| Self-splicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena K Kruger, PJ Grabowski, AJ Zaug, J Sands, DE Gottschling, TR Cech cell 31 (1), 147-157, 1982 | 3293 | 1982 |
| Methods in yeast genetics A Adams, DE Gottschling, CA Kaiser, T Stearns Cold Spring Harbor Laboratory Press, 1998 | 3034* | 1998 |
| Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription DE Gottschling, OM Aparicio, BL Billington, VA Zakian Cell 63 (4), 751-762, 1990 | 1778 | 1990 |
| Dot1p modulates silencing in yeast by methylation of the nucleosome core F van Leeuwen, PR Gafken, DE Gottschling Cell 109 (6), 745-756, 2002 | 1035 | 2002 |
| The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote D Schübeler, DM MacAlpine, D Scalzo, C Wirbelauer, C Kooperberg, ... Genes & development 18 (11), 1263-1271, 2004 | 1007 | 2004 |
| TLC1: template RNA component of Saccharomyces cerevisiae telomerase MS Singer, DE Gottschling Science 266 (5184), 404-409, 1994 | 1004 | 1994 |
| Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae OM Aparicio, BL Billington, DE Gottschling Cell 66 (6), 1279-1287, 1991 | 979 | 1991 |
| Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae MS Singer, A Kahana, AJ Wolf, LL Meisinger, SE Peterson, C Goggin, ... Genetics 150 (2), 613-632, 1998 | 571 | 1998 |
| Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage. H Renauld, OM Aparicio, PD Zierath, BL Billington, SK Chhablani, ... Genes & development 7 (7a), 1133-1145, 1993 | 570 | 1993 |
| The major cytoplasmic histone acetyltransferase in yeast: links to chromatin replication and histone metabolism MR Parthun, J Widom, DE Gottschling Cell 87 (1), 85-94, 1996 | 557 | 1996 |
| An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast AL Hughes, DE Gottschling Nature 492 (7428), 261-265, 2012 | 549 | 2012 |
| Synthetic chromosome arms function in yeast and generate phenotypic diversity by design JS Dymond, SM Richardson, CE Coombes, T Babatz, H Muller, ... Nature 477 (7365), 471-476, 2011 | 520 | 2011 |
| Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases α and δ SJ Diede, DE Gottschling Cell 99 (7), 723-733, 1999 | 491 | 1999 |
| Mitochondrial dysfunction leads to nuclear genome instability via an iron-sulfur cluster defect JR Veatch, MA McMurray, ZW Nelson, DE Gottschling Cell 137 (7), 1247-1258, 2009 | 468 | 2009 |
| Identification of a small molecule inhibitor of Sir2p A Bedalov, T Gatbonton, WP Irvine, DE Gottschling, JA Simon Proceedings of the National Academy of Sciences 98 (26), 15113-15118, 2001 | 458 | 2001 |
| Telomere proteins: specific recognition and protection of the natural termini of Oxytricha macronuclear DNA DE Gottschling, VA Zakian Cell 47 (2), 195-205, 1986 | 402 | 1986 |
| Saccharomyces telomeres assume a non-nucleosomal chromatin structure. JH Wright, DE Gottschling, VA Zakian Genes & development 6 (2), 197-210, 1992 | 401 | 1992 |
| Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends AE Stellwagen, ZW Haimberger, JR Veatch, DE Gottschling Genes & development 17 (19), 2384-2395, 2003 | 386 | 2003 |
| Overcoming telomeric silencing: a trans-activator competes to establish gene expression in a cell cycle-dependent way. OM Aparicio, DE Gottschling Genes & development 8 (10), 1133-1146, 1994 | 339 | 1994 |
| Degradation-mediated protein quality control in the nucleus RG Gardner, ZW Nelson, DE Gottschling Cell 120 (6), 803-815, 2005 | 326 | 2005 |
Fred van LeeuwenNetherlands Cancer InstituteVerified email at nki.nl
