| Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets JM Balko, JM Giltnane, K Wang, LJ Schwarz, CD Young, RS Cook, ... Cancer discovery 4 (2), 232-245, 2014 | 542 | 2014 |
| Role of TGFβ-mediated inflammation in cutaneous wound healing XJ Wang, G Han, P Owens, Y Siddiqui, AG Li Journal of Investigative Dermatology Symposium Proceedings 11 (1), 112-117, 2006 | 283 | 2006 |
| Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-β–deficient mouse mammary carcinomas MW Pickup, H Laklai, I Acerbi, P Owens, AE Gorska, A Chytil, M Aakre, ... Cancer research 73 (17), 5336-5346, 2013 | 207 | 2013 |
| Smad7-induced β-catenin degradation alters epidermal appendage development G Han, AG Li, YY Liang, P Owens, W He, S Lu, Y Yoshimatsu, D Wang, ... Developmental cell 11 (3), 301-312, 2006 | 182 | 2006 |
| IKKα is a critical coregulator of a Smad4-independent TGFβ-Smad2/3 signaling pathway that controls keratinocyte differentiation P Descargues, AK Sil, Y Sano, O Korchynskyi, G Han, P Owens, XJ Wang, ... Proceedings of the National Academy of Sciences 105 (7), 2487-2492, 2008 | 173 | 2008 |
| Activation of MAPK pathways due to DUSP4 loss promotes cancer stem cell-like phenotypes in basal-like breast cancer JM Balko, LJ Schwarz, NE Bhola, R Kurupi, P Owens, TW Miller, H Gómez, ... Cancer research 73 (20), 6346-6358, 2013 | 159 | 2013 |
| TGF-β receptor II loss promotes mammary carcinoma progression by Th17-dependent mechanisms SV Novitskiy, MW Pickup, AE Gorska, P Owens, A Chytil, M Aakre, H Wu, ... Cancer discovery 1 (5), 430-441, 2011 | 154 | 2011 |
| Efferocytosis produces a prometastatic landscape during postpartum mammary gland involution JC Stanford, C Young, D Hicks, P Owens, A Williams, DB Vaught, ... The Journal of clinical investigation 124 (11), 4737-4752, 2014 | 135 | 2014 |
| Fibroblast-mediated collagen remodeling within the tumor microenvironment facilitates progression of thyroid cancers driven by BrafV600E and Pten loss LA Jolly, S Novitskiy, P Owens, N Massoll, N Cheng, W Fang, HL Moses, ... Cancer research 76 (7), 1804-1813, 2016 | 123 | 2016 |
| Role of TGF-β signaling in generation of CD39+ CD73+ myeloid cells in tumors SV Ryzhov, MW Pickup, A Chytil, AE Gorska, Q Zhang, P Owens, ... The Journal of Immunology 193 (6), 3155-3164, 2014 | 121 | 2014 |
| Hair follicle defects and squamous cell carcinoma formation in Smad4 conditional knockout mouse skin W Qiao, AG Li, P Owens, X Xu, XJ Wang, CX Deng Oncogene 25 (2), 207-217, 2006 | 119 | 2006 |
| Inhibition of BMP signaling suppresses metastasis in mammary cancer P Owens, MW Pickup, SV Novitskiy, JM Giltnane, AE Gorska, CR Hopkins, ... Oncogene 34 (19), 2437-2449, 2015 | 114 | 2015 |
| PI3K inhibition reduces mammary tumor growth and facilitates antitumor immunity and anti-PD1 responses J Sai, P Owens, SV Novitskiy, OE Hawkins, AE Vilgelm, J Yang, T Sobolik, ... Clinical Cancer Research 23 (13), 3371-3384, 2017 | 98 | 2017 |
| Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators P Owens, MW Pickup, SV Novitskiy, A Chytil, AE Gorska, ME Aakre, ... Proceedings of the National Academy of Sciences 109 (8), 2814-2819, 2012 | 93 | 2012 |
| Deletion of TGF-β signaling in myeloid cells enhances their anti-tumorigenic properties SV Novitskiy, MW Pickup, A Chytil, D Polosukhina, P Owens, HL Moses Journal of leukocyte biology 92 (3), 641-651, 2012 | 88 | 2012 |
| HER2-overexpressing breast cancers amplify FGFR signaling upon acquisition of resistance to dual therapeutic blockade of HER2 AB Hanker, JT Garrett, MV Estrada, PD Moore, PG Ericsson, JP Koch, ... Clinical Cancer Research 23 (15), 4323-4334, 2017 | 81 | 2017 |
| The role of Smads in skin development P Owens, G Han, AG Li, XJ Wang Journal of Investigative Dermatology 128 (4), 783-790, 2008 | 79 | 2008 |
| The bone microenvironment: a fertile soil for tumor growth D Buenrostro, PL Mulcrone, P Owens, JA Sterling Current osteoporosis reports 14, 151-158, 2016 | 70 | 2016 |
| Therapeutically targeting tumor microenvironment–mediated drug resistance in estrogen receptor–positive breast cancer K Shee, W Yang, JW Hinds, RA Hampsch, FS Varn, NA Traphagen, ... Journal of Experimental Medicine 215 (3), 895-910, 2018 | 69 | 2018 |
| Overexpression of PIK3CA in murine head and neck epithelium drives tumor invasion and metastasis through PDK1 and enhanced TGFβ signaling L Du, X Chen, Y Cao, L Lu, F Zhang, S Bornstein, Y Li, P Owens, ... Oncogene 35 (35), 4641-4652, 2016 | 69 | 2016 |
Sergey V. NovitskiyResearch Associate Professor at VUMCVerified email at vumc.org
