Dual inhibition of the terminal oxidases eradicates antibiotic‐tolerant Mycobacterium tuberculosis BS Lee, K Hards, CA Engelhart, EJ Hasenoehrl, NP Kalia, JS Mackenzie, ... EMBO Molecular Medicine 13 (1), e13207, 2021 | 67* | 2021 |
Inhibitors of energy metabolism interfere with antibiotic-induced death in mycobacteria BS Lee, NP Kalia, XEF Jin, EJ Hasenoehrl, M Berney, K Pethe Journal of Biological Chemistry 294 (6), 1936-1943, 2019 | 54 | 2019 |
Targeting the cytochrome oxidases for drug development in mycobacteria BS Lee, E Sviriaeva, K Pethe Progress in biophysics and molecular biology 152, 45-54, 2020 | 39 | 2020 |
Carbon metabolism modulates the efficacy of drugs targeting the cytochrome bc1:aa3 in Mycobacterium tuberculosis NP Kalia, B Shi Lee, NB Ab Rahman, GC Moraski, MJ Miller, K Pethe Scientific reports 9 (1), 8608, 2019 | 35 | 2019 |
Bedaquiline reprograms central metabolism to reveal glycolytic vulnerability in Mycobacterium tuberculosis JS Mackenzie, DA Lamprecht, R Asmal, JH Adamson, K Borah, ... Nature communications 11 (1), 6092, 2020 | 34* | 2020 |
Therapeutic potential of promiscuous targets in Mycobacterium tuberculosis BS Lee, K Pethe Current opinion in pharmacology 42, 22-26, 2018 | 26 | 2018 |
Structure guided generation of thieno [3, 2-d] pyrimidin-4-amine Mycobacterium tuberculosis bd oxidase inhibitors SM Hopfner, BS Lee, NP Kalia, MJ Miller, K Pethe, GC Moraski RSC Medicinal Chemistry 12 (1), 73-77, 2021 | 22 | 2021 |
Telacebec: an investigational antibacterial for the treatment of tuberculosis (TB) BS Lee, K Pethe Expert Opinion on Investigational Drugs 31 (2), 139-144, 2022 | 15 | 2022 |
Hydride-induced Meisenheimer complex formation reflects activity of nitro aromatic anti-tuberculosis compounds R Liu, L Markley, PA Miller, S Franzblau, G Shetye, R Ma, K Savková, ... RSC Medicinal Chemistry 12 (1), 62-72, 2021 | 4 | 2021 |
Syntheses and Structure–Activity Relationships of N-Phenethyl-Quinazolin-4-yl-Amines as Potent Inhibitors of Cytochrome bd Oxidase in Mycobacterium tuberculosis SM Hopfner, BS Lee, NP Kalia, MJ Miller, K Pethe, GC Moraski Applied Sciences 11 (19), 9092, 2021 | 3 | 2021 |
Visible light photoacoustic ophthalmoscopy and near-infrared-II optical coherence tomography in the mouse eye R Haindl, V Bellemo, P Rajendran, B Tan, M Liu, BS Lee, Q Zhou, ... APL Photonics 8 (10), 2023 | | 2023 |
Inhibiting respiration as a novel antibiotic strategy BS Lee, S Singh, K Pethe Current Opinion in Microbiology 74, 102327, 2023 | | 2023 |
Suffocating tuberculosis: oxidative phosphorylation as a target space for the development of next generation anti-tuberculosis drugs BS Lee Nanyang Technological University, 2021 | | 2021 |