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Barbara Wegiel
Barbara Wegiel
BIDMC/Harvard Medical Shool
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Year
Carbon monoxide expedites metabolic exhaustion to inhibit tumor growth
B Wegiel, D Gallo, E Csizmadia, C Harris, J Belcher, GM Vercellotti, ...
Cancer research 73 (23), 7009-7021, 2013
3422013
Heme oxygenase and carbon monoxide initiate homeostatic signaling
M Bilban, A Haschemi, B Wegiel, BY Chin, O Wagner, LE Otterbein
Journal of Molecular Medicine 86, 267-279, 2008
2752008
Hypoxia-inducible factor 1α stabilization by carbon monoxide results in cytoprotective preconditioning
BY Chin, G Jiang, B Wegiel, HJ Wang, T MacDonald, XC Zhang, D Gallo, ...
Proceedings of the National Academy of Sciences 104 (12), 5109-5114, 2007
2572007
Interleukin‐6 activates PI3K/Akt pathway and regulates cyclin A1 to promote prostate cancer cell survival
B Wegiel, A Bjartell, Z Culig, JL Persson
International journal of cancer 122 (7), 1521-1529, 2008
2262008
Carbon monoxide reverses established pulmonary hypertension
BS Zuckerbraun, BY Chin, B Wegiel, TR Billiar, E Czsimadia, J Rao, ...
The Journal of experimental medicine 203 (9), 2109-2119, 2006
2042006
Heme oxygenase-1: a metabolic nike
B Wegiel, Z Nemeth, M Correa-Costa, AC Bulmer, LE Otterbein
Antioxidants & redox signaling 20 (11), 1709-1722, 2014
1832014
Therapeutic applications of bilirubin and biliverdin in transplantation
R Öllinger, H Wang, K Yamashita, B Wegiel, M Thomas, R Margreiter, ...
Antioxidants & redox signaling 9 (12), 2175-2186, 2007
1722007
Macrophages sense and kill bacteria through carbon monoxide–dependent inflammasome activation
B Wegiel, R Larsen, D Gallo, BY Chin, C Harris, P Mannam, E Kaczmarek, ...
The Journal of clinical investigation 124 (11), 4926-4940, 2014
1702014
Go green: the anti-inflammatory effects of biliverdin reductase
B Wegiel, LE Otterbein
Frontiers in pharmacology 3, 47, 2012
1452012
Multiple cellular mechanisms related to cyclin A1 in prostate cancer invasion and metastasis
B Wegiel, A Bjartell, J Tuomela, N Dizeyi, M Tinzl, L Helczynski, E Nilsson, ...
Journal of the National Cancer Institute 100 (14), 1022-1036, 2008
1422008
Nitric oxide–dependent bone marrow progenitor mobilization by carbon monoxide enhances endothelial repair after vascular injury
B Wegiel, DJ Gallo, KG Raman, JM Karlsson, B Ozanich, BY Chin, ...
Circulation 121 (4), 537-548, 2010
1262010
Cell surface biliverdin reductase mediates biliverdin-induced anti-inflammatory effects via phosphatidylinositol 3-kinase and Akt
B Wegiel, CJ Baty, D Gallo, E Csizmadia, JR Scott, A Akhavan, BY Chin, ...
Journal of Biological Chemistry 284 (32), 21369-21378, 2009
1262009
Mechanism of purinergic activation of endothelial nitric oxide synthase in endothelial cells
CG da Silva, A Specht, B Wegiel, C Ferran, E Kaczmarek
Circulation 119 (6), 871-879, 2009
1232009
Blockade of lactate dehydrogenase-A (LDH-A) improves efficacy of anti-programmed cell death-1 (PD-1) therapy in melanoma
S Daneshmandi, B Wegiel, P Seth
Cancers 11 (4), 450, 2019
1182019
The social network of carbon monoxide in medicine
B Wegiel, DW Hanto, LE Otterbein
Trends in molecular medicine 19 (1), 3-11, 2013
1172013
Deletion of lactate dehydrogenase-A in myeloid cells triggers antitumor immunity
P Seth, E Csizmadia, A Hedblom, M Vuerich, H Xie, M Li, MS Longhi, ...
Cancer research 77 (13), 3632-3643, 2017
1152017
Heme oxygenase-1-dependent and-independent regulation of angiogenic genes expression: effect of cobalt protoporphyrin and cobalt chloride on VEGF and IL-8 synthesis in human …
A Loboda, A Jazwa, B Wegiel, A Józkowicz, J Dulak
Cellular and molecular biology (Noisy-le-Grand, France) 51 (4), 347, 2005
1132005
Biliverdin inhibits Toll-like receptor-4 (TLR4) expression through nitric oxide-dependent nuclear translocation of biliverdin reductase
B Wegiel, D Gallo, E Csizmadia, T Roger, E Kaczmarek, C Harris, ...
Proceedings of the National Academy of Sciences 108 (46), 18849-18854, 2011
1102011
Metabolic switch in the tumor microenvironment determines immune responses to anti-cancer therapy
B Wegiel, M Vuerich, S Daneshmandi, P Seth
Frontiers in oncology 8, 284, 2018
992018
Heme oxygenase-1 promotes survival of renal cancer cells through modulation of apoptosis-and autophagy-regulating molecules
P Banerjee, A Basu, B Wegiel, LE Otterbein, K Mizumura, M Gasser, ...
Journal of Biological Chemistry 287 (38), 32113-32123, 2012
952012
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