| Neutrophil-derived MMP-8 drives AMPK-dependent matrix destruction in human pulmonary tuberculosis CWM Ong, PT Elkington, S Brilha, C Ugarte-Gil, MT Tome-Esteban, ... PLoS pathogens 11 (5), e1004917, 2015 | 206 | 2015 |
| Hypoxia and tissue destruction in pulmonary TB M Belton, S Brilha, R Manavaki, F Mauri, K Nijran, YT Hong, NH Patel, ... Thorax 71 (12), 1145-1153, 2016 | 161 | 2016 |
| Doxycycline and HIV infection suppress tuberculosis-induced matrix metalloproteinases NF Walker, SO Clark, T Oni, N Andreu, L Tezera, S Singh, L Saraiva, ... American journal of respiratory and critical care medicine 185 (9), 989-997, 2012 | 161 | 2012 |
| The extracellular matrix regulates granuloma necrosis in tuberculosis B Al Shammari, T Shiomi, L Tezera, MK Bielecka, V Workman, ... The Journal of infectious diseases 212 (3), 463-473, 2015 | 123 | 2015 |
| Controlled generation of microspheres incorporating extracellular matrix fibrils for three‐dimensional cell culture VL Workman, LB Tezera, PT Elkington, SN Jayasinghe Advanced functional materials 24 (18), 2648-2657, 2014 | 108 | 2014 |
| Induced sputum MMP-1,-3 &-8 concentrations during treatment of tuberculosis CA Ugarte-Gil, P Elkington, RH Gilman, J Coronel, LB Tezera, ... PloS one 8 (4), e61333, 2013 | 106 | 2013 |
| Anti-PD-1 immunotherapy leads to tuberculosis reactivation via dysregulation of TNF-α LB Tezera, MK Bielecka, P Ogongo, NF Walker, M Ellis, ... Elife 9, e52668, 2020 | 89 | 2020 |
| Dissection of the host-pathogen interaction in human tuberculosis using a bioengineered 3-dimensional model LB Tezera, MK Bielecka, A Chancellor, MT Reichmann, BA Shammari, ... Elife 6, e21283, 2017 | 76 | 2017 |
| Tissue-resident-like CD4+ T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung P Ogongo, LB Tezera, A Ardain, S Nhamoyebonde, D Ramsuran, A Singh, ... The Journal of clinical investigation 131 (10), 2021 | 61 | 2021 |
| Matrix degradation in human immunodeficiency virus type 1–Associated tuberculosis and tuberculosis immune reconstitution inflammatory syndrome: a prospective observational study NF Walker, KA Wilkinson, G Meintjes, LB Tezera, R Goliath, JM Peyper, ... Clinical Infectious Diseases 65 (1), 121-132, 2017 | 61 | 2017 |
| Procollagen III N-terminal propeptide and desmosine are released by matrix destruction in pulmonary tuberculosis J Seddon, V Kasprowicz, NF Walker, HM Yuen, H Sunpath, L Tezera, ... The Journal of infectious diseases 208 (10), 1571-1579, 2013 | 60 | 2013 |
| A bioengineered three-dimensional cell culture platform integrated with microfluidics to address antimicrobial resistance in tuberculosis MK Bielecka, LB Tezera, R Zmijan, F Drobniewski, X Zhang, ... MBio 8 (1), 10.1128/mbio. 02073-16, 2017 | 53 | 2017 |
| Mycobacterium tuberculosis subverts negative regulatory pathways in human macrophages to drive immunopathology PT Brace, LB Tezera, MK Bielecka, T Mellows, D Garay, S Tian, L Rand, ... PLoS Pathogens 13 (6), e1006367, 2017 | 52 | 2017 |
| CD1b-restricted GEM T cell responses are modulated by Mycobacterium tuberculosis mycolic acid meromycolate chains A Chancellor, AS Tocheva, C Cave-Ayland, L Tezera, A White, ... Proceedings of the National Academy of Sciences 114 (51), E10956-E10964, 2017 | 48 | 2017 |
| Membrane type 1 matrix metalloproteinase regulates monocyte migration and collagen destruction in tuberculosis T Sathyamoorthy, LB Tezera, NF Walker, S Brilha, L Saraiva, FA Mauri, ... The Journal of Immunology 195 (3), 882-891, 2015 | 43 | 2015 |
| Gender-dependent differences in plasma matrix metalloproteinase-8 elevated in pulmonary tuberculosis T Sathyamoorthy, G Sandhu, LB Tezera, R Thomas, A Singhania, ... PloS one 10 (1), e0117605, 2015 | 42 | 2015 |
| Comprehensive plasma proteomic profiling reveals biomarkers for active tuberculosis DJ Garay-Baquero, CH White, NF Walker, M Tebruegge, HF Schiff, ... JCI insight 5 (18), 2020 | 36 | 2020 |
| Integrated transcriptomic analysis of human tuberculosis granulomas and a biomimetic model identifies therapeutic targets MT Reichmann, LB Tezera, AF Vallejo, M Vukmirovic, R Xiao, J Reynolds, ... The Journal of Clinical Investigation 131 (15), 2021 | 22 | 2021 |
| Reconsidering the Optimal Immune Response to Mycobacterium tuberculosis LB Tezera, S Mansour, P Elkington American journal of respiratory and critical care medicine 201 (4), 407-413, 2020 | 20 | 2020 |
| Quantitative and qualitative iNKT repertoire associations with disease susceptibility and outcome in macaque tuberculosis infection A Chancellor, A White, AS Tocheva, JR Fenn, M Dennis, L Tezera, ... Tuberculosis 105, 86-95, 2017 | 20 | 2017 |
Paul ElkingtonUniversity of SouthamptonVerified email at soton.ac.uk
