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Christine E. Schaner Tooley
Christine E. Schaner Tooley
Assistant Professor of Biochemistry, The State University of New York at Buffalo
Verified email at buffalo.edu
Title
Cited by
Cited by
Year
X-chromosome silencing in the germline of C. elegans
WG Kelly, CE Schaner, AF Dernburg, MH Lee, SK Kim, AM Villeneuve, ...
Development 129 (2), 479-492, 2002
3972002
Meiotic pairing and imprinted X chromatin assembly in Caenorhabditis elegans
CJ Bean, CE Schaner, WG Kelly
Nature genetics 36 (1), 100, 2004
2422004
A conserved chromatin architecture marks and maintains the restricted germ cell lineage in worms and flies
CE Schaner, G Deshpande, PD Schedl, WG Kelly
Developmental cell 5 (5), 747-757, 2003
1942003
N-terminal α-methylation of RCC1 is necessary for stable chromatin association and normal mitosis
T Chen, TL Muratore, CE Schaner-Tooley, J Shabanowitz, DF Hunt, ...
Nature cell biology 9 (5), 596, 2007
1622007
NRMT is an α-N-methyltransferase that methylates RCC1 and retinoblastoma protein
CES Tooley, JJ Petkowski, TL Muratore-Schroeder, JL Balsbaugh, ...
Nature 466 (7310), 1125, 2010
1312010
Germline chromatin
CE Schaner, WG Kelly
Wormbook, 2006
962006
Substrate specificity of mammalian N-terminal α-amino methyltransferase NRMT
JJ Petkowski, CE Schaner Tooley, LC Anderson, IA Shumilin, ...
Biochemistry 51 (30), 5942-5950, 2012
572012
NRMT2 is an N-terminal monomethylase that primes for its homologue NRMT1
JJ Petkowski, LA Bonsignore, JG Tooley, DW Wilkey, ML Merchant, ...
Biochemical Journal 456 (3), 453-462, 2013
492013
NRMT1 knockout mice exhibit phenotypes associated with impaired DNA repair and premature aging
LA Bonsignore, JG Tooley, PM Van Hoose, E Wang, A Cheng, MP Cole, ...
Mechanisms of ageing and development 146, 42-52, 2015
442015
Loss of the N-terminal methyltransferase NRMT1 increases sensitivity to DNA damage and promotes mammary oncogenesis
LA Bonsignore, JS Butler, CM Klinge, CES Tooley
Oncotarget 6 (14), 12248, 2015
382015
New roles for old modifications: Emerging roles of N‐terminal post‐translational modifications in development and disease
JG Tooley, CE Schaner Tooley
Protein Science 23 (12), 1641-1649, 2014
322014
N-terminal acetylation and methylation differentially affect the function of MYL9
C Nevitt, JG Tooley, CES Tooley
Biochemical Journal, BCJ20180638, 2018
312018
Select human cancer mutants of NRMT1 alter its catalytic activity and decrease N‐terminal trimethylation
KM Shields, JG Tooley, JJ Petkowski, DW Wilkey, NC Garbett, ...
Protein Science 26 (8), 1639-1652, 2017
252017
BMP-9 dependent pathways required for the chondrogenic differentiation of pluripotent stem cells
A Cheng, AR Gustafson, CES Tooley, M Zhang
Differentiation 92 (5), 298-305, 2016
222016
The N‐terminal methyltransferase homologs NRMT1 and NRMT2 exhibit novel regulation of activity through heterotrimer formation
JD Faughn, WL Dean, CE Schaner Tooley
Protein Science, 2018
142018
Registered report: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate
O Fiehn, MR Showalter, CE Schaner-Tooley
Elife 5, e12626, 2016
112016
Loss of protein targeting to glycogen sensitizes human hepatocellular carcinoma cells towards glucose deprivation mediated oxidative stress and cell death
R Yang, M Zhang, AR Gustafson, E Wang, MP Cole, CES Tooley, ...
Bioscience reports, BSR20150090, 2015
92015
NRMT1 mutants naturally occurring in human cancers have altered catalytic activity and cause a decrease in N-terminal trimethylation levels.
KM Shields, JG Tooley, CE Tooley
MOLECULAR BIOLOGY OF THE CELL 28, 2017
2017
N-terminal protein modifications regulate the activity of Myosin Regulatory Light Chain 9 in colorectal carcinoma cells.
CD Nevitt, JG Tooley, CE Tooley
MOLECULAR BIOLOGY OF THE CELL 28, 2017
2017
Investigating the role of N-terminal protein methylation in colon cancer progression.
JG Tooley, JO Trent, CES Tooley
Cancer Research 73 (8 Supplement), 5386-5386, 2013
2013
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Articles 1–20