| Phenylbutyrate ameliorates cognitive deficit and reduces tau pathology in an Alzheimer's disease mouse model A Ricobaraza, M Cuadrado-Tejedor, A Pérez-Mediavilla, D Frechilla, ... Neuropsychopharmacology 34 (7), 1721-1732, 2009 | 438 | 2009 |
| Phenylbutyrate rescues dendritic spine loss associated with memory deficits in a mouse model of Alzheimer disease A Ricobaraza, M Cuadrado‐Tejedor, S Marco, I Pérez‐Otaño, ... Hippocampus 22 (5), 1040-1050, 2012 | 285 | 2012 |
| Phosphodiesterases as therapeutic targets for Alzheimer's disease A García-Osta, M Cuadrado-Tejedor, C García-Barroso, J Oyarzabal, ... ACS chemical neuroscience 3 (11), 832-844, 2012 | 258 | 2012 |
| Rosiglitazone rescues memory impairment in Alzheimer's transgenic mice: mechanisms involving a reduced amyloid and tau pathology L Escribano, AM Simón, E Gimeno, M Cuadrado-Tejedor, ... Neuropsychopharmacology 35 (7), 1593-1604, 2010 | 256 | 2010 |
| Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice. GIT Ribé EM, Pérez M, Puig B, Gich I, Lim F, Cuadrado M, Sesma T, Catena S ... Neurobiol Dis. 20 (3), 814-822, 2005 | 219 | 2005 |
| Sildenafil restores cognitive function without affecting β‐amyloid burden in a mouse model of Alzheimer's disease M Cuadrado‐Tejedor, I Hervias, A Ricobaraza, E Puerta, ... British journal of pharmacology 164 (8), 2029-2041, 2011 | 205 | 2011 |
| Tadalafil crosses the blood–brain barrier and reverses cognitive dysfunction in a mouse model of AD C García-Barroso, A Ricobaraza, M Pascual-Lucas, N Unceta, AJ Rico, ... Neuropharmacology 64, 114-123, 2013 | 173 | 2013 |
| Early changes in hippocampal Eph receptors precede the onset of memory decline in mouse models of Alzheimer's disease AM Simón, RL De Maturana, A Ricobaraza, L Escribano, L Schiapparelli, ... Journal of Alzheimer's Disease 17 (4), 773-786, 2009 | 145 | 2009 |
| Insulin‐like growth factor 2 reverses memory and synaptic deficits in APP transgenic mice M Pascual‐Lucas, S Viana da Silva, M Di Scala, C Garcia‐Barroso, ... EMBO molecular medicine 6 (10), 1246-1262, 2014 | 135 | 2014 |
| Overexpression of wild-type human APP in mice causes cognitive deficits and pathological features unrelated to Aβ levels AM Simón, L Schiapparelli, P Salazar-Colocho, M Cuadrado-Tejedor, ... Neurobiology of disease 33 (3), 369-378, 2009 | 130 | 2009 |
| Enhanced expression of the voltage-dependent anion channel 1 (VDAC1) in Alzheimer's disease transgenic mice: an insight into the pathogenic effects of amyloid-β M Cuadrado-Tejedor, M Vilarino, F Cabodevilla, J Del Río, D Frechilla, ... Journal of Alzheimer's disease 23 (2), 195-206, 2011 | 123 | 2011 |
| Increased sensitivity to MPTP in human alpha-synuclein A30P transgenic mice. GIT Nieto M, Gil-Bea FJ, Dalfó E, Cuadrado M, Cabodevilla F, Sánchez B ... Neurobiol Aging. 27 (6), 848-856, 2006 | 121 | 2006 |
| Expression of stress-activated kinases c-Jun N-terminal kinase (SAPK/JNK-P) and p38 kinase (p38-P), and tau hyperphosphorylation in neurites surrounding betaA plaques in APP … FI Puig B, Gómez-Isla T, Ribé E, Cuadrado M, Torrejón-Escribano B, Dalfó E Neuropathol Appl Neurobiol. 30 (5), 491-502, 2004 | 118 | 2004 |
| Decreased levels of guanosine 3′, 5′‐monophosphate (c GMP) in cerebrospinal fluid (CSF) are associated with cognitive decline and amyloid pathology in A lzheimer's disease A Ugarte, F Gil‐Bea, C García‐Barroso, Á Cedazo‐Minguez, MJ Ramírez, ... Neuropathology and applied neurobiology 41 (4), 471-482, 2015 | 97 | 2015 |
| A first-in-class small-molecule that acts as a dual inhibitor of HDAC and PDE5 and that rescues hippocampal synaptic impairment in Alzheimer’s disease mice M Cuadrado-Tejedor, C Garcia-Barroso, JA Sánchez-Arias, O Rabal, ... Neuropsychopharmacology 42 (2), 524-539, 2017 | 96 | 2017 |
| Targeting RNA-mediated toxicity in C9orf72 ALS and/or FTD by RNAi-based gene therapy R Martier, JM Liefhebber, A García-Osta, J Miniarikova, ... Molecular Therapy-Nucleic Acids 16, 26-37, 2019 | 83 | 2019 |
| Design, synthesis, and biological evaluation of first-in-class dual acting histone deacetylases (HDACs) and phosphodiesterase 5 (PDE5) inhibitors for the treatment of Alzheimer … O Rabal, JA Sánchez-Arias, M Cuadrado-Tejedor, I de Miguel, ... Journal of Medicinal Chemistry 59 (19), 8967-9004, 2016 | 81 | 2016 |
| Sildenafil protects against 3-nitropropionic acid neurotoxicity through the modulation of calpain, CREB, and BDNF E Puerta, I Hervias, L Barros-Miñones, J Jordan, A Ricobaraza, ... Neurobiology of disease 38 (2), 237-245, 2010 | 81 | 2010 |
| Chronic mild stress accelerates the onset and progression of the Alzheimer's disease phenotype in Tg2576 mice M Cuadrado-Tejedor, A Ricobaraza, D Frechilla, R Franco, ... Journal of Alzheimer's Disease 28 (3), 567-578, 2012 | 74 | 2012 |
| Phenylbutyrate is a multifaceted drug that exerts neuroprotective effects and reverses the Alzheimer s disease-like phenotype of a commonly used mouse model M Cuadrado-Tejedor, A L Ricobaraza, R Torrijo, R Franco, A Garcia-Osta Current pharmaceutical design 19 (28), 5076-5084, 2013 | 73 | 2013 |
