Reprogramming a module of the 6-deoxyerythronolide B synthase for iterative chain elongation S Kapur, B Lowry, S Yuzawa, S Kenthirapalan, AY Chen, DE Cane, ... Proceedings of the National Academy of Sciences 109 (11), 4110-4115, 2012 | 124 | 2012 |
Comprehensive in Vitro Analysis of Acyltransferase Domain Exchanges in Modular Polyketide Synthases and Its Application for Short-Chain Ketone Production S Yuzawa, K Deng, G Wang, EEK Baidoo, TR Northen, PD Adams, L Katz, ... ACS synthetic biology 6 (1), 139-147, 2017 | 120 | 2017 |
Short-chain ketone production by engineered polyketide synthases in Streptomyces albus S Yuzawa, M Mirsiaghi, R Jocic, T Fujii, F Masson, VT Benites, ... Nature communications 9 (1), 4569, 2018 | 64 | 2018 |
Heterologous production of polyketides by modular type I polyketide synthases in Escherichia coli S Yuzawa, W Kim, L Katz, JD Keasling Current opinion in biotechnology 23 (5), 727-735, 2012 | 58 | 2012 |
Expression of histone H3 tails with combinatorial lysine modifications under the reprogrammed genetic code for the investigation on epigenetic markers TJ Kang, S Yuzawa, H Suga Chemistry & biology 15 (11), 1166-1174, 2008 | 44 | 2008 |
Broad substrate specificity of the loading didomain of the lipomycin polyketide synthase S Yuzawa, CH Eng, L Katz, JD Keasling Biochemistry 52 (22), 3791-3793, 2013 | 43 | 2013 |
Alteration of Polyketide Stereochemistry from anti to syn by a Ketoreductase Domain Exchange in a Type I Modular Polyketide Synthase Subunit CH Eng, S Yuzawa, G Wang, EEK Baidoo, L Katz, JD Keasling Biochemistry 55 (12), 1677-1680, 2016 | 38 | 2016 |
Role of a conserved arginine residue in linkers between the ketosynthase and acyltransferase domains of multimodular polyketide synthases S Yuzawa, S Kapur, DE Cane, C Khosla Biochemistry 51 (18), 3708-3710, 2012 | 33 | 2012 |
Synthetic biology of polyketide synthases S Yuzawa, TWH Backman, JD Keasling, L Katz Journal of Industrial Microbiology and Biotechnology 45 (7), 621-633, 2018 | 29 | 2018 |
In Vitro Analysis of Carboxyacyl Substrate Tolerance in the Loading and First Extension Modules of Borrelidin Polyketide Synthase A Hagen, S Poust, T de Rond, S Yuzawa, L Katz, PD Adams, CJ Petzold, ... Biochemistry 53 (38), 5975-5977, 2014 | 29 | 2014 |
Insights into polyketide biosynthesis gained from repurposing antibiotic-producing polyketide synthases to produce fuels and chemicals S Yuzawa, JD Keasling, L Katz The Journal of antibiotics 69 (7), 494-499, 2016 | 27 | 2016 |
Bio-based production of fuels and industrial chemicals by repurposing antibiotic-producing type I modular polyketide synthases: opportunities and challenges S Yuzawa, JD Keasling, L Katz The Journal of Antibiotics 70 (4), 378-385, 2017 | 26 | 2017 |
Probing the Flexibility of an Iterative Modular Polyketide Synthase with Non-Native Substrates in Vitro SC Curran, A Hagen, S Poust, LJG Chan, BM Garabedian, T de Rond, ... ACS chemical biology 13 (8), 2261-2268, 2018 | 22 | 2018 |
Construction of a Part of a 3-Hydroxypropionate Cycle for Heterologous Polyketide Biosynthesis in Escherichia coli S Yuzawa, N Chiba, L Katz, JD Keasling Biochemistry 51 (49), 9779-9781, 2012 | 21 | 2012 |
Activating an enzyme by an engineered coiled coil switch S Yuzawa, T Mizuno, T Tanaka Chemistry–A European Journal 12 (28), 7345-7352, 2006 | 20 | 2006 |
Engineered Production of Short-Chain Acyl-Coenzyme A Esters in Saccharomyces cerevisiae N Krink-Koutsoubelis, AC Loechner, A Lechner, H Link, CM Denby, ... ACS synthetic biology 7 (4), 1105-1115, 2018 | 16 | 2018 |
Reconstitution of a Highly Reducing Type II PKS System Reveals 6π-Electrocyclization Is Required for o-Dialkylbenzene Biosynthesis J Zhang, S Yuzawa, WL Thong, T Shinada, M Nishiyama, T Kuzuyama Journal of the American Chemical Society 143 (7), 2962-2969, 2021 | 15 | 2021 |
Heterologous Gene Expression of N-Terminally Truncated Variants of LipPks1 Suggests a Functionally Critical Structural Motif in the N-terminus of Modular … S Yuzawa, CB Bailey, T Fujii, R Jocic, JF Barajas, VT Benites, ... ACS chemical biology 12 (11), 2725-2729, 2017 | 12 | 2017 |
A reporter system for cytosolic protein aggregates in yeast D Romero-Suarez, T Wulff, Y Rong, T Jakociunas, S Yuzawa, JD Keasling, ... ACS Synthetic Biology 10 (3), 466-477, 2021 | 11 | 2021 |
Enzyme analysis of the polyketide synthase leads to the discovery of a novel analog of the antibiotic α-lipomycin S Yuzawa, CH Eng, L Katz, JD Keasling The Journal of Antibiotics 67 (2), 199-201, 2014 | 11 | 2014 |