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Jaime Santos
Jaime Santos
Verified email at uab.es
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Year
DisProt in 2022: improved quality and accessibility of protein intrinsic disorder annotation
F Quaglia, B Mészáros, E Salladini, A Hatos, R Pancsa, LB Chemes, ...
Nucleic acids research 50 (D1), D480-D487, 2022
1242022
AlphaFold and the amyloid landscape
F Pinheiro, J Santos, S Ventura
Journal of Molecular Biology 433 (20), 167059, 2021
542021
pH-dependent aggregation in intrinsically disordered proteins is determined by charge and lipophilicity
J Santos, V Iglesias, J Santos-Suárez, M Mangiagalli, S Brocca, I Pallarès, ...
Cells 9 (1), 145, 2020
512020
Computational prediction of protein aggregation: Advances in proteomics, conformation-specific algorithms and biotechnological applications
J Santos, J Pujols, I Pallarès, V Iglesias, S Ventura
Computational and structural biotechnology journal 18, 1403-1413, 2020
512020
α-Helical peptidic scaffolds to target α-synuclein toxic species with nanomolar affinity
J Santos, P Gracia, S Navarro, S Peña-Díaz, J Pujols, N Cremades, ...
Nature communications 12 (1), 3752, 2021
482021
Tolcapone, a potent aggregation inhibitor for the treatment of familial leptomeningeal amyloidosis
F Pinheiro, N Varejão, S Esperante, J Santos, A Velázquez‐Campoy, ...
The FEBS Journal 288 (1), 310-324, 2021
422021
ZPD-2, a small compound that inhibits α-synuclein amyloid aggregation and its seeded polymerization
S Peña-Díaz, J Pujols, M Conde-Giménez, A Čarija, E Dalfo, J García, ...
Frontiers in molecular neuroscience 12, 306, 2019
342019
Insight into the specificity and severity of pathogenic mechanisms associated with missense mutations through experimental and structural perturbation analyses
E Medina-Carmona, I Betancor-Fernández, J Santos, N Mesa-Torres, ...
Human Molecular Genetics 28 (1), 1-15, 2019
292019
DispHred: A server to predict pH-dependent order–disorder transitions in intrinsically disordered proteins
J Santos, V Iglesias, C Pintado, J Santos-Suárez, S Ventura
International journal of molecular sciences 21 (16), 5814, 2020
182020
Functional amyloids germinate in plants
J Santos, S Ventura
Trends in plant science 26 (1), 7-10, 2021
162021
Inhibition of α-synuclein aggregation and mature fibril disassembling with a minimalistic compound, ZPDm
S Peña-Díaz, J Pujols, F Pinheiro, J Santos, I Pallarés, S Navarro, ...
Frontiers in Bioengineering and Biotechnology 8, 588947, 2020
162020
SolupHred: a server to predict the pH-dependent aggregation of intrinsically disordered proteins
C Pintado, J Santos, V Iglesias, S Ventura
Bioinformatics 37 (11), 1602-1603, 2021
112021
SGnn: a web server for the prediction of prion-like domains recruitment to stress granules upon heat stress
V Iglesias, J Santos, J Santos-Suárez, C Pintado-Grima, S Ventura
Frontiers in Molecular Biosciences 8, 718301, 2021
102021
Cryptic amyloidogenic regions in intrinsically disordered proteins: function and disease association
J Santos, I Pallarès, V Iglesias, S Ventura
Computational and Structural Biotechnology Journal 19, 4192-4206, 2021
102021
Computational prediction and redesign of aberrant protein oligomerization
J Santos, V Iglesias, S Ventura
Progress in Molecular Biology and Translational Science 169, 43-83, 2020
102020
Is a cure for Parkinson’s disease hiding inside us?
J Santos, I Pallarès, S Ventura
Trends in Biochemical Sciences 47 (8), 641-644, 2022
92022
The disordered C-terminus of yeast Hsf1 contains a cryptic low-complexity amyloidogenic region
J Pujols, J Santos, I Pallarès, S Ventura
International journal of molecular sciences 19 (5), 1384, 2018
82018
The small aromatic compound SynuClean-D inhibits the aggregation and seeded polymerization of multiple α-synuclein strains
S Peña-Díaz, J Pujols, E Vasili, F Pinheiro, J Santos, ...
Journal of Biological Chemistry 298 (5), 2022
72022
A3D 2.0 update for the prediction and optimization of protein solubility
J Pujols, V Iglesias, J Santos, A Kuriata, S Kmiecik, S Ventura
Insoluble Proteins: Methods and Protocols, 65-84, 2022
72022
DisProt in 2024: improving function annotation of intrinsically disordered proteins
MC Aspromonte, MV Nugnes, F Quaglia, A Bouharoua, SCE Tosatto, ...
Nucleic Acids Research 52 (D1), D434-D441, 2024
62024
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