Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system L Di Menna, ME Joffe, L Iacovelli, R Orlando, CW Lindsley, J Mairesse, ... Neuropharmacology 128, 301-313, 2018 | 87 | 2018 |
Biological substrates of addiction ME Joffe, CA Grueter, BA Grueter Wiley Interdisciplinary Reviews: Cognitive Science 5 (2), 151-171, 2014 | 69 | 2014 |
mGlu2 and mGlu3 Negative Allosteric Modulators Divergently Enhance Thalamocortical Transmission and Exert Rapid Antidepressant-like Effects ME Joffe, CI Santiago, KH Oliver, J Maksymetz, NA Harris, JL Engers, ... Neuron 105 (1), 46-59. e3, 2020 | 65 | 2020 |
Mechanisms underlying prelimbic prefrontal cortex mGlu3/mGlu5-dependent plasticity and reversal learning deficits following acute stress ME Joffe, CI Santiago, BJ Stansley, J Maksymetz, RG Gogliotti, JL Engers, ... Neuropharmacology 144, 19-28, 2019 | 53 | 2019 |
Cocaine experience enhances thalamo-accumbens N-methyl-D-aspartate receptor function ME Joffe, BA Grueter Biological psychiatry 80 (9), 671-681, 2016 | 53 | 2016 |
Metabotropic glutamate receptor subtype 3 gates acute stress-induced dysregulation of amygdalo-cortical function ME Joffe, CI Santiago, JL Engers, CW Lindsley, PJ Conn Molecular psychiatry 24 (6), 916-927, 2019 | 45 | 2019 |
Acute restraint stress redirects prefrontal cortex circuit function through mGlu5 receptor plasticity on somatostatin-expressing interneurons ME Joffe, J Maksymetz, JR Luschinger, S Dogra, AS Ferranti, DJ Luessen, ... Neuron 110 (6), 1068-1083. e5, 2022 | 39 | 2022 |
Contrasting sex-dependent adaptations to synaptic physiology and membrane properties of prefrontal cortex interneuron subtypes in a mouse model of binge drinking ME Joffe, DG Winder, PJ Conn Neuropharmacology 178, 108126, 2020 | 35 | 2020 |
Metabotropic glutamate receptors in alcohol use disorder: physiology, plasticity, and promising pharmacotherapies ME Joffe, SW Centanni, AA Jaramillo, DG Winder, PJ Conn ACS chemical neuroscience 9 (9), 2188-2204, 2018 | 34 | 2018 |
Activation of the mGlu 1 metabotropic glutamate receptor has antipsychotic-like effects and is required for efficacy of M 4 muscarinic receptor allosteric modulators SE Yohn, DJ Foster, DP Covey, MS Moehle, J Galbraith, ... Molecular psychiatry 25 (11), 2786-2799, 2020 | 33 | 2020 |
M1 Muscarinic Receptors Modulate Fear-Related Inputs to the Prefrontal Cortex: Implications for Novel Treatments of Posttraumatic Stress Disorder J Maksymetz, ME Joffe, SP Moran, BJ Stansley, B Li, K Temple, ... Biological psychiatry 85 (12), 989-1000, 2019 | 32 | 2019 |
Partial mGlu 5 negative allosteric modulators attenuate cocaine-mediated behaviors and lack psychotomimetic-like effects RW Gould, RJ Amato, M Bubser, ME Joffe, MT Nedelcovych, ... Neuropsychopharmacology 41 (4), 1166-1178, 2016 | 32 | 2016 |
Activating mGlu3 metabotropic glutamate receptors rescues schizophrenia-like cognitive deficits through metaplastic adaptations within the hippocampus S Dogra, BJ Stansley, Z Xiang, W Qian, RG Gogliotti, F Nicoletti, ... Biological Psychiatry 90 (6), 385-398, 2021 | 31 | 2021 |
Role of mGlu5 Receptors and Inhibitory Neurotransmission in M1 Dependent Muscarinic LTD in the Prefrontal Cortex: Implications in Schizophrenia A Ghoshal, SP Moran, JW Dickerson, ME Joffe, BA Grueter, Z Xiang, ... ACS chemical neuroscience 8 (10), 2254-2265, 2017 | 25 | 2017 |
mGlu1 potentiation enhances prelimbic somatostatin interneuron activity to rescue schizophrenia-like physiological and cognitive deficits J Maksymetz, NE Byun, DJ Luessen, B Li, RL Barry, JC Gore, ... Cell reports 37 (5), 2021 | 21 | 2021 |
GluN1 deletions in D1-and A2A-expressing cell types reveal distinct modes of behavioral regulation ME Joffe, SR Vitter, BA Grueter Neuropharmacology 112, 172-180, 2017 | 21 | 2017 |
Antidepressant potential of metabotropic glutamate receptor mGlu2 and mGlu3 negative allosteric modulators ME Joffe, PJ Conn Neuropsychopharmacology 44 (1), 214, 2019 | 16 | 2019 |
Nuclear magnetic resonance methods for metabolic fluxomics S Nargund, ME Joffe, D Tran, V Tugarinov, G Sriram Systems Metabolic Engineering: Methods and Protocols, 335-351, 2013 | 14 | 2013 |
Increased Synaptic Strength and mGlu2/3 Receptor Plasticity on Mouse Prefrontal Cortex Intratelencephalic Pyramidal Cells Following Intermittent Access to Ethanol ME Joffe, DG Winder, PJ Conn Alcoholism: Clinical and Experimental Research 45 (3), 518-529, 2021 | 13 | 2021 |
Frontal cortex genetic ablation of metabotropic glutamate receptor subtype 3 (mGlu3) impairs postsynaptic plasticity and modulates affective behaviors ME Joffe, CI Santiago, SAD Vermudez, NM Fisher, S Dogra, ... Neuropsychopharmacology 46 (12), 2148-2157, 2021 | 10 | 2021 |