4), 94-94, 2022 | | 2022 |
| Differential nicking patterns of Cas12a variants K Murugan, DG Sashital The FASEB Journal 33 (S1), 620.7-620.7, 2019 | | 2019 |
| Duplex DNA Destabilization by Type V CRISPR-Cas Nucleases during Interrogation of DNA V Mekler, L Minakhin, K Kuznedelov, K Murugan, D Sashital, K Severinov Biophysical Journal 114 (3), 250a, 2018 | | 2018 |
Dipali SashitalIowa State UniversityVerified email at iastate.edu
