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Max Joffe
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Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system
L Di Menna, ME Joffe, L Iacovelli, R Orlando, CW Lindsley, J Mairesse, ...
Neuropharmacology 128, 301-313, 2018
872018
Biological substrates of addiction
ME Joffe, CA Grueter, BA Grueter
Wiley Interdisciplinary Reviews: Cognitive Science 5 (2), 151-171, 2014
692014
mGlu2 and mGlu3 Negative Allosteric Modulators Divergently Enhance Thalamocortical Transmission and Exert Rapid Antidepressant-like Effects
ME Joffe, CI Santiago, KH Oliver, J Maksymetz, NA Harris, JL Engers, ...
Neuron 105 (1), 46-59. e3, 2020
652020
Mechanisms underlying prelimbic prefrontal cortex mGlu3/mGlu5-dependent plasticity and reversal learning deficits following acute stress
ME Joffe, CI Santiago, BJ Stansley, J Maksymetz, RG Gogliotti, JL Engers, ...
Neuropharmacology 144, 19-28, 2019
532019
Cocaine experience enhances thalamo-accumbens N-methyl-D-aspartate receptor function
ME Joffe, BA Grueter
Biological psychiatry 80 (9), 671-681, 2016
532016
Metabotropic glutamate receptor subtype 3 gates acute stress-induced dysregulation of amygdalo-cortical function
ME Joffe, CI Santiago, JL Engers, CW Lindsley, PJ Conn
Molecular psychiatry 24 (6), 916-927, 2019
452019
Acute restraint stress redirects prefrontal cortex circuit function through mGlu5 receptor plasticity on somatostatin-expressing interneurons
ME Joffe, J Maksymetz, JR Luschinger, S Dogra, AS Ferranti, DJ Luessen, ...
Neuron 110 (6), 1068-1083. e5, 2022
392022
Contrasting sex-dependent adaptations to synaptic physiology and membrane properties of prefrontal cortex interneuron subtypes in a mouse model of binge drinking
ME Joffe, DG Winder, PJ Conn
Neuropharmacology 178, 108126, 2020
352020
Metabotropic glutamate receptors in alcohol use disorder: physiology, plasticity, and promising pharmacotherapies
ME Joffe, SW Centanni, AA Jaramillo, DG Winder, PJ Conn
ACS chemical neuroscience 9 (9), 2188-2204, 2018
342018
Activation of the mGlu 1 metabotropic glutamate receptor has antipsychotic-like effects and is required for efficacy of M 4 muscarinic receptor allosteric modulators
SE Yohn, DJ Foster, DP Covey, MS Moehle, J Galbraith, ...
Molecular psychiatry 25 (11), 2786-2799, 2020
332020
M1 Muscarinic Receptors Modulate Fear-Related Inputs to the Prefrontal Cortex: Implications for Novel Treatments of Posttraumatic Stress Disorder
J Maksymetz, ME Joffe, SP Moran, BJ Stansley, B Li, K Temple, ...
Biological psychiatry 85 (12), 989-1000, 2019
322019
Partial mGlu 5 negative allosteric modulators attenuate cocaine-mediated behaviors and lack psychotomimetic-like effects
RW Gould, RJ Amato, M Bubser, ME Joffe, MT Nedelcovych, ...
Neuropsychopharmacology 41 (4), 1166-1178, 2016
322016
Activating mGlu3 metabotropic glutamate receptors rescues schizophrenia-like cognitive deficits through metaplastic adaptations within the hippocampus
S Dogra, BJ Stansley, Z Xiang, W Qian, RG Gogliotti, F Nicoletti, ...
Biological Psychiatry 90 (6), 385-398, 2021
312021
Role of mGlu5 Receptors and Inhibitory Neurotransmission in M1 Dependent Muscarinic LTD in the Prefrontal Cortex: Implications in Schizophrenia
A Ghoshal, SP Moran, JW Dickerson, ME Joffe, BA Grueter, Z Xiang, ...
ACS chemical neuroscience 8 (10), 2254-2265, 2017
252017
mGlu1 potentiation enhances prelimbic somatostatin interneuron activity to rescue schizophrenia-like physiological and cognitive deficits
J Maksymetz, NE Byun, DJ Luessen, B Li, RL Barry, JC Gore, ...
Cell reports 37 (5), 2021
212021
GluN1 deletions in D1-and A2A-expressing cell types reveal distinct modes of behavioral regulation
ME Joffe, SR Vitter, BA Grueter
Neuropharmacology 112, 172-180, 2017
212017
Antidepressant potential of metabotropic glutamate receptor mGlu2 and mGlu3 negative allosteric modulators
ME Joffe, PJ Conn
Neuropsychopharmacology 44 (1), 214, 2019
162019
Nuclear magnetic resonance methods for metabolic fluxomics
S Nargund, ME Joffe, D Tran, V Tugarinov, G Sriram
Systems Metabolic Engineering: Methods and Protocols, 335-351, 2013
142013
Increased Synaptic Strength and mGlu2/3 Receptor Plasticity on Mouse Prefrontal Cortex Intratelencephalic Pyramidal Cells Following Intermittent Access to Ethanol
ME Joffe, DG Winder, PJ Conn
Alcoholism: Clinical and Experimental Research 45 (3), 518-529, 2021
132021
Frontal cortex genetic ablation of metabotropic glutamate receptor subtype 3 (mGlu3) impairs postsynaptic plasticity and modulates affective behaviors
ME Joffe, CI Santiago, SAD Vermudez, NM Fisher, S Dogra, ...
Neuropsychopharmacology 46 (12), 2148-2157, 2021
102021
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