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Charlotte E Farquhar
Charlotte E Farquhar
Verified email at mit.edu
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Molecular and behavioral pharmacological characterization of abused synthetic cannabinoids MMB-and MDMB-FUBINACA, MN-18, NNEI, CUMYL-PICA, and 5-Fluoro-CUMYL-PICA
TF Gamage, CE Farquhar, TW Lefever, JA Marusich, RC Kevin, ...
Journal of Pharmacology and Experimental Therapeutics 365 (2), 437-446, 2018
742018
Sex, THC, and hormones: Effects on density and sensitivity of CB1 cannabinoid receptors in rats
CE Farquhar, CS Breivogel, TF Gamage, EA Gay, BF Thomas, RM Craft, ...
Drug and alcohol dependence 194, 20-27, 2019
612019
Synthetic cannabinoid hydroxypentyl metabolites retain efficacy at human cannabinoid receptors
TF Gamage, CE Farquhar, RJ McKinnie, RC Kevin, IS McGregor, ...
Journal of Pharmacology and Experimental Therapeutics 368 (3), 414-422, 2019
432019
Sex, species and age: Effects of rodent demographics on the pharmacology of∆ 9-tetrahydrocanabinol
JL Wiley, DG Barrus, CE Farquhar, TW Lefever, TF Gamage
Progress in Neuro-Psychopharmacology and Biological Psychiatry 106, 110064, 2021
342021
The great divide: separation between in vitro and in vivo effects of PSNCBAM-based CB1 receptor allosteric modulators
TF Gamage, CE Farquhar, TW Lefever, BF Thomas, T Nguyen, Y Zhang, ...
Neuropharmacology 125, 365-375, 2017
252017
Cell-penetrating peptides enhance peptide vaccine accumulation and persistence in lymph nodes to drive immunogenicity
CM Backlund, RL Holden, KD Moynihan, D Garafola, C Farquhar, ...
Proceedings of the National Academy of Sciences 119 (32), e2204078119, 2022
242022
Novel diarylurea based allosteric modulators of the cannabinoid CB1 receptor: evaluation of importance of 6-pyrrolidinylpyridinyl substitution
T Nguyen, N German, AM Decker, TL Langston, TF Gamage, ...
Journal of medicinal chemistry 60 (17), 7410-7424, 2017
242017
Automated flow synthesis of peptide–PNA conjugates
C Li, AJ Callahan, KS Phadke, B Bellaire, CE Farquhar, G Zhang, ...
ACS central science 8 (2), 205-213, 2021
192021
Palladium-mediated incorporation of carboranes into small molecules, peptides, and proteins
M Gazvoda, HH Dhanjee, J Rodriguez, JS Brown, CE Farquhar, NL Truex, ...
Journal of the American Chemical Society 144 (17), 7852-7860, 2022
162022
Targeting glioblastoma using a novel peptide specific to a deglycosylated isoform of brevican
N von Spreckelsen, CM Fadzen, N Hartrampf, Y Ghotmi, JM Wolfe, ...
Advanced therapeutics 4 (4), 2000244, 2021
122021
Secondary Amino Alcohols: Traceless Cleavable Linkers for Use in Affinity Capture and Release
S Pomplun, CR Shugrue, AM Schmitt, CK Schissel, CE Farquhar, ...
Angewandte Chemie International Edition 59 (28), 11566-11572, 2020
102020
Diarylureas Containing 5-Membered Heterocycles as CB1 Receptor Allosteric Modulators: Design, Synthesis, and Pharmacological Evaluation
T Nguyen, TF Gamage, AM Decker, N German, TL Langston, ...
ACS chemical neuroscience 10 (1), 518-527, 2018
102018
A Tumor-Homing Peptide Platform Enhances Drug Solubility, Improves Blood–Brain Barrier Permeability and Targets Glioblastoma
CF Cho, CE Farquhar, CM Fadzen, B Scott, P Zhuang, N von Spreckelsen, ...
Cancers 14 (9), 2207, 2022
92022
A Pt (IV)-conjugated brain penetrant macrocyclic peptide shows pre-clinical efficacy in glioblastoma
JL Jimenez-Macias, YC Lee, E Miller, T Finkelberg, M Zdioruk, G Berger, ...
Journal of Controlled Release 352, 623-636, 2022
62022
Cell-Penetrating d-Peptides Retain Antisense Morpholino Oligomer Delivery Activity
CK Schissel, CE Farquhar, AB Malmberg, A Loas, BL Pentelute
ACS Bio & Med Chem Au 2 (2), 150-160, 2022
52022
In-cell penetration selection—mass spectrometry produces noncanonical peptides for antisense delivery.
C Schissel, C Farquhar, AB Malmberg, A Loas, B Pentelute
ACS Chemical Biology, 2023
32023
Automated Fast-Flow Synthesis of Chromosome 9 Open Reading Frame 72 Dipeptide Repeat Proteins
K Sato, CE Farquhar, J Rodriguez, BL Pentelute
Journal of the American Chemical Society 145 (24), 12992-12997, 2023
12023
Automated Fast-Flow Synthesis of C9orf72 Dipeptide Repeat Proteins
K Sato, CE Farquhar, B Pentelute
2023
Automated Fast-Flow Synthesis of Peptide Nucleic Acid Conjugates
C Li, AJ Callahan, KS Phadke, B Bellaire, CE Farquhar, G Zhang, ...
2021
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Articles 1–19