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Guangwu Zhu
Guangwu Zhu
Johns Hopkins School Medicine
Verified email at jhmi.edu
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Year
BRAF V600E and TERT promoter mutations cooperatively identify the most aggressive papillary thyroid cancer with highest recurrence
M Xing, R Liu, X Liu, AK Murugan, G Zhu, MA Zeiger, S Pai, J Bishop
Journal of clinical oncology 32 (25), 2718, 2014
7532014
TERT Promoter Mutations and Their Association with BRAF V600E Mutation and Aggressive Clinicopathological Characteristics of Thyroid Cancer
X Liu, S Qu, R Liu, C Sheng, X Shi, G Zhu, AK Murugan, H Guan, H Yu, ...
The Journal of Clinical Endocrinology & Metabolism 99 (6), E1130-E1136, 2014
3462014
Mortality risk stratification by combining BRAF V600E and TERT promoter mutations in papillary thyroid cancer: genetic duet of BRAF and TERT promoter mutations in thyroid …
R Liu, J Bishop, G Zhu, T Zhang, PW Ladenson, M Xing
JAMA oncology 3 (2), 202-208, 2017
2572017
High prevalence and mutual exclusivity of genetic alterations in the phosphatidylinositol-3-kinase/akt pathway in thyroid tumors
Y Wang, P Hou, H Yu, W Wang, M Ji, S Zhao, S Yan, X Sun, D Liu, B Shi, ...
The Journal of Clinical Endocrinology & Metabolism 92 (6), 2387-2390, 2007
2082007
Patient age–associated mortality risk is differentiated by BRAF V600E status in papillary thyroid cancer
X Shen, G Zhu, R Liu, D Viola, R Elisei, E Puxeddu, L Fugazzola, ...
Journal of Clinical Oncology 36 (5), 438, 2018
1062018
The prognostic value of tumor multifocality in clinical outcomes of papillary thyroid cancer
F Wang, X Yu, X Shen, G Zhu, Y Huang, R Liu, D Viola, R Elisei, ...
The Journal of Clinical Endocrinology & Metabolism 102 (9), 3241-3250, 2017
1012017
Association of TERT Promoter Mutation 1,295,228 C>T With BRAF V600E Mutation, Older Patient Age, and Distant Metastasis in Anaplastic Thyroid Cancer
X Shi, R Liu, S Qu, G Zhu, J Bishop, X Liu, H Sun, Z Shan, E Wang, Y Luo, ...
The Journal of Clinical Endocrinology & Metabolism 100 (4), E632-E637, 2015
962015
The genetic duet of BRAF V600E and TERT promoter mutations robustly predicts loss of radioiodine avidity in recurrent papillary thyroid cancer
J Liu, R Liu, X Shen, G Zhu, B Li, M Xing
Journal of Nuclear Medicine 61 (2), 177-182, 2020
932020
BRAF V600E Mutation-Assisted Risk Stratification of Solitary Intrathyroidal Papillary Thyroid Cancer for Precision Treatment
Y Huang, S Qu, G Zhu, F Wang, R Liu, X Shen, D Viola, R Elisei, ...
JNCI: Journal of the National Cancer Institute 110 (4), 362-370, 2018
762018
BRAF V600E confers male sex disease-specific mortality risk in patients with papillary thyroid cancer
F Wang, S Zhao, X Shen, G Zhu, R Liu, D Viola, R Elisei, E Puxeddu, ...
Journal of clinical oncology 36 (27), 2787, 2018
632018
Association of the T1799A BRAF mutation with tumor extrathyroidal invasion, higher peripheral platelet counts, and over-expression of platelet-derived growth factor-B in …
Y Wang, M Ji, W Wang, Z Miao, P Hou, X Chen, F Xu, G Zhu, X Sun, Y Li, ...
Endocrine-related cancer 15 (1), 183-190, 2008
612008
REC8 is a novel tumor suppressor gene epigenetically robustly targeted by the PI3K pathway in thyroid cancer
D Liu, X Shen, G Zhu, M Xing
Oncotarget 6 (36), 39211, 2015
602015
BRAF V600E Status Sharply Differentiates Lymph Node Metastasis-associated Mortality Risk in Papillary Thyroid Cancer
Y Tao, F Wang, X Shen, G Zhu, R Liu, D Viola, R Elisei, E Puxeddu, ...
The Journal of Clinical Endocrinology & Metabolism 106 (11), 3228-3238, 2021
442021
Robust thyroid gene expression and radioiodine uptake induced by simultaneous suppression of BRAF V600E and histone deacetylase in thyroid cancer cells
W Cheng, R Liu, G Zhu, H Wang, M Xing
The Journal of Clinical Endocrinology & Metabolism 101 (3), 962-971, 2016
372016
TERT promoter mutation determines apoptotic and therapeutic responses of BRAF-mutant cancers to BRAF and MEK inhibitors: Achilles Heel
J Tan, R Liu, G Zhu, CB Umbricht, M Xing
Proceedings of the National Academy of Sciences 117 (27), 15846-15851, 2020
332020
Therapeutic targeting of FOS in mutant TERT cancers through removing TERT suppression of apoptosis via regulating survivin and TRAIL-R2
R Liu, J Tan, X Shen, K Jiang, C Wang, G Zhu, M Xing
Proceedings of the National Academy of Sciences 118 (11), e2022779118, 2021
162021
Epigenetically upregulated WIPF1 plays a major role in BRAF V600E-promoted papillary thyroid cancer aggressiveness
T Zhang, X Shen, R Liu, G Zhu, J Bishop, M Xing
Oncotarget 8 (1), 900, 2017
142017
BzATP activates satellite glial cells and increases the excitability of dorsal root ganglia neurons in vivo
Z Chen, C Zhang, X Song, X Cui, J Liu, NC Ford, S He, G Zhu, X Dong, ...
Cells 11 (15), 2280, 2022
82022
Stage ii differentiated thyroid cancer is a high-risk disease in patients< 45/55 years old
Z Liu, X Shen, R Liu, G Zhu, T Huang, M Xing
The Journal of Clinical Endocrinology & Metabolism 104 (11), 4941-4948, 2019
42019
Genetic trio of BRAF and TERT alterations and rs2853669TT in papillary thyroid cancer aggressiveness
R Liu, G Zhu, J Tan, X Shen, M Xing
JNCI: Journal of the National Cancer Institute, djad265, 2023
22023
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