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Martha Chekenya
Martha Chekenya
Verified email at uib.no
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Elevated CD3+ and CD8+ tumor-infiltrating immune cells correlate with prolonged survival in glioblastoma patients despite integrated immunosuppressive mechanisms in the tumor …
J Kmiecik, A Poli, NHC Brons, A Waha, GE Eide, PØ Enger, J Zimmer, ...
Journal of neuroimmunology 264 (1-2), 71-83, 2013
4052013
Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics
C Krakstad, M Chekenya
Molecular cancer 9, 1-14, 2010
3852010
Angiogenesis-independent tumor growth mediated by stem-like cancer cells
PØ Sakariassen, L Prestegarden, J Wang, KO Skaftnesmo, ...
Proceedings of the National Academy of Sciences 103 (44), 16466-16471, 2006
2622006
Therapeutic potential and challenges of natural killer cells in treatment of solid tumors
A Gras Navarro, AT Björklund, M Chekenya
Frontiers in immunology 6, 139254, 2015
2142015
Cancer stem cells as mediators of treatment resistance in brain tumors: status and controversies
PØ Sakariassen, H Immervoll, M Chekenya
Neoplasia 9 (11), 882-892, 2007
1952007
The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling
M Chekenya, C Krakstad, A Svendsen, IA Netland, V Staalesen, ...
Oncogene 27 (39), 5182-5194, 2008
1872008
U‐251 revisited: genetic drift and phenotypic consequences of long‐term cultures of glioblastoma cells
A Torsvik, D Stieber, PØ Enger, A Golebiewska, A Molven, A Svendsen, ...
Cancer medicine 3 (4), 812-824, 2014
1832014
Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma
A Svendsen, JJC Verhoeff, H Immervoll, JC Brøgger, J Kmiecik, A Poli, ...
Acta neuropathologica 122, 495-510, 2011
1522011
NG2 proteoglycan promotes angiogenesis‐dependent tumor growth in the central nervous system by sequestering angiostatin
M Chekenya, M Hjelstuen, PØ Enger, F Thorsen, AL Jacob, B Probst, ...
The FASEB Journal 16 (6), 586-588, 2002
1502002
Targeting the NG2/CSPG4 proteoglycan retards tumour growth and angiogenesis in preclinical models of GBM and melanoma
J Wang, A Svendsen, J Kmiecik, H Immervoll, KO Skaftnesmo, ...
PloS one 6 (7), e23062, 2011
1402011
The NG2 chondoitin sulfate proteoglycan: role in malignant progression of human brain tumours
M Chekenya, HK Rooprai, D Davies, JM Levine, AM Butt, GJ Pilkington
International journal of developmental neuroscience 17 (5-6), 421-435, 1999
1331999
A reproducible brain tumour model established from human glioblastoma biopsies
J Wang, H Miletic, PØ Sakariassen, PC Huszthy, H Jacobsen, N Brekkå, ...
BMC cancer 9, 1-13, 2009
1202009
The glial precursor proteoglycan, NG2, is expressed on tumour neovasculature by vascular pericytes in human malignant brain tumours
M Chekenya, PØ Enger, F Thorsen, BB Tysnes, S Al‐Sarraj, TA Read, ...
Neuropathology and applied neurobiology 28 (5), 367-380, 2002
1192002
Targeting glioblastoma with NK cells and mAb against NG2/CSPG4 prolongs animal survival
A Poli, J Wang, O Domingues, J Planagumà, T Yan, CB Rygh, ...
Oncotarget 4 (9), 1527, 2013
1122013
NG2 precursor cells in neoplasia: functional, histogenesis and therapeutic implications for malignant brain tumours
M Chekenya, GJ Pilkington
Journal of neurocytology 31 (6), 507 ppl=-521, 2002
1122002
NK cells in central nervous system disorders
A Poli, J Kmiecik, O Domingues, F Hentges, M Bléry, M Chekenya, ...
The Journal of Immunology 190 (11), 5355-5362, 2013
1102013
Hyperoxic treatment induces mesenchymal-to-epithelial transition in a rat adenocarcinoma model
I Moen, AM Øyan, KH Kalland, KJ Tronstad, LA Akslen, M Chekenya, ...
PloS one 4 (7), e6381, 2009
972009
Natural killer cells in intracranial neoplasms: presence and therapeutic efficacy against brain tumours
J Kmiecik, J Zimmer, M Chekenya
Journal of Neuro-oncology 116, 1-9, 2014
802014
NG2 expression regulates vascular morphology and function in human brain tumours
C Brekke, A Lundervold, PØ Enger, C Brekken, E Stålsett, TB Pedersen, ...
Neuroimage 29 (3), 965-976, 2006
712006
NK cells with KIR2DS2 immunogenotype have a functional activation advantage to efficiently kill glioblastoma and prolong animal survival
A Gras Navarro, J Kmiecik, L Leiss, M Zelkowski, A Engelsen, Ø Bruserud, ...
The Journal of Immunology 193 (12), 6192-6206, 2014
632014
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