Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models ML Schulte, A Fu, P Zhao, J Li, L Geng, ST Smith, J Kondo, RJ Coffey, ... Nature medicine 24 (2), 194-202, 2018 | 349 | 2018 |
Retaining cell–cell contact enables preparation and culture of spheroids composed of pure primary cancer cells from colorectal cancer J Kondo, H Endo, H Okuyama, O Ishikawa, H Iishi, M Tsujii, M Ohue, ... Proceedings of the National Academy of Sciences 108 (15), 6235-6240, 2011 | 314 | 2011 |
Application of cancer organoid model for drug screening and personalized therapy J Kondo, M Inoue Cells 8 (5), 470, 2019 | 185 | 2019 |
CagA mediates epigenetic regulation to attenuate let-7 expression in Helicobacter pylori-related carcinogenesis Y Hayashi, M Tsujii, J Wang, J Kondo, T Akasaka, Y Jin, W Li, ... Gut 62 (11), 1536-1546, 2013 | 136 | 2013 |
High‐throughput screening in colorectal cancer tissue‐originated spheroids J Kondo, T Ekawa, H Endo, K Yamazaki, N Tanaka, Y Kukita, H Okuyama, ... Cancer science 110 (1), 345-355, 2019 | 104 | 2019 |
Spheroid culture of primary lung cancer cells with neuregulin 1/HER3 pathway activation H Endo, J Okami, H Okuyama, T Kumagai, J Uchida, J Kondo, T Takehara, ... Journal of Thoracic Oncology 8 (2), 131-139, 2013 | 96 | 2013 |
Association of vitamin K deficiency with bone metabolism and clinical disease activity in inflammatory bowel disease S Nakajima, H Iijima, S Egawa, S Shinzaki, J Kondo, T Inoue, Y Hayashi, ... Nutrition 27 (10), 1023-1028, 2011 | 85 | 2011 |
Clinical features of post‐polypectomy bleeding associated with heparin bridge therapy T Inoue, T Nishida, A Maekawa, Y Tsujii, T Akasaka, M Kato, Y Hayashi, ... Digestive Endoscopy 26 (2), 243-249, 2014 | 59 | 2014 |
The effectiveness of an anti-human IL-6 receptor monoclonal antibody combined with chemotherapy to target colon cancer stem-like cells J Ying, M Tsujii, J Kondo, Y Hayashi, M Kato, T Akasaka, T Inoue, ... International journal of oncology 46 (4), 1551-1559, 2015 | 55 | 2015 |
p53 functional deficiency in human colon cancer cells promotes fibroblast-mediated angiogenesis and tumor growth Y Hayashi, M Tsujii, T Kodama, T Akasaka, J Kondo, H Hikita, T Inoue, ... Carcinogenesis 37 (10), 972-984, 2016 | 49 | 2016 |
Shear stress induces noncanonical autophagy in intestinal epithelial monolayers SW Kim, J Ehrman, MR Ahn, J Kondo, AAM Lopez, YS Oh, XH Kim, ... Molecular biology of the cell 28 (22), 3043-3056, 2017 | 46 | 2017 |
Discovery and structure-based optimization of potent and selective WD repeat domain 5 (WDR5) inhibitors containing a dihydroisoquinolinone bicyclic core J Tian, KB Teuscher, ER Aho, JR Alvarado, JJ Mills, KM Meyers, ... Journal of medicinal chemistry 63 (2), 656-675, 2019 | 41 | 2019 |
Dynamic change of polarity in primary cultured spheroids of human colorectal adenocarcinoma and its role in metastasis H Okuyama, J Kondo, Y Sato, H Endo, A Nakajima, JM Piulats, Y Tomita, ... The American Journal of Pathology 186 (4), 899-911, 2016 | 40 | 2016 |
Evaluation of endoscopic ultrasound image quality is necessary in endosonographic assessment of early gastric cancer invasion depth S Yamamoto, T Nishida, M Kato, T Inoue, Y Hayashi, J Kondo, T Akasaka, ... Gastroenterology Research and Practice 2012, 2012 | 39 | 2012 |
Study of glycosylation of prostate-specific antigen secreted by cancer tissue-originated spheroids reveals new candidates for prostate cancer detection H Ideo, J Kondo, T Nomura, N Nonomura, M Inoue, J Amano Scientific reports 10 (1), 2708, 2020 | 34 | 2020 |
LRIG1 regulates ontogeny of smooth muscle− derived subsets of interstitial cells of Cajal in mice J Kondo, AE Powell, Y Wang, MA Musser, EM Southard-Smith, ... Gastroenterology 149 (2), 407-419. e8, 2015 | 30 | 2015 |
Functional analysis of agalactosyl IgG in inflammatory bowel disease patients S Nakajima, H Iijima, S Shinzaki, S Egawa, T Inoue, A Mukai, Y Hayashi, ... Inflammatory bowel diseases 17 (4), 927-936, 2011 | 29 | 2011 |
Roles of double-balloon endoscopy in the diagnosis and treatment of Crohn’s disease: a multicenter experience J Kondo, H Iijima, T Abe, M Komori, S Hiyama, T Ito, A Nakama, ... Journal of gastroenterology 45, 713-720, 2010 | 27 | 2010 |
Hydrodynamic stress stimulates growth of cell clusters via the ANXA1/PI3K/AKT axis in colorectal cancer T Hagihara, J Kondo, H Endo, M Ohue, Y Sakai, M Inoue Scientific reports 9 (1), 20027, 2019 | 25 | 2019 |
Constitutive Activation of the Tumor Suppressor p53 in Hepatocytes Paradoxically Promotes Non–Cell Autonomous Liver Carcinogenesis Y Makino, H Hikita, K Fukumoto, JH Sung, Y Sakano, K Murai, S Sakane, ... Cancer Research 82 (16), 2860-2873, 2022 | 23 | 2022 |