Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma D Chen, I Livne-bar, JL Vanderluit, RS Slack, M Agochiya, R Bremner Cancer cell 5 (6), 539-551, 2004 | 326 | 2004 |
Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms ECC Cheung, L Melanson-Drapeau, SP Cregan, JL Vanderluit, ... Journal of Neuroscience 25 (6), 1324-1334, 2005 | 246 | 2005 |
The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis NG Bérubé, M Mangelsdorf, M Jagla, J Vanderluit, D Garrick, RJ Gibbons, ... The Journal of clinical investigation 115 (2), 258-267, 2005 | 240 | 2005 |
Mcl-1 is a key regulator of apoptosis during CNS development and after DNA damage N Arbour, JL Vanderluit, JN Le Grand, A Jahani-Asl, VA Ruzhynsky, ... Journal of Neuroscience 28 (24), 6068-6078, 2008 | 231 | 2008 |
MCL‐1 is a stress sensor that regulates autophagy in a developmentally regulated manner M Germain, AP Nguyen, JN Le Grand, N Arbour, JL Vanderluit, DS Park, ... The EMBO journal 30 (2), 395-407, 2011 | 206 | 2011 |
Telencephalon-specific Rb knockouts reveal enhanced neurogenesis, survival and abnormal cortical development KL Ferguson, JL Vanderluit, JM Hébert, WC McIntosh, E Tibbo, ... The EMBO journal 21 (13), 3337-3346, 2002 | 193 | 2002 |
Conditional disruption of calpain in the CNS alters dendrite morphology, impairs LTP, and promotes neuronal survival following injury M Amini, C Ma, R Farazifard, G Zhu, Y Zhang, J Vanderluit, JS Zoltewicz, ... Journal of Neuroscience 33 (13), 5773-5784, 2013 | 115 | 2013 |
p107 regulates neural precursor cells in the mammalian brain JL Vanderluit, KL Ferguson, V Nikoletopoulou, M Parker, V Ruzhynsky, ... The Journal of cell biology 166 (6), 853-863, 2004 | 104 | 2004 |
Unique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functions KA McClellan, VA Ruzhynsky, DN Douda, JL Vanderluit, KL Ferguson, ... Molecular and cellular biology 27 (13), 4825-4843, 2007 | 98 | 2007 |
Apoptotic cell death in disease—Current understanding of the NCCD 2023 I Vitale, F Pietrocola, E Guilbaud, SA Aaronson, JM Abrams, D Adam, ... Cell Death & Differentiation 30 (5), 1097-1154, 2023 | 90 | 2023 |
A cell‐autonomous requirement for the cell cycle regulatory protein, Rb, in neuronal migration KL Ferguson, KA McClellan, JL Vanderluit, WC McIntosh, C Schuurmans, ... The EMBO journal 24 (24), 4381-4391, 2005 | 79 | 2005 |
Caspase‐3 is activated following axotomy of neonatal facial motoneurons and caspase‐3 gene deletion delays axotomy‐induced cell death in rodents JL Vanderluit, LT McPhail, KJL Fernandes, CB McBride, C Huguenot, ... European Journal of Neuroscience 12 (10), 3469-3480, 2000 | 69 | 2000 |
The Retinoblastoma family member p107 regulates the rate of progenitor commitment to a neuronal fate JL Vanderluit, CA Wylie, KA McClellan, N Ghanem, A Fortin, S Callaghan, ... The Journal of cell biology 178 (1), 129-139, 2007 | 63 | 2007 |
Axonal reinjury reveals the survival and re-expression of regeneration-associated genes in chronically axotomized adult mouse motoneurons LT McPhail, KJL Fernandes, CCM Chan, JL Vanderluit, W Tetzlaff Experimental neurology 188 (2), 331-340, 2004 | 63 | 2004 |
A reproducible Endothelin-1 model of forelimb motor cortex stroke in the mouse RB Roome, RF Bartlett, M Jeffers, J Xiong, D Corbett, JL Vanderluit Journal of neuroscience methods 233, 34-44, 2014 | 57 | 2014 |
c-Jun N-terminal kinase 3 deficiency protects neurons from axotomy-induced death in vivo through mechanisms independent of c-Jun phosphorylation E Keramaris, JL Vanderluit, M Bahadori, K Mousavi, RJ Davis, R Flavell, ... Journal of Biological Chemistry 280 (2), 1132-1141, 2005 | 56 | 2005 |
Mcl-1 and Bcl-xL are essential for survival of the developing nervous system LC Fogarty, RT Flemmer, BA Geizer, M Licursi, A Karunanithy, ... Cell Death & Differentiation 26 (8), 1501-1515, 2019 | 50 | 2019 |
Paw-dragging: a novel, sensitive analysis of the mouse cylinder test RB Roome, JL Vanderluit JoVE (Journal of Visualized Experiments), e52701, 2015 | 50 | 2015 |
Mcl-1 regulates the survival of adult neural precursor cells CD Malone, SMM Hasan, RB Roome, J Xiong, M Furlong, JT Opferman, ... Molecular and Cellular Neuroscience 49 (4), 439-447, 2012 | 46 | 2012 |
Urine concentrating defect in prostaglandin EP1-deficient mice CRJ Kennedy, H Xiong, S Rahal, J Vanderluit, RS Slack, Y Zhang, ... American Journal of Physiology-Renal Physiology 292 (2), F868-F875, 2007 | 46 | 2007 |