Optimal composition and position of histidine-containing tags improves biodistribution of 99mTc-labeled DARPin G3 A Vorobyeva, A Schulga, E Konovalova, R Güler, J Löfblom, M Sandström, ... Scientific Reports 9 (1), 9405, 2019 | 62 | 2019 |
Comparative evaluation of two DARPin variants: effect of affinity, size, and label on tumor targeting properties S Deyev, A Vorobyeva, A Schulga, G Proshkina, R Guler, J Lofblom, ... Molecular pharmaceutics 16 (3), 995-1008, 2019 | 50 | 2019 |
Comparison of tumor‑targeting properties of directly and indirectly radioiodinated designed ankyrin repeat protein (DARPin) G3 variants for molecular imaging of HER2 A Vorobyeva, A Sсhulga, E Konovalova, R Güler, B Mitran, J Garousi, ... International journal of oncology 54 (4), 1209-1220, 2019 | 30 | 2019 |
Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model B Mitran, R Güler, FP Roche, E Lindström, RK Selvaraju, F Fleetwood, ... Theranostics 8 (16), 4462, 2018 | 29 | 2018 |
Novel affinity binders for neutralization of vascular endothelial growth factor (VEGF) signaling F Fleetwood, R Güler, E Gordon, S Ståhl, L Claesson-Welsh, J Löfblom Cellular and Molecular Life Sciences 73, 1671-1683, 2016 | 28 | 2016 |
Engineering Saccharomyces cerevisiae for the production and secretion of Affibody molecules V Gast, A Sandegren, F Dunås, S Ekblad, R Güler, S Thorén, ... Microbial Cell Factories 21 (1), 36, 2022 | 9 | 2022 |
Increasing thermal stability and improving biodistribution of VEGFR2-binding affibody molecules by a combination of in silico and directed evolution approaches R Güler, SF Svedmark, A Abouzayed, A Orlova, J Löfblom Scientific reports 10 (1), 18148, 2020 | 8 | 2020 |
VEGFR2-Specific Ligands Based on Affibody Molecules Demonstrate Agonistic Effects when Tetrameric in the Soluble Form or Immobilized via Spider Silk R Güler, N Thatikonda, HA Ghani, M Hedhammar, J Löfblom ACS Biomaterials Science & Engineering 5 (12), 6474-6484, 2019 | 6 | 2019 |
Biologic Evaluation of a Heterodimeric HER2-Albumin Targeted Affibody Molecule Produced by Chemo-Enzymatic Peptide Synthesis Y Liu, R Güler, Y Liao, A Vorobyeva, O Widmark, TJ Meuleman, A Koijen, ... Pharmaceutics 14 (11), 2519, 2022 | 4 | 2022 |
Generating a novel bispecific nanobody to enhance antitumor activity Q Ge, T Sun, Y Bian, X Xiao, J Zhu Pharmaceutical Fronts 2 (02), e100-e108, 2020 | 2 | 2020 |
Affibody Molecules Targeting VEGFR2-Two Turns Off and Four Turns On R Güler KTH Royal Institute of Technology, 2020 | | 2020 |
N-terminal position of histidine-glutamate-containing tag improves biodistribution of [Tc-99m] Tc-labeled DARPin G3 A Vorobyeva, A Schulga, E Konovalova, R Güler, J Löfblom, M Sandstrom, ... European Journal of Nuclear Medicine and Molecular Imaging 46 (SUPPL 1 …, 2019 | | 2019 |
Artificial VEGFR2-Specific Growth Factors Demonstrate Agonistic Effects in Both Soluble Form and When Immobilized Via Spider Silk R Güler, N Thatikonda, HA Ghani, M Hedhammar, J Löfblom | | 2018 |
In vivo imaging of vascular endothelial growth factor receptor-2 (VEGFR2) expression using biparatopic affibody construct B Mitran, R Güler, F Roche, E Lindstrom, F Fleetwood, L Claesson-Welsh, ... Journal of labelled compounds & radiopharmaceuticals 60, S178-S178, 2017 | | 2017 |
Novel high affinity affibody for radionuclide imaging of VEGFR2 in glioma vasculature: proof-of-principle in murine model B Mitran, R Guler, FP Roche, E Lindström, R Selvaraju, F Heetwood, ... European Journal of Nuclear Medicine and Molecular Imaging 44, S239-S239, 2017 | | 2017 |
Feasibility of in vivo imaging of VEGFR2 expression using high affinity antagonistic biparatopic affibody construct Z (VEGFR2)-Bp (2) B Mitran, R Güler, E Lindstrom, F Fleetwood, V Tolmachev, S Ståhl, ... European Journal of Nuclear Medicine and Molecular Imaging 43, S97-S98, 2016 | | 2016 |
Design och karaktärisering av biparatopa Affibodymolekyler mot VEGFR2 R Güler | | 2015 |
Engineering Saccharomyces Cerevisiae for the Production and Secretion of A body Molecules. V Gast, A Sandegren, F Dunås, S Ekblad, R Güler, S Thorén, ... | | |