| Lessons learned from the clinical development and market authorization of Glybera LM Bryant, DM Christopher, AR Giles, C Hinderer, JL Rodriguez, JB Smith, ... Human gene therapy Clinical development 24 (2), 55-64, 2013 | 270 | 2013 |
| Adeno-associated virus serotypes 1, 8, and 9 share conserved mechanisms for anterograde and retrograde axonal transport MJ Castle, ZT Gershenson, AR Giles, ELF Holzbaur, JH Wolfe Human gene therapy 25 (8), 705-720, 2014 | 177 | 2014 |
| Deamidation of amino acids on the surface of adeno-associated virus capsids leads to charge heterogeneity and altered vector function AR Giles, JJ Sims, KB Turner, L Govindasamy, MR Alvira, M Lock, ... Molecular therapy 26 (12), 2848-2862, 2018 | 82 | 2018 |
| TLR9 signaling mediates adaptive immunity following systemic AAV gene therapy SN Ashley, S Somanathan, AR Giles, JM Wilson Cellular immunology 346, 103997, 2019 | 44 | 2019 |
| Mapping an adeno-associated virus 9-specific neutralizing epitope to develop next-generation gene delivery vectors AR Giles, L Govindasamy, S Somanathan, JM Wilson Journal of virology 92 (20), 10.1128/jvi. 01011-18, 2018 | 44 | 2018 |
| Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors BS Hollidge, HB Carroll, R Qian, ML Fuller, AR Giles, AC Mercer, ... Frontiers in Neurology 13, 1051559, 2022 | 7 | 2022 |
| Isolating human monoclonal antibodies against adeno-associated virus from donors with pre-existing immunity AR Giles, R Calcedo, AP Tretiakova, JM Wilson Frontiers in immunology 11, 543904, 2020 | 7 | 2020 |
| Significant Differences in Capsid Properties and Potency Between Adeno-Associated Virus Vectors Produced in Sf9 and HEK293 Cells A Giles, M Lock, SJ Chen, K Turner, G Wesolowski, A Prongay, BN Petkov, ... Human Gene Therapy 34 (19-20), 1003-1021, 2023 | 4 | 2023 |
| GluK2 Is a Target for Gene Therapy in Drug‐Resistant Temporal Lobe Epilepsy C Boileau, S Deforges, A Peret, D Scavarda, F Bartolomei, A Giles, ... Annals of Neurology 94 (4), 745-761, 2023 | 2 | 2023 |
| Characterization and biodistribution of under-employed gene therapy vector AAV7 SA Yost, E Firlar, JD Glenn, HB Carroll, S Foltz, AR Giles, JM Egley, ... Journal of Virology 97 (11), e01163-23, 2023 | 1 | 2023 |
| AAV Serotypes 1, 8, and 9 Share a Conserved Mechanism for Axonal Transport but Exhibit Differences in Distal Gene Transfer In Vivo MJ Castle, A Giles, ELF Holzbaur, JH Wolfe Molecular Therapy 21, S48-S48, 2013 | 1 | 2013 |
| Vektor adeno-asociranih virusa (aav) iz podgrupe fi njegove upotrebe JM Wilson, Q Wang, A Giles, K Turner | | 2024 |
| Klade f adeno-associeret virus (aav) vektor og anvendelse deraf JM Wilson, Q Wang, A Giles, K Turner | | 2024 |
| Kladin f adenoassosioitunut virus (aav)-vektori ja sen käyttötapoja J Wilson, Q Wang, A Giles, K Turner | | 2024 |
| Comparative analysis of tropism of a large pool of AAV capsids in cell culture, mice, and non-human primates AC Mercer, AR Giles, SA Yost, E Firnberg, S Cho, S Tejada, J Egley, ... HUMAN GENE THERAPY 33 (23-24), A31-A31, 2022 | | 2022 |
| Evaluation of tissue specific promoters for liver or muscle gene transfer R Qian, SJ Foltz, K Elliott, I Hafiz, S Cho, T Nguyen, W Henry, R Clarke, ... HUMAN GENE THERAPY 33 (23-24), A33-A34, 2022 | | 2022 |
| Biodistribution and safety of a novel AAV9 gene therapy for treatment of temporal lobe epilepsy shown in non-human primates N Pearson, A Borta, A Giles, J Sims, C He, B Gaub, J Smith, A Mercer, ... HUMAN GENE THERAPY 33 (23-24), A78-A78, 2022 | | 2022 |
| A Novel Peptide Insertion into VR-IV or VR-VIII of AAV9 Improves Transduction Strength and Penetration Depth Upon Intravitreal Injection WH Lee, SA Yost, J Gumerson, H Carroll, R Clarke, A Giles, G Trost, ... MOLECULAR THERAPY 30 (4), 247-248, 2022 | | 2022 |
| VP1 Unique and VP1/2 Shared Region Serotype Swap Hybrids Enhance Desirable AAV Properties SA Yost, R Qian, AR Giles, S Cho, B Wu, A Zhang, JM Egley, E Firnberg, ... MOLECULAR THERAPY 30 (4), 238-238, 2022 | | 2022 |
| A Longitudinal, Comparative Analysis of Transgene Expression Durability via Different Promoters in the Striatum of Mice Delivered by Intraparenchymal Injection of rAAV9 BS Hollidge, HB Carroll, AR Giles, A Mercer, O Danos, Y Liu, JT Bruder, ... MOLECULAR THERAPY 30 (4), 423-424, 2022 | | 2022 |
