| Structural and functional properties of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19 Y Huang, C Yang, X Xu, W Xu, S Liu Acta Pharmacologica Sinica 41 (9), 1141-1149, 2020 | 2245 | 2020 |
| Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1 W Xu, MR Edwards, DM Borek, AR Feagins, A Mittal, JB Alinger, KN Berry, ... Cell host & microbe 16 (2), 187-200, 2014 | 253 | 2014 |
| A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry Y Zhu, F Feng, G Hu, Y Wang, Y Yu, Y Zhu, W Xu, X Cai, Z Sun, W Han, ... Nature communications 12 (1), 961, 2021 | 220 | 2021 |
| The Marburg virus VP24 protein interacts with Keap1 to activate the cytoprotective antioxidant response pathway MR Edwards, B Johnson, CE Mire, W Xu, RS Shabman, LN Speller, ... Cell reports 6 (6), 1017-1025, 2014 | 109 | 2014 |
| Human IFIT3 modulates IFIT1 RNA binding specificity and protein stability B Johnson, LA VanBlargan, W Xu, JP White, C Shan, PY Shi, R Zhang, ... Immunity 48 (3), 487-499. e5, 2018 | 104 | 2018 |
| Development of RNA aptamers targeting Ebola virus VP35 JM Binning, T Wang, P Luthra, RS Shabman, DM Borek, G Liu, W Xu, ... Biochemistry 52 (47), 8406-8419, 2013 | 102 | 2013 |
| In silico derived small molecules bind the filovirus VP35 protein and inhibit its polymerase cofactor activity CS Brown, MS Lee, DW Leung, T Wang, W Xu, P Luthra, M Anantpadma, ... Journal of molecular biology 426 (10), 2045-2058, 2014 | 91 | 2014 |
| Salvianolic acid C potently inhibits SARS-CoV-2 infection by blocking the formation of six-helix bundle core of spike protein C Yang, X Pan, X Xu, C Cheng, Y Huang, L Li, S Jiang, W Xu, G Xiao, ... Signal transduction and targeted therapy 5 (1), 220, 2020 | 59 | 2020 |
| Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis W Xu, P Luthra, C Wu, J Batra, DW Leung, CF Basler, GK Amarasinghe Nature Communications 8 (1), 15576, 2017 | 53 | 2017 |
| Structural insight into the activation mechanism of human pancreatic prophospholipase A2 W Xu, L Yi, Y Feng, L Chen, J Liu Journal of biological chemistry 284 (24), 16659-16666, 2009 | 41 | 2009 |
| Repurposing clinically approved drugs for COVID-19 treatment targeting SARS-CoV-2 papain-like protease Y Xu, K Chen, J Pan, Y Lei, D Zhang, L Fang, J Tang, X Chen, Y Ma, ... International journal of biological macromolecules 188, 137-146, 2021 | 35 | 2021 |
| Drug repurposing of itraconazole and estradiol benzoate against COVID‐19 by blocking SARS‐CoV‐2 spike protein‐mediated membrane fusion C Yang, X Pan, Y Huang, C Cheng, X Xu, Y Wu, Y Xu, W Shang, X Niu, ... Advanced therapeutics 4 (5), 2000224, 2021 | 28 | 2021 |
| Structural analysis of bengamide derivatives as inhibitors of methionine aminopeptidases W Xu, JP Lu, QZ Ye Journal of medicinal chemistry 55 (18), 8021-8027, 2012 | 26 | 2012 |
| 血管活性肠肽研究进展 徐伟， 赵亚华， 孔洁 药物生物技术 9 (6), 364-368, 2002 | 26 | 2002 |
| Convalescent patient-derived monoclonal antibodies targeting different epitopes of E protein confer protection against Zika virus in a neonatal mouse model X Niu, L Zhao, L Qu, Z Yao, F Zhang, Q Yan, S Zhang, R Liang, P Chen, ... Emerging microbes & infections 8 (1), 749-759, 2019 | 25 | 2019 |
| Danshensu alleviates pseudo-typed SARS-CoV-2 induced mouse acute lung inflammation W Wang, S Li, X Xu, C Yang, X Niu, S Yin, X Pan, W Xu, G Hu, C Wang, ... Acta Pharmacologica Sinica 43 (4), 771-780, 2022 | 19 | 2022 |
| Monoclonal Antibodies against Zika Virus NS1 Protein Confer Protection via Fcγ Receptor-Dependent and -Independent Pathways L Yu, X Liu, X Ye, W Su, X Zhang, W Deng, J Luo, M Xiang, W Guo, ... MBio 12 (1), 10.1128/mbio. 03179-20, 2021 | 19 | 2021 |
| Hexon and fiber of adenovirus type 14 and 55 are major targets of neutralizing antibody but only fiber-specific antibody contributes to cross-neutralizing activity Y Feng, X Sun, X Ye, Y Feng, J Wang, X Zheng, X Liu, C Yi, M Hao, ... Virology 518, 272-283, 2018 | 19 | 2018 |
| An adenovirus serotype 2-vectored ebolavirus vaccine generates robust antibody and cell-mediated immune responses in mice and rhesus macaques Y Feng, C Li, P Hu, Q Wang, X Zheng, Y Zhao, Y Shi, S Yang, C Yi, ... Emerging microbes & infections 7 (1), 1-12, 2018 | 17 | 2018 |
| Sertraline is an effective SARS-CoV-2 entry inhibitor targeting the spike protein Y Chen, Y Wu, S Chen, Q Zhan, D Wu, C Yang, X He, M Qiu, N Zhang, ... Journal of Virology 96 (24), e01245-22, 2022 | 15 | 2022 |
Dominika BorekUniversity of Texas Southwestern Medical CenterVerified email at utsouthwestern.edu
