Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ... Science immunology 6 (62), eabl4340, 2021 | 476 | 2021 |
X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19 T Asano, B Boisson, F Onodi, D Matuozzo, M Moncada-Velez, ... Science immunology 6 (62), eabl4348, 2021 | 353 | 2021 |
Signaling through C5a receptor and C3a receptor diminishes function of murine natural regulatory T cells W Kwan, W van der Touw, E Paz-Artal, MO Li, PS Heeger Journal of Experimental Medicine 210 (2), 257-268, 2013 | 221 | 2013 |
IL-6–based mortality risk model for hospitalized patients with COVID-19 R Laguna-Goya, A Utrero-Rico, P Talayero, M Lasa-Lazaro, ... Journal of Allergy and Clinical Immunology 146 (4), 799-807. e9, 2020 | 209 | 2020 |
Magnitude and dynamics of the T-cell response to SARS-CoV-2 infection at both individual and population levels TM Snyder, RM Gittelman, M Klinger, DH May, EJ Osborne, R Taniguchi, ... MedRxiv, 2020 | 190 | 2020 |
A homozygous Fas ligand gene mutation in a patient causes a new type of autoimmune lymphoproliferative syndrome M Del-Rey, J Ruiz-Contreras, A Bosque, S Calleja, J Gomez-Rial, ... Blood 108 (4), 1306-1312, 2006 | 146 | 2006 |
T-helper cell subset response is a determining factor in COVID-19 progression FJ Gil-Etayo, P Suàrez-Fernández, O Cabrera-Marante, D Arroyo, ... Frontiers in cellular and infection microbiology 11, 624483, 2021 | 144 | 2021 |
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies J Manry, P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, ... Proceedings of the National Academy of Sciences 119 (21), 2022 | 142 | 2022 |
Cutting edge: receptors for C3a and C5a modulate stability of alloantigen-reactive induced regulatory T cells W van der Touw, P Cravedi, W Kwan, E Paz-Artal, M Merad, PS Heeger The Journal of Immunology 190 (12), 5921-5925, 2013 | 136 | 2013 |
Preformed antibodies detected by cytotoxic assay or multibead array decrease liver allograft survival: role of human leukocyte antigen compatibility M Castillo‐Rama, MJ Castro, I Bernardo, JC Meneu‐Diaz, ... Liver Transplantation 14 (4), 554-562, 2008 | 118 | 2008 |
Differential effects of the second SARS-CoV-2 mRNA vaccine dose on T cell immunity in naive and COVID-19 recovered individuals D Lozano-Ojalvo, C Camara, E Lopez-Granados, P Nozal, ... Cell reports 36 (8), 2021 | 103 | 2021 |
Longitudinal analysis of immune function in the first 3 years of life in thymectomized neonates during cardiac surgery E Mancebo, J Clemente, J Sanchez, J Ruiz-Contreras, P De Pablos, ... Clinical & Experimental Immunology 154 (3), 375-383, 2008 | 103 | 2008 |
Three new HLA-G alleles and their linkage disequilibria with HLA-A P Morales, A Corell, J Martínez-Laso, JM Martín-Villa, P Varela, ... Immunogenetics 38, 323-331, 1993 | 102 | 1993 |
Antibodies reactive to non-HLA antigens in transplant glomerulopathy R Dinavahi, A George, A Tretin, E Akalin, S Ames, JS Bromberg, ... Journal of the American Society of Nephrology 22 (6), 1168-1178, 2011 | 96 | 2011 |
Initial presenting manifestations in 16,486 patients with inborn errors of immunity include infections and noninfectious manifestations J Thalhammer, G Kindle, A Nieters, S Rusch, MRJ Seppänen, A Fischer, ... Journal of Allergy and Clinical Immunology 148 (5), 1332-1341. e5, 2021 | 95 | 2021 |
Kinetics of peripheral blood lymphocyte subpopulations predicts the occurrence of opportunistic infection after kidney transplantation M Fernández‐Ruiz, F López‐Medrano, LM Allende, A Andrés, ... Transplant International 27 (7), 674-685, 2014 | 89 | 2014 |
A point mutation in a domain of gamma interferon receptor 1 provokes severe immunodeficiency LM Allende, A López-Goyanes, E Paz-Artal, A Corell, MA Garcı́a-Pérez, ... Clinical Diagnostic Laboratory Immunology 8 (1), 133-137, 2001 | 88 | 2001 |
Monitoring of immunoglobulin levels identifies kidney transplant recipients at high risk of infection M Fernández-Ruiz, F López-Medrano, P Varela-Pena, D Lora-Pablos, ... American Journal of Transplantation 12 (10), 2763-2773, 2012 | 87 | 2012 |
Isolated IgA Anti‐β2 Glycoprotein I Antibodies in Patients with Clinical Criteria for Antiphospholipid Syndrome R Ruiz-García, M Serrano, J Ángel Martínez-Flores, S Mora, L Morillas, ... Journal of immunology research 2014 (1), 704395, 2014 | 78 | 2014 |
Antigen-presenting cell–derived complement modulates graft-versus-host disease WH Kwan, D Hashimoto, E Paz-Artal, K Ostrow, M Greter, H Raedler, ... The Journal of clinical investigation 122 (6), 2234-2238, 2012 | 73 | 2012 |