| Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation T Visnes, A Cázares-Körner, W Hao, O Wallner, G Masuyer, O Loseva, ... Science 362 (6416), 834-839, 2018 | 193 | 2018 |
| Uracil in DNA and its processing by different DNA glycosylases T Visnes, B Doseth, HS Pettersen, L Hagen, MML Sousa, M Akbari, ... Philosophical Transactions of the Royal Society B: Biological Sciences 364 …, 2008 | 153 | 2008 |
| Mitochondrial base excision repair of uracil and AP sites takes place by single-nucleotide insertion and long-patch DNA synthesis M Akbari, T Visnes, HE Krokan, M Otterlei DNA repair 7 (4), 605-616, 2008 | 147 | 2008 |
| Validation and development of MTH1 inhibitors for treatment of cancer UW Berglund, K Sanjiv, H Gad, C Kalderen, T Koolmeister, T Pham, ... Annals of oncology 27 (12), 2275-2283, 2016 | 140 | 2016 |
| UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation HS Pettersen, T Visnes, CB Vågbø, EK Svaasand, B Doseth, ... Nucleic acids research 39 (19), 8430-8444, 2011 | 139 | 2011 |
| The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2′-deoxycytidine lesions ML Orta, A Höglund, JM Calderón-Montaño, I Domínguez, ... Nucleic acids research 42 (14), 9108-9120, 2014 | 89 | 2014 |
| AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature HS Pettersen, A Galashevskaya, B Doseth, MML Sousa, A Sarno, ... DNA repair 25, 60-71, 2015 | 86 | 2015 |
| Uracil-DNA Glycosylase in Base Excision Repair and Adaptive Immunity SPECIES DIFFERENCES BETWEEN MAN AND MOUSE B Doseth, T Visnes, A Wallenius, I Ericsson, A Sarno, HS Pettersen, ... Journal of Biological Chemistry 286 (19), 16669-16680, 2011 | 60 | 2011 |
| The rate of base excision repair of uracil is controlled by the initiating glycosylase T Visnes, M Akbari, L Hagen, G Slupphaug, HE Krokan DNA repair 7 (11), 1869-1881, 2008 | 58 | 2008 |
| A Children’s Health Perspective on Nano-and Microplastics K Sripada, A Wierzbicka, K Abass, JO Grimalt, A Erbe, HB Röllin, P Weihe, ... Environmental Health Perspectives 130 (1), 015001, 2022 | 53 | 2022 |
| Targeting BER enzymes in cancer therapy T Visnes, M Grube, BMF Hanna, C Benitez-Buelga, A Cázares-Körner, ... DNA repair 71, 118-126, 2018 | 53 | 2018 |
| Discovery of the first potent and selective inhibitors of human dCTP pyrophosphatase 1 S Llona-Minguez, A Hoglund, SA Jacques, L Johansson, ... Journal of medicinal chemistry 59 (3), 1140-1148, 2016 | 45 | 2016 |
| A regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination E Enervald, L Du, T Visnes, A Björkman, E Lindgren, J Wincent, G Borck, ... Journal of Experimental Medicine 210 (12), 2503-2513, 2013 | 44 | 2013 |
| Targeting OGG1 arrests cancer cell proliferation by inducing replication stress T Visnes, C Benítez-Buelga, A Cázares-Körner, K Sanjiv, BMF Hanna, ... Nucleic Acids Research 48 (21), 12234-12251, 2020 | 41 | 2020 |
| Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates methotrexate anticancer effects JM Baquero, C Benítez-Buelga, V Rajagopal, Z Zhenjun, R Torres-Ruiz, ... Scientific Reports 11 (1), 3490, 2021 | 26 | 2021 |
| Novel Broad-Spectrum Antiviral Inhibitors Targeting Host Factors Essential for Replication of Pathogenic RNA Viruses M Tampere, A Pettke, C Salata, O Wallner, T Koolmeister, ... Viruses 12 (12), 1423, 2020 | 26 | 2020 |
| Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function M Michel, C Benítez-Buelga, PA Calvo, BMF Hanna, O Mortusewicz, ... Science 376 (6600), 1471-1476, 2022 | 25 | 2022 |
| Localisation of the SMC loading complex Nipbl/Mau2 during mammalian meiotic prophase I T Visnes, F Giordano, A Kuznetsova, JA Suja, AD Lander, AL Calof, ... Chromosoma 123, 239-252, 2014 | 24 | 2014 |
| Computational and Experimental Druggability Assessment of Human DNA Glycosylases M Michel, T Visnes, EJ Homan, B Seashore-Ludlow, M Hedenström, ... ACS omega 4 (7), 11642-11656, 2019 | 23 | 2019 |
| MTH1 promotes mitotic progression to avoid oxidative DNA damage in cancer cells H Gad, O Mortusewicz, SG Rudd, A Stolz, N Amaral, L Brautigham, ... BioRxiv, 575290, 2019 | 21 | 2019 |
Thomas HelledayKarolinska InstitutetVerified email at ki.se
