Activated human astrocyte-derived extracellular vesicles modulate neuronal uptake, differentiation and firing Y You, K Borgmann, VV Edara, S Stacy, A Ghorpade, T Ikezu Journal of extracellular vesicles 9 (1), 1706801, 2020 | 133 | 2020 |
Proteomic and biological profiling of extracellular vesicles from Alzheimer's disease human brain tissues S Muraoka, AM DeLeo, MK Sethi, K Yukawa‐Takamatsu, Z Yang, J Ko, ... Alzheimer's & Dementia 16 (6), 896-907, 2020 | 116 | 2020 |
Emerging roles of extracellular vesicles in neurodegenerative disorders Y You, T Ikezu Neurobiology of Disease 130, 104512, 2019 | 86 | 2019 |
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches JA Welsh, DCI Goberdhan, L O'Driscoll, EI Buzas, C Blenkiron, ... Journal of extracellular vesicles 13 (2), e12404, 2024 | 85 | 2024 |
Schizophrenia Related Variants in CACNA1C also Confer Risk of Autism J Li, L Zhao, Y You, T Lu, M Jia, H Yu, Y Ruan, W Yue, J Liu, L Lu, ... PloS one 10 (7), e0133247, 2015 | 81 | 2015 |
Human neural cell type‐specific extracellular vesicle proteome defines disease‐related molecules associated with activated astrocytes in Alzheimer's disease brain Y You, S Muraoka, MP Jedrychowski, J Hu, AK McQuade, ... Journal of extracellular vesicles 11 (1), e12183, 2022 | 60 | 2022 |
Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities S Ikezu, H Yeh, JC Delpech, ME Woodbury, AA Van Enoo, Z Ruan, ... Molecular psychiatry 26 (6), 1808-1831, 2021 | 57 | 2021 |
Genetic Evidence for Possible Involvement of the Calcium Channel Gene CACNA1A in Autism Pathogenesis in Chinese Han Population J Li, Y You, W Yue, M Jia, H Yu, T Lu, Z Wu, Y Ruan, L Wang, D Zhang PLoS One 10 (11), e0142887, 2015 | 32 | 2015 |
Growth arrest specific gene 7 is associated with schizophrenia and regulates neuronal migration and morphogenesis Z Zhang, F Zheng, Y You, Y Ma, T Lu, W Yue, D Zhang Molecular brain 9, 1-13, 2016 | 29 | 2016 |
The schizophrenia susceptibility gene OPCML regulates spine maturation and cognitive behaviors through Eph-Cofilin signaling Z Zhang, M Ye, Q Li, Y You, H Yu, Y Ma, L Mei, X Sun, L Wang, W Yue, ... Cell Reports 29 (1), 49-61. e7, 2019 | 22 | 2019 |
Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɛ2 for Alzheimer's disease GR Jun, Y You, C Zhu, G Meng, J Chung, R Panitch, J Hu, W Xia, ... Alzheimer's & dementia 18 (11), 2042-2054, 2022 | 20* | 2022 |
Auts2 deletion involves in DG hypoplasia and social recognition deficit: The developmental and neural circuit mechanisms J Li, X Sun, Y You, Q Li, C Wei, L Zhao, M Sun, H Meng, T Zhang, W Yue, ... Science advances 8 (9), eabk1238, 2022 | 16 | 2022 |
Chromatin remodeling gene EZH2 involved in the genetic etiology of autism in Chinese Han population J Li, Y You, W Yue, H Yu, T Lu, Z Wu, M Jia, Y Ruan, J Liu, D Zhang, ... Neuroscience Letters 610, 182-186, 2016 | 13 | 2016 |
Genetic variants in the transcription regulatory region of MEGF10 are associated with autism in Chinese Han population Z Wu, J Qin, Y You, Y Ma, M Jia, L Wang, T Lu, W Yue, Y Ruan, D Zhang, ... Scientific reports 7 (1), 2292, 2017 | 11 | 2017 |
ATP1A3 as a target for isolating neuron-specific extracellular vesicles from human brain and biofluids Y You, Z Zhang, N Sultana, M Ericsson, YA Martens, M Sun, T Kanekiyo, ... Science Advances 9 (37), eadi3647, 2023 | 8 | 2023 |
Cre-inducible adeno associated virus-mediated expression of P301L mutant Tau causes motor deficits and neuronal degeneration in the substantia nigra Y You, MB Botros, AA Van Enoo, A Bockmiller, S Herron, JC Delpech, ... Neuroscience 422, 65-74, 2019 | 8 | 2019 |
Alzheimer’s disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells Yang You,Samuel W. Hersh,Roshanak Aslebagh,Scott A. Shaffer,Seiko Ikezu ... Aging Cell, 2022 | 7 | 2022 |
Comprehensive characterization of human brain‐derived extracellular vesicles using multiple isolation methods: Implications for diagnostic and therapeutic applications Z Zhang, K Yu, Y You, P Jiang, Z Wu, MA DeTure, DW Dickson, S Ikezu, ... Journal of Extracellular Vesicles 12 (8), 12358, 2023 | 3 | 2023 |
Recommendations for reproducibility of cerebrospinal fluid extracellular vesicle studies US Sandau, SM Magaña, J Costa, JP Nolan, T Ikezu, LJ Vella, ... Journal of extracellular vesicles 13 (1), 12397, 2024 | 1 | 2024 |
369 Differentiating Dementia with Lewy Bodies and Alzheimer’s Disease Using Extracellular Vesicles M Bregendahl, A Faroqi, Z Zhang, Y You, T Ikezu, SBL De Souza, ... Journal of Clinical and Translational Science 7 (s1), 109-110, 2023 | | 2023 |