| Identification of Syn-Pimara-7,15-Diene Synthase Reveals Functional Clustering of Terpene Synthases Involved in Rice Phytoalexin/Allelochemical Biosynthesis PR Wilderman, M Xu, Y Jin, RM Coates, RJ Peters Plant physiology 135 (4), 2098-2105, 2004 | 233 | 2004 |
| Rice Contains Two Disparate ent-Copalyl Diphosphate Synthases with Distinct Metabolic Functions S Prisic, M Xu, PR Wilderman, RJ Peters Plant physiology 136 (4), 4228-4236, 2004 | 221 | 2004 |
| A modular approach for facile biosynthesis of labdane-related diterpenes A Cyr, PR Wilderman, M Determan, RJ Peters Journal of the American Chemical Society 129 (21), 6684-6685, 2007 | 188 | 2007 |
| Following evolution's lead to a single residue switch for diterpene synthase product outcome M Xu, PR Wilderman, RJ Peters Proceedings of the National Academy of Sciences 104 (18), 7397-7401, 2007 | 187 | 2007 |
| Functional characterization of the rice kaurene synthase-like gene family M Xu, PR Wilderman, D Morrone, J Xu, A Roy, M Margis-Pinheiro, ... Phytochemistry 68 (3), 312-326, 2007 | 146 | 2007 |
| Crystal structure of a cytochrome P450 2B6 genetic variant in complex with the inhibitor 4-(4-chlorophenyl) imidazole at 2.0-Å resolution SC Gay, MB Shah, JC Talakad, K Maekawa, AG Roberts, PR Wilderman, ... Molecular pharmacology 77 (4), 529-538, 2010 | 105 | 2010 |
| A single residue switch converts abietadiene synthase into a pimaradiene specific cyclase PR Wilderman, RJ Peters Journal of the American Chemical Society 129 (51), 15736-15737, 2007 | 100 | 2007 |
| 16-Aza-ent-beyerane and 16-Aza-ent-trachylobane: Potent Mechanism-Based Inhibitors of Recombinant ent-Kaurene Synthase from Arabidopsis thaliana A Roy, FG Roberts, PR Wilderman, K Zhou, RJ Peters, RM Coates Journal of the American Chemical Society 129 (41), 12453-12460, 2007 | 79 | 2007 |
| Conformational adaptation of human cytochrome P450 2B6 and rabbit cytochrome P450 2B4 revealed upon binding multiple amlodipine molecules MB Shah, PR Wilderman, J Pascual, Q Zhang, CD Stout, JR Halpert Biochemistry 51 (37), 7225-7238, 2012 | 76 | 2012 |
| Plasticity of cytochrome P450 2B4 as investigated by hydrogen-deuterium exchange mass spectrometry and X-ray crystallography PR Wilderman, MB Shah, T Liu, S Li, S Hsu, AG Roberts, DR Goodlett, ... Journal of Biological Chemistry 285 (49), 38602-38611, 2010 | 62 | 2010 |
| Structural and thermodynamic basis of (+)-α-pinene binding to human cytochrome P450 2B6 PR Wilderman, MB Shah, HH Jang, CD Stout, JR Halpert Journal of the American Chemical Society 135 (28), 10433-10440, 2013 | 41 | 2013 |
| Plasticity of CYP2B enzymes: structural and solution biophysical methods P Ross Wilderman, J R Halpert Current drug metabolism 13 (2), 167-176, 2012 | 40 | 2012 |
| Structural Analysis of Mammalian Cytochrome P450 2B4 Covalently Bound to the Mechanism-Based Inactivator tert-Butylphenylacetylene: Insight into Partial … SC Gay, H Zhang, PR Wilderman, AG Roberts, T Liu, S Li, H Lin, Q Zhang, ... Biochemistry 50 (22), 4903-4911, 2011 | 40 | 2011 |
| Investigation by site‐directed mutagenesis of the role of cytochrome P450 2B4 non‐active‐site residues in protein–ligand interactions based on crystal structures of the ligand … PR Wilderman, SC Gay, HH Jang, Q Zhang, CD Stout, JR Halpert The FEBS journal 279 (9), 1607-1620, 2012 | 34 | 2012 |
| Rational engineering of cytochromes P450 2B6 and 2B11 for enhanced stability: Insights into structural importance of residue 334 JC Talakad, PR Wilderman, DR Davydov, S Kumar, JR Halpert Archives of biochemistry and biophysics 494 (2), 151-158, 2010 | 30 | 2010 |
| Structural and biophysical characterization of human cytochromes P450 2B6 and 2A6 bound to volatile hydrocarbons: analysis and comparison MB Shah, PR Wilderman, J Liu, HH Jang, Q Zhang, CD Stout, JR Halpert Molecular pharmacology 87 (4), 649-659, 2015 | 21 | 2015 |
| Role of cytochrome P450 2B sequence variation and gene copy number in facilitating dietary specialization in mammalian herbivores S Kitanovic, TJ Orr, D Spalink, GB Cocke, K Schramm, PR Wilderman, ... Molecular Ecology 27 (3), 723-736, 2018 | 20 | 2018 |
| Structure-function analysis of mammalian CYP2B enzymes using 7-substituted coumarin derivatives as probes: utility of crystal structures and molecular modeling in understanding … MB Shah, J Liu, L Huo, Q Zhang, MD Dearing, PR Wilderman, GD Szklarz, ... Molecular Pharmacology 89 (4), 435-445, 2016 | 17 | 2016 |
| Functional characterization of cytochromes P450 2B from the desert woodrat Neotoma lepida PR Wilderman, HH Jang, JR Malenke, M Salib, E Angermeier, S Lamime, ... Toxicology and applied pharmacology 274 (3), 393-401, 2014 | 15 | 2014 |
| Coumarin derivatives as substrate probes of mammalian cytochromes P450 2B4 and 2B6: assessing the importance of 7-alkoxy chain length, halogen substitution, and non-active site … J Liu, MB Shah, Q Zhang, CD Stout, JR Halpert, PR Wilderman Biochemistry 55 (13), 1997-2007, 2016 | 13 | 2016 |
