Whole-genome sequencing for prediction of Mycobacterium tuberculosis drug susceptibility and resistance: a retrospective cohort study TM Walker, TA Kohl, SV Omar, J Hedge, CDO Elias, P Bradley, Z Iqbal, ... The Lancet infectious diseases 15 (10), 1193-1202, 2015 | 616 | 2015 |
Rapid antibiotic-resistance predictions from genome sequence data for Staphylococcus aureus and Mycobacterium tuberculosis P Bradley, NC Gordon, TM Walker, L Dunn, S Heys, B Huang, S Earle, ... Nature communications 6 (1), 10063, 2015 | 598 | 2015 |
Transmission of extensively drug-resistant tuberculosis in South Africa NS Shah, SC Auld, JCM Brust, B Mathema, N Ismail, P Moodley, ... New England Journal of Medicine 376 (3), 243-253, 2017 | 339 | 2017 |
Prediction of susceptibility to first-line tuberculosis drugs by DNA sequencing CRyPTIC Consortium and the 100,000 Genomes Project New England Journal of Medicine 379 (15), 1403-1415, 2018 | 320 | 2018 |
Population-based resistance of Mycobacterium tuberculosis isolates to pyrazinamide and fluoroquinolones: results from a multicountry surveillance project M Zignol, AS Dean, N Alikhanova, S Andres, AM Cabibbe, DM Cirillo, ... The Lancet infectious diseases 16 (10), 1185-1192, 2016 | 206 | 2016 |
Genetic sequencing for surveillance of drug resistance in tuberculosis in highly endemic countries: a multi-country population-based surveillance study M Zignol, AM Cabibbe, AS Dean, P Glaziou, N Alikhanova, C Ama, ... The Lancet Infectious Diseases 18 (6), 675-683, 2018 | 157 | 2018 |
The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: a genotypic analysis TM Walker, P Miotto, CU Köser, PW Fowler, J Knaggs, Z Iqbal, M Hunt, ... The Lancet Microbe 3 (4), e265-e273, 2022 | 138 | 2022 |
Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe M Hunt, P Bradley, SG Lapierre, S Heys, M Thomsit, MB Hall, KM Malone, ... Wellcome open research 4, 2019 | 118 | 2019 |
Next-generation ion torrent sequencing of drug resistance mutations in Mycobacterium tuberculosis strains LT Daum, JD Rodriguez, SA Worthy, NA Ismail, SV Omar, AW Dreyer, ... Journal of clinical microbiology 50 (12), 3831-3837, 2012 | 112 | 2012 |
Modernizing Medical Microbiology (MMM) Informatics Group. Whole-genome sequencing for prediction of Mycobacterium tuberculosis drug susceptibility and resistance: a … TM Walker, TA Kohl, SV Omar, J Hedge, C Del Ojo Elias, P Bradley, ... Lancet Infect Dis 15 (10), 1193-1202, 2015 | 109 | 2015 |
Defining bedaquiline susceptibility, resistance, cross-resistance and associated genetic determinants: a retrospective cohort study NA Ismail, SV Omar, L Joseph, N Govender, L Blows, F Ismail, H Koornhof, ... EBioMedicine 28, 136-142, 2018 | 106 | 2018 |
Prevalence of drug-resistant tuberculosis and imputed burden in South Africa: a national and sub-national cross-sectional survey NA Ismail, L Mvusi, A Nanoo, A Dreyer, SV Omar, S Babatunde, ... The Lancet Infectious Diseases 18 (7), 779-787, 2018 | 91 | 2018 |
Molecular identification and genotyping of MRSA isolates PE Makgotlho, MM Kock, A Hoosen, R Lekalakala, S Omar, M Dove, ... FEMS Immunology & Medical Microbiology 57 (2), 104-115, 2009 | 88 | 2009 |
Evaluation of the GenoType MTBDRsl Version 2.0 Assay for Second-Line Drug Resistance Detection of Mycobacterium tuberculosis Isolates in South Africa Y Gardee, AW Dreyer, HJ Koornhof, SV Omar, P Da Silva, Z Bhyat, ... Journal of clinical microbiology 55 (3), 791-800, 2017 | 82 | 2017 |
Multicenter Noninferiority Evaluation of Hain GenoType MTBDRplus Version 2 and Nipro NTM+MDRTB Line Probe Assays for Detection of Rifampin and Isoniazid … RR Nathavitharana, D Hillemann, SG Schumacher, B Schlueter, N Ismail, ... Journal of clinical microbiology 54 (6), 1624-1630, 2016 | 75 | 2016 |
Assessment of epidemiological and genetic characteristics and clinical outcomes of resistance to bedaquiline in patients treated for rifampicin-resistant tuberculosis: a cross … NA Ismail, SV Omar, H Moultrie, Z Bhyat, F Conradie, M Enwerem, ... The Lancet Infectious Diseases 22 (4), 496-506, 2022 | 61 | 2022 |
MDR M. tuberculosis outbreak clone in Eswatini missed by Xpert has elevated bedaquiline resistance dated to the pre-treatment era P Beckert, E Sanchez-Padilla, M Merker, V Dreyer, TA Kohl, C Utpatel, ... Genome Medicine 12, 1-11, 2020 | 60 | 2020 |
A data compendium associating the genomes of 12,289 Mycobacterium tuberculosis isolates with quantitative resistance phenotypes to 13 antibiotics CRyPTIC Consortium PLoS biology 20 (8), e3001721, 2022 | 48 | 2022 |
Evaluation of the GenoType® MTBDRsl assay for susceptibility testing of second-line anti-tuberculosis drugs HM Said, MM Kock, NA Ismail, K Baba, SV Omar, AG Osman, AA Hoosen, ... The International journal of tuberculosis and lung disease 16 (1), 104-109, 2012 | 47 | 2012 |
In Vitro Study of Stepwise Acquisition of rv0678 and atpE Mutations Conferring Bedaquiline Resistance N Ismail, NA Ismail, SV Omar, RPH Peters Antimicrobial agents and chemotherapy 63 (8), 10.1128/aac. 00292-19, 2019 | 43 | 2019 |