| Biology and applications of CRISPR systems: harnessing nature’s toolbox for genome engineering AV Wright, JK Nuñez, JA Doudna Cell 164 (1), 29-44, 2016 | 1161 | 2016 |
| A multiplexed single-cell CRISPR screening platform enables systematic dissection of the unfolded protein response B Adamson, TM Norman, M Jost, MY Cho, JK Nuñez, Y Chen, JE Villalta, ... Cell 167 (7), 1867-1882. e21, 2016 | 973 | 2016 |
| Cas1–Cas2 complex formation mediates spacer acquisition during CRISPR–Cas adaptive immunity JK Nuñez, PJ Kranzusch, J Noeske, AV Wright, CW Davies, JA Doudna Nature structural & molecular biology 21 (6), 528-534, 2014 | 560 | 2014 |
| Pervasive functional translation of noncanonical human open reading frames J Chen, AD Brunner, JZ Cogan, JK Nuñez, AP Fields, B Adamson, ... Science 367 (6482), 1140-1146, 2020 | 451 | 2020 |
| Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity JK Nuñez, ASY Lee, A Engelman, JA Doudna Nature 519 (7542), 193-198, 2015 | 416 | 2015 |
| Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing JK Nuñez, J Chen, GC Pommier, JZ Cogan, JM Replogle, C Adriaens, ... Cell 184 (9), 2503-2519. e17, 2021 | 363 | 2021 |
| Foreign DNA capture during CRISPR–Cas adaptive immunity JK Nuñez, LB Harrington, PJ Kranzusch, AN Engelman, JA Doudna Nature 527 (7579), 535-538, 2015 | 230 | 2015 |
| Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1 CA Musselman, N Avvakumov, R Watanabe, CG Abraham, ME Lalonde, ... Nature structural & molecular biology 19 (12), 1266-1272, 2012 | 228 | 2012 |
| Inducible and multiplex gene regulation using CRISPR–Cpf1-based transcription factors YE Tak, BP Kleinstiver, JK Nuñez, JY Hsu, JE Horng, J Gong, ... Nature methods 14 (12), 1163-1166, 2017 | 204 | 2017 |
| CRISPR immunological memory requires a host factor for specificity JK Nuñez, L Bai, LB Harrington, TL Hinder, JA Doudna Molecular cell 62 (6), 824-833, 2016 | 191 | 2016 |
| Chemical and biophysical modulation of Cas9 for tunable genome engineering JK Nuñez, LB Harrington, JA Doudna ACS chemical biology 11 (3), 681-688, 2016 | 119 | 2016 |
| BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2 AJ Samelson, QD Tran, R Robinot, L Carrau, VV Rezelj, AM Kain, M Chen, ... Nature cell biology 24 (1), 24-34, 2022 | 64* | 2022 |
| Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq S Sunshine, AS Puschnik, JM Replogle, MT Laurie, J Liu, BS Zha, ... Nature Communications 14 (1), 6245, 2023 | 8 | 2023 |
| CRISPR meets caspase ML Hochstrasser, JK Nuñez Nature Microbiology 6 (12), 1481-1482, 2021 | 4 | 2021 |
| Methods and compositions for nucleic acid integration JK Nunez, JA Doudna US Patent 11,053,271, 2021 | 3 | 2021 |
| Compositions and methods for gene editing J Chen, L Gilbert, J Nunez, J Weissman US Patent 11,434,491, 2022 | 1 | 2022 |
| Neural space-time model for dynamic scene recovery in multi-shot computational imaging systems R Cao, N Divekar, J Nuñez, S Upadhyayula, L Waller bioRxiv, 2024.01. 16.575950, 2024 | | 2024 |
| Compositions and methods for epigenome editing L Gilbert, J Weissman, J Nunez, G Pommier US Patent App. 17/999,762, 2023 | | 2023 |
| Compositions and Methods for Gene Editing J Chen, L Gilbert, J Nunez, J Weissman US Patent App. 17/816,369, 2023 | | 2023 |
| Compositions and methods for gene editing J Chen, L Gilbert, J Nunez, J Weissman US Patent App. 17/726,290, 2023 | | 2023 |
