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Jacob J. Hughey
Jacob J. Hughey
Biomedical Informatics at Vanderbilt
Verified email at vanderbilt.edu - Homepage
Title
Cited by
Cited by
Year
Single-cell NF-κB dynamics reveal digital activation and analogue information processing
S Tay, JJ Hughey, TK Lee, T Lipniacki, SR Quake, MW Covert
Nature 466 (7303), 267-271, 2010
9482010
High-sensitivity measurements of multiple kinase activities in live single cells
S Regot, JJ Hughey, BT Bajar, S Carrasco, MW Covert
Cell 157 (7), 1724-1734, 2014
5422014
Guidelines for genome-scale analysis of biological rhythms
ME Hughes, KC Abruzzi, R Allada, R Anafi, AB Arpat, G Asher, P Baldi, ...
Journal of biological rhythms 32 (5), 380-393, 2017
2242017
Phenotype risk scores identify patients with unrecognized Mendelian disease patterns
L Bastarache, JJ Hughey, S Hebbring, J Marlo, W Zhao, WT Ho, ...
Science 359 (6381), 1233-1239, 2018
1922018
A noisy paracrine signal determines the cellular NF-κB response to lipopolysaccharide
TK Lee, EM Denny, JC Sanghvi, JE Gaston, ND Maynard, JJ Hughey, ...
Science signaling 2 (93), ra65-ra65, 2009
1822009
Microfluidic platform for real-time signaling analysis of multiple single T cells in parallel
S Faley, K Seale, J Hughey, DK Schaffer, S VanCompernolle, B McKinney, ...
Lab on a Chip 8 (10), 1700-1712, 2008
1762008
Releasing a preprint is associated with more attention and citations for the peer-reviewed article
DY Fu, JJ Hughey
Elife 8, e52646, 2019
1342019
Robust meta-analysis of gene expression using the elastic net
JJ Hughey, AJ Butte
Nucleic Acids Research 43 (12), e79, 2015
1322015
Population-level rhythms in human skin with implications for circadian medicine
G Wu, MD Ruben, RE Schmidt, LJ Francey, DF Smith, RC Anafi, ...
Proceedings of the National Academy of Sciences 115 (48), 12313-12318, 2018
1122018
Live-cell measurements of kinase activity in single cells using translocation reporters
T Kudo, S Jeknić, DN Macklin, S Akhter, JJ Hughey, S Regot, MW Covert
Nature protocols 13 (1), 155-169, 2018
1042018
ZeitZeiger: supervised learning for high-dimensional data from an oscillatory system
JJ Hughey, T Hastie, AJ Butte
Nucleic acids research 44 (8), e80-e80, 2016
902016
Evidence for widespread dysregulation of circadian clock progression in human cancer
J Shilts, G Chen, JJ Hughey
PeerJ 6, e4327, 2018
802018
Computational modeling of mammalian signaling networks
JJ Hughey, TK Lee, MW Covert
Wiley Interdisciplinary Reviews: Systems Biology and Medicine 2 (2), 194-209, 2010
742010
Machine learning identifies a compact gene set for monitoring the circadian clock in human blood
JJ Hughey
Genome medicine 9, 1-11, 2017
642017
LimoRhyde: a flexible approach for differential analysis of rhythmic transcriptome data
JM Singer, JJ Hughey
Journal of biological rhythms 34 (1), 5-18, 2019
632019
Single-cell variation leads to population invariance in NF-κB signaling dynamics
JJ Hughey, MV Gutschow, BT Bajar, MW Covert
Molecular biology of the cell 26 (3), 583-590, 2015
552015
NF-κB signaling dynamics is controlled by a dose-sensing autoregulatory loop
MM DeFelice, HR Clark, JJ Hughey, I Maayan, T Kudo, MV Gutschow, ...
Science signaling 12 (579), eaau3568, 2019
532019
MetaCyto: a tool for automated meta-analysis of mass and flow cytometry data
Z Hu, C Jujjavarapu, JJ Hughey, S Andorf, HC Lee, PF Gherardini, ...
Cell reports 24 (5), 1377-1388, 2018
512018
Self-reported dietary adherence, disease-specific symptoms, and quality of life are associated with healthcare provider follow-up in celiac disease
JJ Hughey, BK Ray, AR Lee, KN Voorhees, CP Kelly, D Schuppan
BMC gastroenterology 17, 1-8, 2017
492017
Eating breakfast and avoiding late-evening snacking sustains lipid oxidation
KP Kelly, OP McGuinness, M Buchowski, JJ Hughey, H Chen, J Powers, ...
PLoS biology 18 (2), e3000622, 2020
412020
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Articles 1–20