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Ahmed Elkamhawy
Ahmed Elkamhawy
Department of Pharmaceutical Organic chemistry, Faculty o Pharmacy, Mansoura University
Verified email at mans.edu.eg
Title
Cited by
Cited by
Year
The journey of DDR1 and DDR2 kinase inhibitors as rising stars in the fight against cancer
A Elkamhawy, Q Lu, H Nada, J Woo, G Quan, K Lee
International journal of molecular sciences 22 (12), 6535, 2021
532021
Emerging therapeutic strategies for Parkinson’s disease and future prospects: a 2021 update
NA Gouda, A Elkamhawy, J Cho
Biomedicines 10 (2), 371, 2022
412022
Targeting EGFR/HER2 tyrosine kinases with a new potent series of 6-substituted 4-anilinoquinazoline hybrids: Design, synthesis, kinase assay, cell-based assay, and molecular …
A Elkamhawy, AK Farag, ANI Viswanath, TM Bedair, DG Leem, KT Lee, ...
Bioorganic & Medicinal Chemistry Letters 25 (22), 5147-5154, 2015
402015
Identification of novel discoidin domain receptor 1 (DDR1) inhibitors using E-pharmacophore modeling, structure-based virtual screening, molecular dynamics simulation and MM …
H Nada, K Lee, L Gotina, AN Pae, A Elkamhawy
Computers in Biology and Medicine 142, 105217, 2022
382022
EGFR inhibitors from cancer to inflammation: Discovery of 4-fluoro-N-(4-(3-(trifluoromethyl) phenoxy) pyrimidin-5-yl) benzamide as a novel anti-inflammatory EGFR inhibitor
A Elkamhawy, AHE Hassan, S Paik, YS Lee, HH Lee, JS Shin, KT Lee, ...
Bioorganic Chemistry 86, 112-118, 2019
382019
Novel quinazoline-urea analogues as modulators for Aβ-induced mitochondrial dysfunction: Design, synthesis, and molecular docking study
A Elkamhawy, J Lee, BG Park, I Park, AN Pae, EJ Roh
European journal of medicinal chemistry 84, 466-475, 2014
382014
Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agents
S Kang, JM Lee, B Jeon, A Elkamhawy, S Paik, J Hong, SJ Oh, SH Paek, ...
European Journal of Medicinal Chemistry 151, 186-198, 2018
332018
Sulfonamide-based 4-anilinoquinoline derivatives as novel dual Aurora kinase (AURKA/B) inhibitors: Synthesis, biological evaluation and in silico insights
MM Al-Sanea, A Elkamhawy, S Paik, K Lee, AM El Kerdawy, BSN Abbas, ...
Bioorganic & medicinal chemistry 28 (13), 115525, 2020
312020
Novel LCK/FMS inhibitors based on phenoxypyrimidine scaffold as potential treatment for inflammatory disorders
AK Farag, A Elkamhawy, AM Londhe, KT Lee, AN Pae, EJ Roh
European Journal of Medicinal Chemistry 141, 657-675, 2017
302017
Synthesis and evaluation of 2-(3-arylureido) pyridines and 2-(3-arylureido) pyrazines as potential modulators of Aβ-induced mitochondrial dysfunction in Alzheimer's disease
A Elkamhawy, J Park, AHE Hassan, AN Pae, J Lee, BG Park, EJ Roh
European Journal of Medicinal Chemistry 144, 529-543, 2018
292018
Thiazolidine-2, 4-dione-based irreversible allosteric IKK-β kinase inhibitors: Optimization into in vivo active anti-inflammatory agents
A Elkamhawy, N youn Kim, AHE Hassan, J Park, S Paik, JE Yang, KS Oh, ...
European Journal of Medicinal Chemistry 188, 111955, 2020
282020
Discovery of a broad spectrum antiproliferative agent with selectivity for DDR1 kinase: Cell line-based assay, kinase panel, molecular docking, and toxicity studies
A Elkamhawy, J Park, NC Cho, T Sim, AN Pae, EJ Roh
Journal of Enzyme Inhibition and Medicinal Chemistry 31 (1), 158-166, 2016
272016
Synthesis and biological evaluation of novel 3-(quinolin-4-ylamino) benzenesulfonamides as carbonic anhydrase isoforms I and II inhibitors
MM Al-Sanea, A Elkamhawy, S Paik, S Bua, S Ha Lee, MA Abdelgawad, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 34 (1), 1457-1464, 2019
262019
Hit discovery of 4-amino-N-(4-(3-(trifluoromethyl) phenoxy) pyrimidin-5-yl) benzamide: A novel EGFR inhibitor from a designed small library
A Elkamhawy, S Paik, AHE Hassan, YS Lee, EJ Roh
Bioorganic Chemistry 75, 393-405, 2017
262017
Discovery of 1-(3-(benzyloxy) pyridin-2-yl)-3-(2-(piperazin-1-yl) ethyl) urea: A new modulator for amyloid beta-induced mitochondrial dysfunction
A Elkamhawy, J Park, AHE Hassan, H Ra, AN Pae, J Lee, BG Park, ...
European journal of medicinal chemistry 128, 56-69, 2017
252017
Discovery of potent and selective cytotoxic activity of new quinazoline-ureas against TMZ-resistant glioblastoma multiforme (GBM)
A Elkamhawy, ANI Viswanath, AN Pae, HY Kim, JC Heo, WK Park, ...
European journal of medicinal chemistry 103, 210-222, 2015
252015
Design, synthesis, biological evaluation and molecular modelling of 2-(2-aryloxyphenyl)-1, 4-dihydroisoquinolin-3 (2H)-ones: A novel class of TSPO ligands modulating amyloid-β …
A Elkamhawy, J Park, AHE Hassan, AN Pae, J Lee, BG Park, S Paik, J Do, ...
European journal of pharmaceutical sciences 104, 366-381, 2017
242017
Design, synthesis and biological evaluation of novel thiazolidinedione derivatives as irreversible allosteric IKK-β modulators
A Elkamhawy, N youn Kim, AHE Hassan, J Park, JE Yang, KS Oh, BH Lee, ...
European Journal of Medicinal Chemistry 157, 691-704, 2018
232018
Ligand-based design on the dog-bone-shaped BIBR1532 pharmacophoric features and synthesis of novel analogues as promising telomerase inhibitors with in vitro and in vivo …
AA Al-Karmalawy, MS Nafie, MA Shaldam, AA Elmaaty, SA Antar, ...
Journal of Medicinal Chemistry 66 (1), 777-792, 2022
212022
Melatonin analogues potently inhibit MAO-B and protect PC12 cells against oxidative Stress
A Elkamhawy, J Woo, NA Gouda, J Kim, H Nada, EJ Roh, KD Park, J Cho, ...
Antioxidants 10 (10), 1604, 2021
192021
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