X-chromosome silencing in the germline of C. elegans WG Kelly, CE Schaner, AF Dernburg, MH Lee, SK Kim, AM Villeneuve, ... Development 129 (2), 479-492, 2002 | 397 | 2002 |
Meiotic pairing and imprinted X chromatin assembly in Caenorhabditis elegans CJ Bean, CE Schaner, WG Kelly Nature genetics 36 (1), 100, 2004 | 242 | 2004 |
A conserved chromatin architecture marks and maintains the restricted germ cell lineage in worms and flies CE Schaner, G Deshpande, PD Schedl, WG Kelly Developmental cell 5 (5), 747-757, 2003 | 194 | 2003 |
N-terminal α-methylation of RCC1 is necessary for stable chromatin association and normal mitosis T Chen, TL Muratore, CE Schaner-Tooley, J Shabanowitz, DF Hunt, ... Nature cell biology 9 (5), 596, 2007 | 162 | 2007 |
NRMT is an α-N-methyltransferase that methylates RCC1 and retinoblastoma protein CES Tooley, JJ Petkowski, TL Muratore-Schroeder, JL Balsbaugh, ... Nature 466 (7310), 1125, 2010 | 131 | 2010 |
Germline chromatin CE Schaner, WG Kelly Wormbook, 2006 | 96 | 2006 |
Substrate specificity of mammalian N-terminal α-amino methyltransferase NRMT JJ Petkowski, CE Schaner Tooley, LC Anderson, IA Shumilin, ... Biochemistry 51 (30), 5942-5950, 2012 | 57 | 2012 |
NRMT2 is an N-terminal monomethylase that primes for its homologue NRMT1 JJ Petkowski, LA Bonsignore, JG Tooley, DW Wilkey, ML Merchant, ... Biochemical Journal 456 (3), 453-462, 2013 | 49 | 2013 |
NRMT1 knockout mice exhibit phenotypes associated with impaired DNA repair and premature aging LA Bonsignore, JG Tooley, PM Van Hoose, E Wang, A Cheng, MP Cole, ... Mechanisms of ageing and development 146, 42-52, 2015 | 44 | 2015 |
Loss of the N-terminal methyltransferase NRMT1 increases sensitivity to DNA damage and promotes mammary oncogenesis LA Bonsignore, JS Butler, CM Klinge, CES Tooley Oncotarget 6 (14), 12248, 2015 | 38 | 2015 |
New roles for old modifications: Emerging roles of N‐terminal post‐translational modifications in development and disease JG Tooley, CE Schaner Tooley Protein Science 23 (12), 1641-1649, 2014 | 32 | 2014 |
N-terminal acetylation and methylation differentially affect the function of MYL9 C Nevitt, JG Tooley, CES Tooley Biochemical Journal, BCJ20180638, 2018 | 31 | 2018 |
Select human cancer mutants of NRMT1 alter its catalytic activity and decrease N‐terminal trimethylation KM Shields, JG Tooley, JJ Petkowski, DW Wilkey, NC Garbett, ... Protein Science 26 (8), 1639-1652, 2017 | 25 | 2017 |
BMP-9 dependent pathways required for the chondrogenic differentiation of pluripotent stem cells A Cheng, AR Gustafson, CES Tooley, M Zhang Differentiation 92 (5), 298-305, 2016 | 22 | 2016 |
The N‐terminal methyltransferase homologs NRMT1 and NRMT2 exhibit novel regulation of activity through heterotrimer formation JD Faughn, WL Dean, CE Schaner Tooley Protein Science, 2018 | 14 | 2018 |
Registered report: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate O Fiehn, MR Showalter, CE Schaner-Tooley Elife 5, e12626, 2016 | 11 | 2016 |
Loss of protein targeting to glycogen sensitizes human hepatocellular carcinoma cells towards glucose deprivation mediated oxidative stress and cell death R Yang, M Zhang, AR Gustafson, E Wang, MP Cole, CES Tooley, ... Bioscience reports, BSR20150090, 2015 | 9 | 2015 |
NRMT1 mutants naturally occurring in human cancers have altered catalytic activity and cause a decrease in N-terminal trimethylation levels. KM Shields, JG Tooley, CE Tooley MOLECULAR BIOLOGY OF THE CELL 28, 2017 | | 2017 |
N-terminal protein modifications regulate the activity of Myosin Regulatory Light Chain 9 in colorectal carcinoma cells. CD Nevitt, JG Tooley, CE Tooley MOLECULAR BIOLOGY OF THE CELL 28, 2017 | | 2017 |
Investigating the role of N-terminal protein methylation in colon cancer progression. JG Tooley, JO Trent, CES Tooley Cancer Research 73 (8 Supplement), 5386-5386, 2013 | | 2013 |