A single dose of self-transcribing and replicating RNA-based SARS-CoV-2 vaccine produces protective adaptive immunity in mice R De Alwis, ES Gan, S Chen, YS Leong, HC Tan, SL Zhang, C Yau, ... Molecular Therapy 29 (6), 1970-1983, 2021 | 149 | 2021 |
Kinetic redistribution of native and misfolded RNAs by a DEAD-box chaperone H Bhaskaran, R Russell Nature 449 (7165), 1014-1018, 2007 | 138 | 2007 |
Nonspecific binding to structured RNA and preferential unwinding of an exposed helix by the CYT-19 protein, a DEAD-box RNA chaperone P Tijerina, H Bhaskaran, R Russell Proceedings of the National Academy of Sciences 103 (45), 16698-16703, 2006 | 117 | 2006 |
Probing the mechanisms of DEAD-box proteins as general RNA chaperones: the C-terminal domain of CYT-19 mediates general recognition of RNA JK Grohman, M Del Campo, H Bhaskaran, P Tijerina, AM Lambowitz, ... Biochemistry 46 (11), 3013-3022, 2007 | 90 | 2007 |
Do DEAD-box proteins promote group II intron splicing without unwinding RNA? M Del Campo, P Tijerina, H Bhaskaran, S Mohr, Q Yang, E Jankowsky, ... Molecular cell 28 (1), 159-166, 2007 | 82 | 2007 |
The ATPase Fap7 tests the ability to carry out translocation-like conformational changes and releases Dim1 during 40S ribosome maturation H Ghalei, J Trepreau, JC Collins, H Bhaskaran, BS Strunk, K Karbstein Molecular cell 67 (6), 990-1000. e3, 2017 | 62 | 2017 |
Kinetics of tRNA folding monitored by aminoacylation H Bhaskaran, A Rodriguez-Hernandez, JJ Perona Rna 18 (3), 569-580, 2012 | 45 | 2012 |
Deletion of the P5abc Peripheral Element Accelerates Early and Late Folding Steps of the Tetrahymena Group I Ribozyme R Russell, P Tijerina, AB Chadee, H Bhaskaran Biochemistry 46 (17), 4951-4961, 2007 | 29 | 2007 |
DEAD-box protein CYT-19 is activated by exposed helices in a group I intron RNA I Jarmoskaite, H Bhaskaran, S Seifert, R Russell Proceedings of the National Academy of Sciences 111 (29), E2928-E2936, 2014 | 27 | 2014 |
Two-step aminoacylation of tRNA without channeling in Archaea H Bhaskaran, JJ Perona Journal of molecular biology 411 (4), 854-869, 2011 | 25 | 2011 |
Synthesis of Glu-tRNAGln by Engineered and Natural Aminoacyl-tRNA Synthetases A Rodríguez-Hernández, H Bhaskaran, A Hadd, JJ Perona Biochemistry 49 (31), 6727-6736, 2010 | 25 | 2010 |
Structural dynamics of a mitochondrial tRNA possessing weak thermodynamic stability H Bhaskaran, T Taniguchi, T Suzuki, T Suzuki, JJ Perona Biochemistry 53 (9), 1456-1465, 2014 | 11 | 2014 |
Protein roles in group I intron RNA folding: the tyrosyl-tRNA synthetase CYT-18 stabilizes the native state relative to a long-lived misfolded structure without compromising … AB Chadee, H Bhaskaran, R Russell Journal of molecular biology 395 (3), 656-670, 2010 | 11 | 2010 |
In vitro selection of enteric microflora for potential use as a competitive exclusion culture against Campylobacter in poultry HP Bhaskaran, AM Donoghue, K Arsi, A Wooming, I Reyes-Herrera, ... Int. J. Poult. Sci 10 (12), 940-945, 2011 | 9 | 2011 |
mRNA therapy for ornithine transcarbamylase deficiency M Sablad, Y Bao, J Vega, H Bhaskaran, C Perez-Garcia, J Gonzalez, ... Society for Inherited Metabolic Disorders (SIMD) Conference, 2019 | 1 | 2019 |
Compositions and methods for treating phenylketonuria K Tachikawa, CG Perez-garcia, P Chivukula, H Bhaskaran, SC Daugherty, ... US Patent 11,939,600, 2024 | | 2024 |
Method of purifying mRNA using substrate dependent ribozyme and solid-support attachment tag H Bhaskaran US Patent App. 18/072,674, 2023 | | 2023 |
Therapeutics for glycogen storage disease type iii K Tachikawa, CG Perez-garcia, P Chivukula, H Bhaskaran, CW Cobaugh, ... US Patent App. 17/736,798, 2022 | | 2022 |
Therapeutics for glycogen storage disease type III K Tachikawa, CG Perez-garcia, P Chivukula, H Bhaskaran, CW Cobaugh, ... US Patent 11,377,643, 2022 | | 2022 |
THERAPEUTIC AGENTS FOR GLYCOGEN STORAGE DISEASE TYPE III K Tachikawa, CG PEREZ-GARCIA, P Chivukula, HP BHASKARAN, ... | | 2021 |