Binding of synthetic oligosaccharides to the hepatic Gal/GalNAc lectin. Dependence on fine structural features. YC Lee, RR Townsend, MR Hardy, J Lönngren, J Arnarp, M Haraldsson, ... Journal of Biological Chemistry 258 (1), 199-202, 1983 | 633 | 1983 |
CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil H Almqvist, H Axelsson, R Jafari, C Dan, A Mateus, M Haraldsson, ... Nature communications 7 (1), 11040, 2016 | 154 | 2016 |
Precipitation of galactose-specific lectins by complex-type oligosaccharides and glycopeptides: studies with lectins from Ricinus communis (agglutinin I), Erythrina indica … L Bhattacharyya, M Haraldsson, CF Brewer Biochemistry 27 (3), 1034-1041, 1988 | 93 | 1988 |
A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage MJGW Ladds, IMM Van Leeuwen, CJ Drummond, S Chu, AR Healy, ... Nature communications 9 (1), 1107, 2018 | 88 | 2018 |
Retention and apparent inversion during azide displacement of α-triflates of 15-lactones I Bruce, GWJ Fleet, A Girdhar, M Haraldsson, JM Peach, DJ Watkin Tetrahedron 46 (1), 19-32, 1990 | 65 | 1990 |
Concanavalin A interactions with asparagine-linked glycopeptides. Bivalency of bisected complex type oligosaccharides. L Bhattacharyya, M Haraldsson, CF Brewer Journal of Biological Chemistry 262 (3), 1294-1299, 1987 | 65 | 1987 |
Irreversible TrxR1 inhibitors block STAT3 activity and induce cancer cell death S Busker, W Qian, M Haraldsson, B Espinosa, L Johansson, S Attarha, ... Science advances 6 (12), eaax7945, 2020 | 58 | 2020 |
Structure-Guided Design of Novel Thiazolidine Inhibitors of O-Acetyl Serine Sulfhydrylase from Mycobacterium tuberculosis O Poyraz, VU Jeankumar, S Saxena, R Schnell, M Haraldsson, ... Journal of medicinal chemistry 56 (16), 6457-6466, 2013 | 56 | 2013 |
Synthesis from D-glucose of alexine [(1R, 2R, 3R, 7S, 8S)-3-hydroxymethyl-1, 2, 7-trihydroxypyrrolizidine], 3-epialexine and 7-epialexine GWJ Fleet, M Haraldsson, RJ Nash, LE Fellows Tetrahedron letters 29 (42), 5441-5444, 1988 | 56 | 1988 |
Membrane-depolarizing channel blockers induce selective glioma cell death by impairing nutrient transport and unfolded protein/amino acid responses M Niklasson, G Maddalo, Z Sramkova, E Mutlu, S Wee, P Sekyrova, ... Cancer research 77 (7), 1741-1752, 2017 | 34 | 2017 |
Binding and precipitating activities of Erythrina lectins with complex type carbohydrates and synthetic cluster glycosides. A comparative study of the lectins from E … L Bhattacharyya, M Haraldsson, N Sharon, H Lis, F Brewer Glycoconjugate Journal 6, 141-150, 1989 | 33 | 1989 |
Substituted azole aromatic heterocycles as inhibitors of 11β-HSD-1 MD Bartberger, CH Fotsch, M Haraldsson, DS Jean, L Johansson, ... US Patent 7,666,888, 2010 | 32 | 2010 |
Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress N Bonagas, NMS Gustafsson, M Henriksson, P Marttila, R Gustafsson, ... Nature cancer 3 (2), 156-172, 2022 | 30 | 2022 |
Tandem benzophenone amino pyridines, potent and selective inhibitors of human leukotriene C4 synthase TK Kleinschmidt, M Haraldsson, D Basavarajappa, E Lundeberg, ... Journal of Pharmacology and Experimental Therapeutics 355 (1), 108-116, 2015 | 28 | 2015 |
Synthesis of three oligosaccharides that form part of the complex type of carbohydrate moiety of glycoproteins J Arnarp, M Haraldsson, J Lönngren Carbohydrate Research 97 (2), 307-313, 1981 | 28 | 1981 |
Compounds containing an amino salicylic acid moiety linked to a sulphapyridine moiety via stable bridge H Agback, L Ahrgren, T Berglindh, M Haraldsson, G Smedegard, ... US Patent 5,302,718, 1994 | 26 | 1994 |
A drug screening assay on cancer cells chronically adapted to acidosis P Pellegrini, JT Serviss, T Lundbäck, N Bancaro, M Mazurkiewicz, ... Cancer Cell International 18, 1-15, 2018 | 25 | 2018 |
Identification of novel small molecules that inhibit STAT3-dependent transcription and function I Kolosenko, Y Yu, S Busker, M Dyczynski, J Liu, M Haraldsson, ... PLoS One 12 (6), e0178844, 2017 | 23 | 2017 |
Synthesis of three oligosaccharides that form part of the complex type of carbohydrate moeity of glycoproteins containing intersecting N-acetylglucosamine J Arnarp, M Haraldsson, J Lönngren Journal of the Chemical Society, Perkin Transactions 1, 535-539, 1985 | 23 | 1985 |
Effect on human liver glycosidases and short syntheses of 1a, 2a, 6a, 7a, 7aβ-1, 2, 6, 7-tetrahydroxypyrrolizidine from d-glycero-d-gulo-heptono-1, 4-lactone WF Collin, GWJ Fleet, M Haraldsson, IC di Bello, B Winchester Carbohydrate research 202, 105-116, 1990 | 19 | 1990 |