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Yanhao Lai
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Antioxidant activities of Ganoderma lucidum polysaccharides and their role on DNA damage in mice induced by cobalt-60 gamma-irradiation
W Zhao, X Jiang, W Deng, Y Lai, M Wu, Z Zhang
Food and chemical toxicology 50 (2), 303-309, 2012
782012
Crosstalk between MSH2–MSH3 and polβ promotes trinucleotide repeat expansion during base excision repair
Y Lai, H Budworth, JM Beaver, NLS Chan, Z Zhang, CT McMurray, Y Liu
Nature communications 7 (1), 12465, 2016
562016
N6-methyladenosine mediates arsenite-induced human keratinocyte transformation by suppressing p53 activation
T Zhao, D Sun, M Zhao, Y Lai, Y Liu, Z Zhang
Environmental pollution 259, 113908, 2020
532020
miR-155 mediates arsenic trioxide resistance by activating Nrf2 and suppressing apoptosis in lung cancer cells
S Gu, Y Lai, H Chen, Y Liu, Z Zhang
Scientific reports 7 (1), 12155, 2017
512017
A 5′, 8-cyclo-2′-deoxypurine lesion induces trinucleotide repeat deletion via a unique lesion bypass by DNA polymerase β
M Xu, Y Lai, Z Jiang, MA Terzidis, A Masi, C Chatgilialoglu, Y Liu
Nucleic acids research 42 (22), 13749-13763, 2014
402014
Resveratrol protects against arsenic trioxide‐induced oxidative damage through maintenance of glutathione homeostasis and inhibition of apoptotic progression
C Chen, X Jiang, Y Lai, Y Liu, Z Zhang
Environmental and molecular mutagenesis 56 (3), 333-346, 2015
362015
Base excision repair of oxidative DNA damage coupled with removal of a CAG repeat hairpin attenuates trinucleotide repeat expansion
M Xu, Y Lai, J Torner, Y Zhang, Z Zhang, Y Liu
Nucleic acids research 42 (6), 3675-3691, 2014
362014
Role of DNA polymerase beta in the genotoxicity of arsenic
Y Lai, W Zhao, C Chen, M Wu, Z Zhang
Environmental and molecular mutagenesis 52 (6), 460-468, 2011
332011
AP endonuclease 1 prevents trinucleotide repeat expansion via a novel mechanism during base excision repair
JM Beaver, Y Lai, M Xu, AH Casin, EE Laverde, Y Liu
Nucleic acids research 43 (12), 5948-5960, 2015
322015
Bypass of a 5′, 8-cyclopurine-2′-deoxynucleoside by DNA polymerase β during DNA replication and base excision repair leads to nucleotide misinsertions and DNA strand breaks
Z Jiang, M Xu, Y Lai, EE Laverde, MA Terzidis, A Masi, C Chatgilialoglu, ...
DNA repair 33, 24-34, 2015
282015
Dynamic single-cell intracellular pH sensing using a SERS-active nanopipette
J Guo, AS Rubfiaro, Y Lai, J Moscoso, F Chen, Y Liu, X Wang, J He
Analyst 145 (14), 4852-4859, 2020
262020
Instability of CTG repeats is governed by the position of a DNA base lesion through base excision repair
Y Lai, M Xu, Z Zhang, Y Liu
PloS one 8 (2), e56960, 2013
262013
Inhibition of base excision repair by natamycin suppresses prostate cancer cell proliferation
JL Vasquez, Y Lai, T Annamalai, Z Jiang, M Zhang, R Lei, Z Zhang, Y Liu, ...
Biochimie 168, 241-250, 2020
242020
Base excision repair of chemotherapeutically-induced alkylated DNA damage predominantly causes contractions of expanded GAA repeats associated with Friedreich's ataxia
Y Lai, JM Beaver, K Lorente, J Melo, S Ramjagsingh, IU Agoulnik, ...
PLoS One 9 (4), e93464, 2014
232014
Replication stress and consequential instability of the genome and epigenome
PS Tsegay, Y Lai, Y Liu
Molecules 24 (21), 3870, 2019
222019
Brevetoxin-2, is a unique inhibitor of the C-terminal redox center of mammalian thioredoxin reductase-1
W Chen, A Tuladhar, S Rolle, Y Lai, FR Del Rey, CE Zavala, Y Liu, ...
Toxicology and applied pharmacology 329, 58-66, 2017
192017
The role of NF-κB in PARP-inhibitor-mediated sensitization and detoxification of arsenic trioxide in hepatocellular carcinoma cells
Q Luo, Y Li, Y Lai, Z Zhang
The Journal of Toxicological Sciences 40 (3), 349-363, 2015
192015
Oxidative DNA damage modulates DNA methylation pattern in human breast cancer 1 (BRCA1) gene via the crosstalk between DNA polymerase β and a de novo DNA methyltransferase
Z Jiang, Y Lai, JM Beaver, PS Tsegay, ML Zhao, JK Horton, M Zamora, ...
Cells 9 (1), 225, 2020
172020
R-loops promote trinucleotide repeat deletion through DNA base excision repair enzymatic activities
EE Laverde, Y Lai, F Leng, L Balakrishnan, CH Freudenreich, Y Liu
Journal of Biological Chemistry 295 (40), 13902-13913, 2020
162020
Protection of Nrf2 against arsenite‐induced oxidative damage is regulated by the cyclic guanosine monophosphate‐protein kinase G signaling pathway
C Chen, X Jiang, S Gu, Y Lai, Y Liu, Z Zhang
Environmental toxicology 32 (8), 2004-2020, 2017
162017
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